Mutation and analysis of Dan, the founding member of the Dan family of transforming growth factor β antagonists

Molecular and Cellular Biology

Volumn 21, Issue 2, 2001, Pages 636-643

  Dionne, M S ^a   Skarnes, W C ^a   Harland, R M ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BONE MORPHOGENETIC PROTEIN 2; BONE MORPHOGENETIC PROTEIN 4; GROWTH DIFFERENTIATION FACTOR 5; INHIBITOR PROTEIN; PROTEIN DAN; TRANSFORMING GROWTH FACTOR BETA; UNCLASSIFIED DRUG;

ANIMAL TISSUE; ARTICLE; BONE DEVELOPMENT; CONTROLLED STUDY; EMBRYO; EMBRYO DEVELOPMENT; MOUSE; NERVE FIBER GROWTH; NONHUMAN; PRIORITY JOURNAL; PROTEIN PROTEIN INTERACTION; SIGNAL TRANSDUCTION; TISSUE DISTRIBUTION;

AMINO ACID SEQUENCE; ANIMALS; AXONS; BODY PATTERNING; BONE AND BONES; BONE MORPHOGENETIC PROTEINS; CELL LINE; EMBRYO, NONMAMMALIAN; FLUORESCENT ANTIBODY TECHNIQUE; GENE EXPRESSION PROFILING; GENE TARGETING; GROWTH SUBSTANCES; IN SITU HYBRIDIZATION; MICE; MICE, KNOCKOUT; MICROINJECTIONS; MOLECULAR SEQUENCE DATA; MUTATION; PROTEINS; RNA, MESSENGER; SPINAL CORD; TRANSFORMING GROWTH FACTOR BETA; XENOPUS LAEVIS; XENOPUS PROTEINS;

EID: 0035167441     PISSN: 02707306     EISSN: None     Source Type: Journal    
DOI: 10.1128/MCB.21.2.636-643.2001     Document Type: Article

References (39)

1. Generation of cerebellar granule neurons in vivo by transplantation of BMP-treated neural progenitor cells
2. BMPs as mediators of roof plate repulsion of commissural neurons
3. Cerberus is a head-inducing secreted factor expressed in the anterior endoderm of Spemann's organizer
4. Xenopus GDF6, a new antagonist of noggin and a partner of BMPs
5. Pioneer axon guidance by UNC-129, a C. elegans TGF-beta
6. BMP signalling in early Xenopus development
7. A novel BMP expressed in developing mouse limb, spinal cord, and tail bud is a potent mesoderm inducer in Xenopus embryos
8. The decapentaplegic gene: A TGF-beta homologue controlling pattern formation in Drosophila
9. Disruption of BMP signals in embryonic Xenopus ectoderm leads to direct neural induction
10. Ventral mesodermal patterning in Xenopus embryos: Expression patterns and activities of BMP-2 and BMP-4
11. Bone morphogenetic proteins: Multifunctional regulators of vertebrate development
12. The Xenopus dorsalizing factor Gremlin identifies a novel family of secreted proteins that antagonize BMP activities
13. DVR-4 (bone morphogenetic protein-4) as a posterior-ventralizing factor in Xenopus mesoderm induction
14. Neuronal patterning by BMPs: A requirement for GDF7 in the generation of a discrete class of commissural interneurons in the mouse spinal cord
15. Homeotic transformation of the occipital bones of the skull by ectopic expression of a homeobox gene
16. XBF-2 is a transcriptional repressor that converts ectoderm into neural tissue
17. Noggin-mediated antagonism of BMP signaling is required for growth and patterning of the neural tube and somite
18. Regulation of anterior/posterior patterning of the axial skeleton by growth/differentiation factor 11
19. Expression and function of Gdf-5 during digit skeletogenesis in the embryonic chick leg bud
20. Sequence and expression of a novel mouse gene PRDC (protein related to DAN and cerberus) identified by a gene trap approach
21. Heart specific expression of mouse BMP-10 a novel member of the TGF-beta superfamily
22. Molecular cloning and characterization of a cDNA showing negative regulation in v-src-transformed 3Y1 rat fibroblasts
23. The decapentaplegic gene complex of Drosophila encodes a protein homologous to the transforming growth factor-beta gene family
24. A mouse cerberus/Dan-related gene family
25. The head inducer Cerberus is a multifunctional antagonist of Nodal, BMP and Wnt signals
26. Immunocytochemical demonstration of early appearing astroglial structures that form boundaries and pathways along axon tracts in the fetal brain
27. Capturing genes encoding membrane and secreted proteins important for mouse development
28. DAN is a secreted glycoprotein related to Xenopus cerberus
29. mRNA localization in neurons: A multipurpose mechanism?
30. Limb alterations in brachypodism mice due to mutations in a new member of the TGF beta-superfamily
31. Identification of drm, a novel gene whose expression is suppressed in transformed cells and which can inhibit growth of normal but not transformed cells in culture
32. Purification and characterization of novel bone-inducing factors
33. Whole mount in situ hybridization of vertebrate embryos
34. Mesodermal patterning by an inducer gradient depends on secodary cell-cell communication
35. Novel regulators of bone formation: Molecular clones and activities