CENP-F gene amplification and overexpression in head and neck squamous cell carcinomas

Head and Neck

Volumn 23, Issue 2, 2001, Pages 104-112

  De La Guardia, Carola ^a   Casiano, Carlos A ^b   Trinidad Pinedo, Juan ^a   Báez, Adriana ^c  

^a UNIVERSITY OF PUERTO RICO   (Puerto Rico)

^b LOMA LINDA UNIVERSITY SCHOOL OF MEDICINE   (United States)

^c UNIVERSITY OF PUERTO RICO SCHOOL OF MEDICINE   (Puerto Rico)

Author keywords

c MYC; CENP F; Gene amplification; Head and neck cancer

Indexed keywords

MESSENGER RNA;

ADULT; AGED; ARTICLE; CANCER GENETICS; FEMALE; GENE AMPLIFICATION; GENE OVEREXPRESSION; HEAD AND NECK CARCINOMA; HUMAN; MAJOR CLINICAL STUDY; MALE; ONCOGENE C MYC; PRIORITY JOURNAL; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SQUAMOUS CELL CARCINOMA;

ADULT; AGED; CARCINOMA, SQUAMOUS CELL; CENTROMERE; CHROMOSOMAL PROTEINS, NON-HISTONE; FEMALE; GENE AMPLIFICATION; GENE EXPRESSION REGULATION, NEOPLASTIC; GENES, MYC; HEAD AND NECK NEOPLASMS; HUMANS; MALE; MICROFILAMENT PROTEINS; MIDDLE AGED; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, MESSENGER;

EID: 0035148254     PISSN: 10433074     EISSN: None     Source Type: Journal    
DOI: 10.1002/1097-0347(200102)23:2<104::AID-HED1005>3.0.CO;2-0     Document Type: Article

References (51)

1. Chemotherapy and chemoprevention
2. Head and neck cancer
3. Oncogenic proteins as tumor antigens
4. Role of amplified genes in the production of autoantibodies
5. A novel cytoplasmic protein with RNA-binding motifs is an autoantigen in human hepatocellular carcinoma
6. High frequency of neoplasia in patients with autoantibodies to centromere protein CENP-F
7. Mitosin (a new proliferation marker) correlates with clinical outcome in node-negative breast cancer
8. Immunohistochemical analysis of the proliferation associated nuclear antigen CENP-F in non-Hodgkin's lymphoma
9. Circulating p53 antibodies as early markers of oral cancer: Correlation with p53 alterations
10. Monitoring of p53 autoantibodies in lung cancer during therapy: Relationship to response to treatment
11. A new prognostic indicator for head and neck cancer - p53 serum antibodies?
12. Circulating antibodies against c-myc oncogene product in sera of colorectal cancer patients
13. Myc overexpression and detection of auto-antibodies against L-Myc in both the serum and pleural effusion from a patient with non-small cell lung cancer
14. c-myc Oncogene copy number in squamous cell carcinoma of the head and neck
15. MYC amplification in squamous cell carcinomas of the head and neck
16. Oncogene amplification in squamous cell carcinoma of the head and neck
17. Analysis of gene amplification in head and neck squamous cell carcinoma
18. A multiple genetic lesions in laryngeal squamous cell carcinomas
19. Autoantibodies to a novel cell cycle-regulated protein that accumulates in the nuclear matrix during S phase and is localized in the kinetochore and spindle midzone during mitosis
20. The C-terminus of mitosin is essential for its nuclear localization, centromere/kinetochore targeting and dimerization
21. Characterization of a novel 350kD nuclear phosphoprotein that is specifically involved in mitotic-phase progression
22. d/CENP-F in disorders associated with cell proliferation
23. d/CENP-F and PCNA, in differentiation and drug-induced growth inhibition using two-parameter flow cytometry
24. Nuclear autoantigen p330/CENP-F: A marker for cell proliferation in human malignancies
25. Markers of cell proliferation in normal epithelia and dysplastic leukoplakias of the oral cavity
26. Chromosomal localization of the genes encoding the kinetochore proteins CENPE and CENPF to human chromosomes 4q24→q25 and 1q32→q41, respectively, by fluorescence in situ hybridization
27. Comparative genomic hybridization detects novel deletions and amplifications in head and neck squamous cell carcinomas
28. Assessment of chromosomal gains and losses in oral squamous cell carcinoma by comparative genomic hybridisation
29. Genomic alterations associated with malignancy in head and neck cancer
30. Molecular characterization of a novel amplicon at 1q21-q22 frequently observed in human sarcomas
31. Identification of a novel amplicon at 1q31 in pancreatic cancer cell lines
32. Myc function and regulation
33. Amplification of c-myc in hepatocellular carcinoma: Correlation with clinicopathologic features, proliferative activity and p53 overexpression
34. Quantitation of MYC gene expression in sporadic breast tumors with a real-time reverse transcription-PCR assay
35. Over-expression and amplification of the c-myc gene in human urothelial carcinoma
36. Proliferation of epithelia of noninvolved mucosa in patients with head and neck cancer
37. High incidence of p53 mutations in primary and metastatic head and neck tumors. Frequent protein overexpression in normal epithelium
38. c-myc Oncogene alterations in human thyroid carcinomas
39. Separation of leukocytes from blood and bone marrow
40. Cyclin D1 abnormalities and tobacco exposure in head and neck squamous cell carcinoma
41. Low-level c-myc amplification in human colonic carcinoma cell lines and tumors: A frequent p53-independent mutation associated with improved outcome in a randomized multi-institutional trial
42. Moderate amplifications of the c-myc gene correlate with molecular and clinicopathological parameters in colorectal cancer
43. Loss of amplified c-myc genes in the spontaneously differentiated HL-60 cells
44. c-myc Copy number gains in bladder cancer detected by fluorescence in situ hybridization
45. Low level c-myc gene amplification in gastric cancer detected by dual color fluorescence in situ hybridization analysis
46. Heterogeneity of MYCN amplification in a child with stroma-rich neuroblastoma (ganglioneuroblastoma)
47. Amplification of c-myc, K-sam, and c-met in gastric cancers: Detection by fluorescence in situ hybridization
48. Amplification of cellular oncogenes: A predictor of clinical outcome in human cancer
49. Overexpression and amplification of c-myc during progression of human colorectal cancer
50. Characterization of the kinetochore binding domain of CENP-E reveals interactions with the kinetochore proteins CENP-F and hBUBR1