Ovarian injury and modern options to preserve fertility in female cancer patients treated with high dose radio-chemotherapy for hemato-oncological neoplasias and other cancers

Leukemia and Lymphoma

Volumn 33, Issue 1-2, 1999, Pages 65-76

  Meirow, Dror ^a  

^a HEBREW UNIVERSITY   (Israel)

Author keywords

Chemotherapy; Female cancer patients; Ovarian injury; Preservation of fertility

Indexed keywords

BIOPSY; CANCER CELL; CANCER CHEMOTHERAPY; CANCER PATIENT; CANCER RADIOTHERAPY; CLINICAL ARTICLE; CONTROLLED STUDY; CRYOPRESERVATION; DRUG DOSE; FEMALE; FEMALE INFERTILITY; FERTILITY; FERTILIZATION IN VITRO; HUMAN; OVARY FOLLICLE; OVARY INSUFFICIENCY; OVARY METASTASIS; PRIORITY JOURNAL; REVIEW;

EID: 0033016816     PISSN: 10428194     EISSN: None     Source Type: Journal    
DOI: 10.3109/10428199909093726     Document Type: Review

References (69)

1. Boring CC. Cancer statistics. CA Cancer J Clin. 1994; 44: 7-26.
2. Damewood MD and Growchow LB. Prospects for fertility after chemotherapy or radiation for neoplastic disease. Fertil Steril. 1986; 45: 443-446.
3. Wallace WHB, Shalet SM, Hendry JH, et al. Ovarian failure following ovarian irradiation in childhood. The radiosensitivity of human oocyte. Br J Radiol. 1989; 62:995-998.
4. Sanders JE, Hawley J, Levy W, et al. Pregnancies following high-dose cyclophosphamide with or without high-dose busulfan or total body irradiation and hone marrow transplant. Blood. 1996; 87(7): 3045-3052.
5. Li FP, Gimbrere K, Gelber RD, Sallan SE, Flamant F, Green DM, Heyn RM, Meadows AT. Outcome of pregnancy in survivors of Wilms' tumor. JAMA. 1987; 257(2): 216-9.
6. Hawkins MM, Smith RA. Pregnancy outcomes in childhood cancer survivors: probable effects of abdominal irradiation. Int. J. Cancer. 1989; 43(3): 399402.
7. Miller JJ, and Cole LJ. Changes in mouse ovaries after prolonged treatment with cyclophosphamide. Proc Soc Exp Biol Med. 1970; 133:190.
8. Warne GL, Fairley KF, Hobbs JB, Martin FI. Cyclophosphamide-induced ovarian failure. N. Engl. J. Med. 1973; 289(22): 1159-62.
9. Himelstein-Braw R, Peters H, Faber M. Morphological study of the ovaries of leukaemic children. Br. J. Cancer. 1978; 38(1): 82-7.
10. Familiari G, Caggiati A, Nottola SA, Ermini M, Di-Benedetto MR, Motta PM. Ultrastructure of human ovarian primordial follicles after combination chemotherapy for Hodgkin's disease. Hum Reprod. 1993; 8(12): 2080-2087.
11. Rose DP, Davis TE. Ovarian function in patients receiving adjuvant chemotherapy for breast cancer. Lancet. 1977; 1(8023): 1174-6.
12. Chapman RM, Sutcliffe SB, Malpas JS. Cytotoxic-induced ovarian failure in Hodgkin's disease. II. Effects on sexual function. JAMA. 1979: 242(17): 1882-4.
13. Wallace WHB, Shalet SM, Tetlow LJ, Morris Jones PH. Ovarian function following the treatment of childhood acute lymphoblastic leukemia. Med Pediat Oncol. 1993; 21: 333-339.
14. Byrne J, Fears TR, Gail MH, Pee D, Connelly RR, Austin DF, Holmes GF, Holmes FF, Latourette HB, Meigs JW. et al. Early menopause in long-term survivors of cancer during adolescence. Am. J. Obstet. Gynecol. 1992; 166(3): 788-93.
15. Generoso WM, Huff SW, Stout SK. Chemically induced dominant-lethal mutations and cell killing mouse oocytes in the advanced stages of follicular development. Mutat. Res. 1971; 11(4): 411-20.
