SCCA2 inhibits TNF-mediated apoptosis in transfected HeLa cells. The reactive centre loop sequence is essential for this function and TNF-induced cathepsin G is a candidate target

European Journal of Biochemistry

Volumn 268, Issue 22, 2001, Pages 5868-5875

  McGettrick, Anne F ^a   Barnes, Ruth C ^a   Worrall, D Margaret ^a  

^a UNIVERSITY COLLEGE DUBLIN   (Ireland)

Author keywords

Apoptosis; Caspase 3; Cathepsin G; Leupin; SCCA2; TNF

Indexed keywords

AMINO ACID; CASPASE 3; CATHEPSIN G; COMPLEMENTARY DNA; DNA FRAGMENT; SQUAMOUS CELL CARCINOMA ANTIGEN; SQUAMOUS CELL CARCINOMA ANTIGEN 2; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG;

APOPTOSIS; ARTICLE; CELL SURVIVAL; CONTROLLED STUDY; DNA CLEAVAGE; DNA FLANKING REGION; ENZYME ACTIVATION; GENE MUTATION; GENETIC TRANSFECTION; HELA CELL; HUMAN; HUMAN CELL; INHIBITION KINETICS; MATHEMATICAL MODEL; PRIORITY JOURNAL; PROTECTION; PROTEIN EXPRESSION; PROTEIN TARGETING; REDUCTION;

ANTIGENS, NEOPLASM; APOPTOSIS; CASPASE 3; CASPASES; CATHEPSINS; ENZYME INDUCTION; ESCHERICHIA COLI; HELA CELLS; HUMANS; MUTAGENESIS, SITE-DIRECTED; RECOMBINANT PROTEINS; SERINE ENDOPEPTIDASES; SERPINS; TRANSFECTION; TUMOR NECROSIS FACTOR-ALPHA;

EID: 0035162837     PISSN: 00142956     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.0014-2956.2001.02535.x     Document Type: Article

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