Splicing factor Slt11p and its involvement in formation of U2/U6 helix II in activation of the yeast spliceosome

Molecular and Cellular Biology

Volumn 21, Issue 4, 2001, Pages 1011-1023

  Xu, D ^a   Friesen, J D ^a  

^a UNIVERSITY OF TORONTO   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

RNA; RNA BINDING PROTEIN; SMALL NUCLEAR RNA;

ARTICLE; CELL CYCLE; GENE MUTATION; NONHUMAN; PRIORITY JOURNAL; RNA BINDING; RNA SPLICING; RNA STRUCTURE; SPLICEOSOME; YEAST;

AMINO ACID SEQUENCE; BASE SEQUENCE; FUNGAL PROTEINS; MOLECULAR SEQUENCE DATA; MUTAGENESIS, SITE-DIRECTED; NUCLEIC ACID CONFORMATION; RIBONUCLEOPROTEINS, SMALL NUCLEAR; RNA SPLICING; RNA, FUNGAL; RNA, SMALL NUCLEAR; RNA-BINDING PROTEINS; SACCHAROMYCES CEREVISIAE; SACCHAROMYCES CEREVISIAE PROTEINS; SEQUENCE HOMOLOGY, AMINO ACID; SPLICEOSOMES;

EID: 0035144581     PISSN: 02707306     EISSN: None     Source Type: Journal    
DOI: 10.1128/MCB.21.4.1011-1023.2001     Document Type: Article

References (38)

1. Cross-intron bridging interactions in the yeast commitment complex are conserved in mammals
2. The yeast MUD2 protein: An interaction with PRP11 defines a bridge between commitment complexes and U2 snRNP addition
3. An element in human U6 RNA destabilizes the U4/U6 spliceosomal RNA complex
4. Requirement of SLU7 in yeast pre-mRNA splicing is dictated by the distance between the branchpoint and the 3′ splice site
5. Conserved structures and diversity of functions of RNA-binding proteins
6. A mechanism to enhance mRNA splicing fidelity: The RNA-dependent ATPase Prp16 governs usage of a discard pathway for aberrant lariat intermediates
7. Spliceosome assembly in yeast
8. Allele-specific genetic interactions between Prp8 and RNA active site residues suggest a function for Prp8 at the catalytic core of the spliceosome
9. Functionally redundant interactions between U2 and U6 spliceosomal snRNAs
10. Specificity of Prp24 binding to RNA: A role for Prp24 in the dynamic interaction of U4 and U6 snRNAs
11. Evidence for a Prp24 binding site in U6 snRNA and in a putative intermediate in the annealing of U6 and U4 snRNAs
12. The structure and function of proteins involved in mammalian pre-mRNA splicing
13. Splicing factor Prp8 governs U4/U6 unwinding during activation of the spliceosome
14. A spontaneous duplication in U6 spliceosomal RNA uncouples the early and late functions of the ACAGA element in vivo
15. Large scale identification of genes involved in cell surface biosynthesis and architecture in Saccharomyces cerevisiae
16. The role of branchpoint-3′ splicing site spacing and interaction between intron terminal nucleotides in 3′ splice site selection in Saccharomyces cerevisiae
17. Dynamic RNA-RNA interactions in the spliceosome
18. Randomization-selection analysis of snRNAs in vivo: Evidence for a tertiary interaction in the spliceosome
19. Myb-related fission yeast cdc5p is a component of a 40S snRNP-containing complex and is essential for pre-mRNA splicing
20. Identification of novel genes required for yeast pre-mRNA splicing by means of cold-sensitive mutations
21. The Saccharomyces cerevisiae Prp5 protein has RNA-dependent ATPase activity with specificity for U2 small nuclear RNA
22. The invariant U5 snRNA loop 1 sequence is dispensable for the first catalytic step of pre-mRNA splicing in yeast
23. YRA1, an essential Saccharomyces cerevisiae gene, encodes a novel nuclear protein with RNA annealing activity
24. Three recognition events at the branch site adenine
25. RNA unwinding in U4/U6 snRNPs requires ATP hydrolysis and the DEIH-box splicing factor Brr2
26. A spliceosomal recycling factor that reanneals U4 and U6 small nuclear ribonucleoprotein particles
27. Prp22, a DExH-box RNA helicase, plays two distinct roles in yeast pre-mRNA splicing
28. Identification of functional U1 snRNA-pre-mRNA complexes committed to spliceosome assembly and splicing
29. Mechanical devices of the spliceosome: Motors, clocks, springs, and things
30. An RNA switch at the 5′ splice site requires ATP and the DEAD box protein Prp28p
31. Yeast precursor mRNA processing protein PRP19 associates with the spliceosome concomitant with or just after dissociation of U4 small nuclear RNA
32. The splicing factor PRP2, a putative RNA helicase, interacts directly with pre-mRNA
33. The second catalytic step of pre-mRNA splicing
34. Interactions of small nuclear RNA's with precursor messenger RNA during in vitro splicing
35. A base-pairing interaction between U2 and U6 small nuclear RNAs occurs in >150S complexes in HeLa cell extract: Implications for the spliceosome assembly pathway
36. An RNA-dependent ATPase associated with U2/U6 snRNAs in pre-mRNA splicing
37. Synthetic lethality of yeast slt mutations with U2 small nuclear RNA mutations suggests functional interactions between U2 and U5 snRNPs that are important for both steps of pre-mRNA splicing