16. Becker K, Schoneich J. Expression of genetic damage induced by alkylating agents in germ cells of female mice. Mutat. Res. 1982; 92(1-2): 447-64.
17. Katoh MA, Cain KT, Hughes LA, Foxworth LB, Bishop JB, Generoso WM. Female-specific dominant lethal effects in mice. Mutat. Res. 1990; 230(2): 205-17.
18. Albanese R. Induction and transmission of chemically induced chromosome aberrations in female germ cells. Environ. Mol. Mutagen. 1987; 10(3): 231-43.
19. Sudman PD, Rutledge JC, Bishop JB, Generoso WM. Bleomycin: female-specific dominant lethal effects in mice. Mutat. Res. 1992; 296(1, 2): 143-56.
20. Apperley JF, Reddy N. Mechanism and management of treatment related gonadal failure in recipients of high dose chemotherapy. Blood Review. 1995; 9: 93-116.
21. Jackson GH, Wood A, Taylor PR, Lennard AL, Lucraft H, Heppleston A, Robinson P, Moore J, Proctor SJ. Early high dose chemotherapy intesification with autologous bone marrow transplantation in lymphoma associated with retention of fertility and normal pregnancies in females. Leuk Lymphoma. 1997; 28(1-2): 127-32.
22. Meirow D, Lewin A, Or R, Rachmilewitz E, Slavin S, Schenker JG, Abramovich D, Ben-Yehuda D., Ovarian failure post chemotherapy in young cancer patients-risk assessment indicates the need for intervention. Fertil. Steril. 1997; Supp : S218.
23. Gosden RG, Faddy MJ. Ovarian aging, follicular depletion and steroidogenesis. Exp. Gerontol. 29: 265-74.
24. Gosden RG, Wade JC, Fraser HM, Sandow J, Faddy MJ. Impact of congenital hypogonadotropism on the radiation sensitivity of the mouse ovary. Human Reprod. 199; 12: 2483-2488.
25. Hunter MCH, Gless JP, Gazet JC. Oophoropexy and ovarian function in the treatment of Hodgkin's disease. Clin. Radiol. 1980; 31: 21-26.
26. Chapman RM, Sutcliffe SB, Malpp JS. Cytotoxic induced ovarian failure in women with Hodgkin's disease. I. Hormone function. JAMA. 1979; 242: 1877-1881.
27. Blumenfeld Z, Avivi I, Linn S, Epelbaum R, Ben Shahar M, Haim N. Prevention of irreversible chemotherapy-induced ovarian damage in young women with lymphoma by a gonadotrophin, releasing hormone agonist in parallel to chemotherapy. Hum. Reprod. 1996; 11(8): 1620-6.
28. Ataya K, Rao LV, Lawrence E. et al. Luteinizing hormone-releasing hormone agonist inhibits cyclophosphamide-induced ovarian follicular depletion in rhesus monkeys. Biol. Reprod. 1995; 52: 365-372.
29. Ataya K, Pydyn E, Ramahi-Ataya A, et al. Is radiation induced ovarian failure in rhesus monkeys preventable by Luteinizing hormone-releasing hormone aginists? Preliminary observations. J. Clin. Endocrinol. Metab. 1995; 80: 790-795.
30. Gosden RG, Wade JC, Fraser HM, Sandow J, Faddy MJ. Impact of congenital and experimental hypogonadism on the radiation sensitivity of the mouse ovary. Hum. Reprod. 1997; 12(11): 2483-2488.
31. Gosden RG, Baird DT, Wade JC, Webb R. Restoration of fertility to oophorectomized sheep by ovarian autograft stored at -196C. Hum Reprod; 1994: 9: 597-603.
32. Sanders JE, Buckner CD, Amos D, Levy W, Appelbaum FR, Doney K, Storb R, Sullivan KM, Witherspoon RP, Thomas ED. Ovarian function following marrow transplantation for aplastic anemia or leukemia. J Clin Oncol. 1988; 6: 813.
