Mechanisms of altered transcription by cigarette smoke

Toxicological Sciences

Volumn 59, Issue 1, 2001, Pages 1-2

  Freed, B M ^a   Ouyang, Y ^a   McCue, J M ^a  

^a UNIVERSITY OF COLORADO   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ACETALDEHYDE; ACROLEIN; ANTIOXIDANT; CATECHOL; CIGARETTE SMOKE; CYTOKINE; DNA; FREE RADICAL; GLUTAMATE CYSTEINE LIGASE; GLUTATHIONE; HYDROQUINONE; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; IMMUNOGLOBULIN KAPPA CHAIN; OXYGEN RADICAL; PEROXYNITRITE; RIBONUCLEOTIDE REDUCTASE; THIOREDOXIN;

ARTICLE; CELL PROTECTION; CHEMICAL COMPOSITION; CIGARETTE SMOKING; CONTROLLED STUDY; CYTOKINE PRODUCTION; DNA STRAND BREAKAGE; DNA SYNTHESIS INHIBITION; DNA TRANSCRIPTION; ENVIRONMENTAL EXPOSURE; ENZYME ACTIVITY; HUMAN; HUMAN CELL; IMMUNE RESPONSE; LUNG DISEASE; OXIDATION REDUCTION REACTION; OXIDATIVE STRESS; PROTEIN DEGRADATION; PROTEIN DNA BINDING; PROTEIN PHOSPHORYLATION; SIGNAL TRANSDUCTION; TRANSCRIPTION REGULATION;

HUMANS; LUNG; OXIDATIVE STRESS; SMOKING; TRANSCRIPTION, GENETIC;

EID: 0035156067     PISSN: 10966080     EISSN: None     Source Type: Journal    
DOI: 10.1093/toxsci/59.1.1     Document Type: Article

References (12)

1. Environmental tobacco smoke is just as damaging to DNA as mainstream smoke
2. Pathobiological effects of acetaldehyde in cultured human epithelial cells and fibroblasts
3. Cytokines, growth factors and oxidative stress in HepG2 cells treated with ethanol, acetaldehyde, and LPS
4. Recent advances towards understanding redox mechanisms in the activation of nuclear factor κB
5. The molecular effects of acrolein
6. Acrolein-induced cell death in human alveolar macrophages
7. Thioredoxin regulates DNA binding activity of NF-κB by reduction of a disulphide bond involving cysteine 62
8. Exposure to cigarette tar inhibits ribonucleotide reductase and blocks lymphocyte proliferation
9. Evidence for peroxynitrites as an oxidative stress-inducing compound of aqueous cigarette smoke fractions
10. Suppression of human IL-1β, IL-2, IFNγ and TNFα production by cigarette smoke extracts
11. Fractionation of aqueous cigarette tar extracts: Fractions that contain the tar radical cause DNA damage
12. Regulation of redox glutathione levels and gene transcription in lung inflammation: Therapeutic approaches