Homologous and heterologous Borrelia burgdorferi challenge of infection-derived immune rabbits using host-adapted organisms

Infection and Immunity

Volumn 69, Issue 1, 2001, Pages 593-598

  Shang, E S ^a   Wu, X Y ^a   Lovett, M A ^a   Miller, J N ^a   Blanco, D R ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIBODY SPECIFICITY; ARTICLE; BACTERIAL INFECTION; BORRELIA BURGDORFERI; CELL KILLING; CONTROLLED STUDY; ERYTHEMA CHRONICUM MIGRANS; IMMUNE RESPONSE; LYME DISEASE; NONHUMAN; PRIORITY JOURNAL; RABBIT; RECEPTOR UPREGULATION; STRAIN DIFFERENCE; VACCINATION;

ADAPTATION, PHYSIOLOGICAL; ANIMALS; ANTIGENS, SURFACE; BACTERIAL OUTER MEMBRANE PROTEINS; BACTERIAL VACCINES; BLOTTING, WESTERN; DNA GYRASE; DNA TOPOISOMERASES, TYPE II; LIPOPROTEINS; LYME DISEASE; LYME DISEASE VACCINES; POLYMERASE CHAIN REACTION; RABBITS;

EID: 0035171962     PISSN: 00199567     EISSN: None     Source Type: Journal    
DOI: 10.1128/IAI.69.1.593-598.2001     Document Type: Article

References (49)

1. A new animal model for studying Lyme disease spirochetes in a mammalian host-adapted state
2. Evidence for in vivo but not in vitro expression of a Borrelia burgdorferi outer surface protein F (OspF) homologue
3. Experimental Lyme disease in dogs produces arthritis and persistent infection
4. Specificity of infection-induced immunity among Borrelia burgdorferi sensu lato species
5. Lyme borreliosis in selected strains and ages of laboratory mice
6. Chronic Lyme borreliosis in the laboratory mouse
7. Circumvention of outer surface protein A immunity by host-adapted Borrelia burgdorferi
8. Experimental Lyme arthritis in rats infected with Borrelia burgdorferi
9. Borrelia burgdorferi strain-specific OspC-mediated immunity in mice
10. Experimental inoculation of dogs with Borrelia burgdorferi
11. DbpA, but not OspA, is expressed by Borrelia burgdorferi during spirochetemia and is a target for protective antibodies
12. A 9.0-kilobase-pair circular plasmid of Borrelia burgdorferi encodes an exported protein: Evidence for expression only during infection
13. Immune serum from rabbits infected with Borrelia burgdorferi B31 confers complete passive protection against homologous challenge
14. Selective release of the Treponema pallidum outer membrane and associated polypeptides with Triton X-114
15. OspA antibodies inhibit the acquisition of Borrelia burgdorferi by Ixodes ticks
16. The histopathology of experimentally infected hamsters with the Lyme disease spirochete, Borrelia burgdorferi
17. Borrelia burgdorferi P35 and P37 proteins, expressed in vivo, elicit protective immunity
18. Rabbit model of Lyme borreliosis: Erythema migrans, infection-derived immunity, and identification of Borrelia burgdorferi proteins associated with virulence and protective immunity
19. Acquired resistance to Borrelia burgdorferi infection in the rabbit. Comparison between outer surface protein A vaccine- and infection-derived immunity
20. Conformational nature of the Borrelia burgdorferi B31 outer surface protein C protective epitope
21. Clinical and serologic evaluations of induced Borrelia burgdorferi infection in dogs
22. Decorin-binding protein A (DbpA) of Borrelia burgdorferi is not protective when immunized mice are challenged via tick infestation and correlates with the lack of DbpA expression by B. burgdorferi in ticks
23. Active and passive immunity against Borrelia burgdorferi decorin binding protein A (DbpA) protects against infection
24. Genetic heterogenity of the genes coding for the outer surface protein C (OspC) and the flagellin of Borrelia burgdorferi
25. Infection of Syrian hamsters with Lyme disease spirochetes
26. Heterogeneity of outer membrane proteins in Borrelia burgdorferi: Comparison of osp operons of three isolates of different geographic origins
27. The relapsing fever agent Borrelia hermsii has multiple copies of its chromosome and linear plasmids
28. Seroprotective groups among isolates of Borrelia burgdorferi
29. Variability of osp genes and gene products among species of Lyme disease spirochetes
30. Genetic heterogeneity of Borrelia burgdorferi in the United States
31. Experimental chronic Lyme borreliosis in Lewis rats
32. Rapid and sensitive quantification of Borrelia burgdorferi-infected mouse tissues by continuous fluorescent monitoring of PCR
33. Early and early disseminated phases of Lyme disease in the rhesus monkey: A model for infection in humans
34. Persistence of Borrelia burgdorferi and histopathological alterations in experimentally infected animals: A comparison with histopathological findings in human Lyme disease
35. Recombination between genes encoding major outer surface proteins A and B of Borrelia burgdorferi
36. The urinary bladder, a consistent source of Borrelia burgdorferi in experimentally infected white-footed mice (Peromyscus leucopus)
37. Induction of an outer surface protein on Borrelia burgdorferi during tick feeding
38. Comparison of protection in rabbits against host-adapted and cultivated Borrelia burgdorferi following infection-derived immunity or immunization with outer membrane vesicles or outer surface protein A
39. A vaccine consisting of recombinant Borrelia burgdorferi outer-surface protein A to prevent Lyme disease: Recombinant outer-surface protein A Lyme disease vaccine study consortium
40. Virulent strain associated outer membrane proteins of Borrelia burgdorferi
41. A guinea pig model for Lyme disease
42. The spirocheteal etiology of Lyme disease
43. Vaccination against Lyme disease with recombinant Borrelia burgdorferi outer-surface lipoprotein A with adjuvant
44. Temperature-related differential expression of antigens in the Lyme disease spirochete, Borrelia burgdorferi
45. Borrelia burgdorferi genes selectively expressed in the infected host
46. Molecular cloning and immunological characterization of a novel linear-plasmid-encoded gene, pG, of Borrelia burgdorferi expressed only in vivo
47. Adult Ixodes dammini on rabbits: Development of acute inflammation in the skin and immune responses to salivary gland, midgut, and spirochetal components
48. An OspA serotyping system for Borrelia burgdorferi based on reactivity with monoclonal antibodies and OspA sequence analysis
49. Association of specific subtypes of Borrelia burgdorferi with hematogenous dissemination in early Lyme disease