33. Chapman RM, Gonadal injury resulting from chemotherapy. Am. J. Ind. Med. 1983; 4(1-2): 149-61.
34. Meirow D, Lewin A, Ben-Yehuda D, Or R. Gynecological interventions in patients treated with high dose chemotherapy. GnRH-a prevents menorrhagia, preservation of fertility potential is indicated. Presented at the Israel Soc for Reprod Med, April 1996, Tel Aviv.
35. Friedler S, Giudice LC, Lamb EJ. Cryopreservation of embryo and ova. Fertil. Steril. 1988; 49: 743-64.
36. Parks EJ, Ruffing NA. Factors affecting low temperature survival of mammalian oocytes. Technology, 1992; 37: 59-72.
37. Pickering SJ, Braude PR, Johnson MH, et al. Transient cooling to room temperature can cause irreversible disruption of the meiotic spindle in the human oocyte. Fertil Steril. 1990; 54: 102-8.
38. Gook DA, Osborn SM, Johnson WI, Parthenogenetic activation of human oocytes following cryopreservation using 1,2-propandiol. Hum Reprod. 1995; 10: 654-8.
39. Kaufman RA, Menezo Y, Hazaot A. et al. Cocultured blastocyst cryopreservation. Fertil Steril. 1995; 64:1225-29.
40. Trounson AO, Bongso A. Fertilization and development in humans. Curr Topics Dev Biol. 1996; 32: 59-101.
41. Toth TL, Baka SG, Veeck LL. et al. Fertilization and in vitro development of cryopreserved human metaphase I oocytes. Fertil Steril. 1994; 61: 891-894.
42. Cha KY, Koo JJ, Ko JJ, et al. Pregnancy after in vitro fertilization of human follicular oocytes collected from nonstimulated cycles, their culture in vitro and their transfer in a donor oocyte program. Fertil. Steril. 1991; 55: 100-13.
43. Trounson AO, Wood C, Kausche A. In vitro maturation and the fertilization and developmental competence of oocytes recovered from untreated polycystic ovarian patients. Fertil Steril. 1994; 62: 353-362.
44. Russell JB, Knezevich KM, Fabian KF, Dickson JA. Unstimulated immature oocytes retrival: early versus midfollicular endometrial priming. Fertil Steril 1997; 67: 616-620.
45. Havotta O, Sile R, Krausz T, et al. Cryopreservation of human ovarian tissue using dimethylsulphoxide and propandiol-sucrose as cryoprotectants. Hum Rep. 1996; 11: 1268 72.
46. Newton H, Aubard Y, Rutherford A, Sharma V, Gosden RG. Low temperature storage and grafting of human ovarian tissue. Hum Reprod. 1996; 11 :1487-1491.
47. Nugent D, Meirow D, Brook PF, Aubard Y, Gosden RG. Transplantation in reproductive medicine: Previous experience, present knowledge and future prospects. Hum Reprod update 1997; 2(2): 103-117.
48. Parkes AS, and Smith AU. Regeneration of rat ovarian tissue grafted after exposure to low temperatures. Proc. Roy. Soc. Lond. B. 1953; 140: 455-470.
49. Deanesly R. Immature rat ovaries grafted after freezing and thawing. J. Endocrinol. 1954: 11 : 197-200.
50. Green SH, Smith AU, Zuckerman S. The number of oocytes in ovarian grafts after freezing and thawing. J. Endocrinol. 1956; 13: 330-334.
51. Parrott DMV. The fertility of mice with orthotopic ovarain grafts derived from frozen tissue. J. Reprod. Fertil. 1960; 1: 230-241.
52. Carroll J, And Gosden RG. Transplantation of frozen-thawed mouse primordial follicles. Hum. Reprod. 1993; 8: 1163-1167.
