Retinoblastoma family proteins induce differentiation and regulate B-myb expression in neuroblastoma cells

Medical and Pediatric Oncology

Volumn 36, Issue 1, 2001, Pages 104-107

  Eggert, Angelika ^a   Ikegaki, Naohiko ^b   Liu, Xing Ge ^a   Chou, Tom T ^b   Brodeur, Garrett M ^a  

^a CHILDREN S HOSPITAL OF PHILADELPHIA   (United States)

^b UNIVERSITY OF PENNSYLVANIA   (United States)

Author keywords

B myb; Differentiation; E2F; Neuroblastoma; p107; pRb; pRb2 p130; Retinoblastoma family

Indexed keywords

PROTEIN 107; PROTEIN P130; RETINOBLASTOMA PROTEIN; UNCLASSIFIED DRUG;

CELL DIFFERENTIATION; CELL PROLIFERATION; CONFERENCE PAPER; CONTROLLED STUDY; DEPHOSPHORYLATION; DOWN REGULATION; GENE EXPRESSION; GENETIC TRANSFECTION; HUMAN; HUMAN CELL; NEUROBLASTOMA CELL; ONCOGENE MYB; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN DETERMINATION; PROTEIN FAMILY; PROTEIN PHOSPHORYLATION; RECEPTOR UPREGULATION; RETINOBLASTOMA;

ANIMALS; CELL CYCLE PROTEINS; CELL DIFFERENTIATION; DIMETHYL SULFOXIDE; DNA-BINDING PROTEINS; E2F TRANSCRIPTION FACTORS; GENE EXPRESSION REGULATION, NEOPLASTIC; GENES, MYB; GENES, REPORTER; GENES, RETINOBLASTOMA; HUMANS; LUCIFERASES; MICE; NEOPLASM PROTEINS; NEUROBLASTOMA; NUCLEAR PROTEINS; PHOSPHOPROTEINS; PROMOTER REGIONS (GENETICS); PROTEINS; RECOMBINANT FUSION PROTEINS; RETINOBLASTOMA PROTEIN; RETINOBLASTOMA-LIKE PROTEIN P107; RETINOBLASTOMA-LIKE PROTEIN P130; TRANS-ACTIVATORS; TRANSCRIPTION FACTORS; TRANSFECTION; TRETINOIN; TUMOR CELLS, CULTURED;

EID: 0035171138     PISSN: 00981532     EISSN: None     Source Type: Journal    
DOI: 10.1002/1096-911X(20010101)36:1<104::AID-MPO1024>3.0.CO;2-9     Document Type: Conference Paper

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4. Differential protooncogene expression characterizes histopathologically indistinguishable tumors of the peripheral nervous system
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7. B-myb function can be markedly enhanced by cyclin A-dependent kinase and protein truncation
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14. The Rb2/p130 gene product is a nuclear protein whose phosphorylation is cell cycle regulated
15. Retinoblastoma-related protein pRb2/p130 and its binding to the B-myb promoter increase during human neuroblastoma differentiation
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