53. Harp R, Leibach J, Black J, Keldahl C, and Karlow A. Cryopreservation of murine ovarian tissue. Cryobiology. 1994; 31 : 336-343.
54. Felicio LS, Nelson JF, Gosden RG, et al. Restoration of ovulatory cycles by young ovarian grafts in aging mice: potentiation by long term ovariectomy decreases with age. Proc. Natl. Acad. Sci. 1983; 8O: 6076-80.
55. Lara HE, Dees WL, Hiney JK. et al. Functional recovery of the developing rat ovary after transplantation: contribution of the extrinsic innervation. Endocrinolgy. 1991; 129: 1849-1860.
56. Wade JC, and Gosden RG. Assessment of oocyte survival in ovarian cortical grafts after frozen storage and xenografting. In Schats, R. And Schoemaker, J. (Eds), Ovarian Endocrinopathies (The 8th, Reinier de Graaf Symposium). Parthenon Press. New York & London. 1994; pp. 67-70.
57. Candy CJ, Wood MJ, Whittingham DG. Follicular development in cryopreserved marmoset ovarian tissue after transplantation. Hum. Reprod. 1995; 10: 2334-2338.
58. Gougeon A. Regulation of ovarian follicular development in primates: facts and hypothesis. Endocrin Reviiews. 1996; 17: 121-155.
59. Oktay K, and Gosden RG. Human primordial follicles can grow to an early antral stage in a novel xenograft model using the hpg/Scid Mouse. In abstracts of ASRM Boston 1996: pp 6-7.
60. Oktay K, Nugent D, Newton H, Salha O, Shatterjee P. Gosden RG. Isolation and characterization of primordial follicles from fresh and cryopreserved human ovarian tissue. Fertil Steril. 1997; 67(3): 481-6.
61. Gosden RG. Restoration of fertility in sterilized mice by transferring primordial ovarian follicles. Hum. Reprod. 1990; 5: 499-504.
62. Abir R, Franks S, Mobberely MA, Moore PA, et al. Mechanical isolation and in vitro growth of preantral and small antral human follicles. Fertit. Steril. 1997; 68: 682-8.
63. Meirow D, Fasoliotis SJ, Nugent D, Gosden RG, Rutherford AJ. The technique of laparoscopic ovarian cortical biopsies in cancer patients prior to sterilising treatments. (submitted).
64. Meirow D, Ben Yehuda D, Prost D, Polliack A, Schenker JG, Rachmilewitz EA, Lewin A. Ovarian tissue banking in patients with Hodgkin's disease. Is it safe? Fertil Steril. 1997 (in press).
65. Ray GR, Trueblood HW, Enright LP, Kaplan HS, Nelsen TS. Oophropexy: A means of preserving ovarian function following pelvic megavoltage radiotherapy for Hodgkin's disease. Radiology. 1970; 96: 175-180.
66. Shaw JM, Bowles J, Koopman P, et al. Fresh and cryopreserved ovarian tissue samples from donors with lymphoma transmit the cancer to graft recipients. Hum Reprod. 1996; 11 : 1668-1673.
67. Cote RJ, Rosen PP, Hakes TB, Sedira M, Bazinet M, et al. Monoclonal antibodies detect occult breast carcinoma metastasis in the bone marrow of patients with early stage disease. Am J Surg Pathol. 1988; 12 (5):333-340.
68. Kurokawa T, Kinoshita T, Ito T, Saito H, Hotta T.Detection of minimal residual disease B cell lymphoma by PCR mediated Rnase protection assay. Leukemia. 1996; 10(7): 1222-31.
69. Moos M, Schilz R, Cremer F, Sucker C, Schmohl D, et al. Detection of minimal residual disease by polymerase chain reaction in B cell malignancies. Stem Cells. 1995; 13 Suppl 3: 42-51.