Analysis for loss of heterozygosity (LOH) of p53 allele in tumors derived from p53+/- and CD-1 mice following repeated subcutaneous injections of solutions containing antioxidants

Environmental and Molecular Mutagenesis

Volumn 37, Issue 1, 2001, Pages 27-30

  Youssef, Ashraf F ^a   Borellini, Flavia ^b   Jacobson Kram, David ^b   Fort, Farrel L ^a  

^a TAP Pharmaceuticals   (United States)

^b BioReliance   (United States)

Author keywords

CD 1 mice; LOH; p53 deficient mice; PCR

Indexed keywords

ANTIOXIDANT; ASCORBIC ACID; BISULFITE; DNA; PROTEIN P53;

ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CARCINOGENICITY; CONTROLLED STUDY; DNA SEQUENCE; FIBROSARCOMA; GENE MUTATION; GENOME; HETEROZYGOSITY LOSS; MOUSE; NONHUMAN; POLYMERASE CHAIN REACTION; TUMOR SUPPRESSOR GENE;

ALLELES; ANIMALS; ANTIOXIDANTS; ASCORBIC ACID; CARCINOGENICITY TESTS; FEMALE; FIBROSARCOMA; HETEROZYGOTE; INJECTIONS, SUBCUTANEOUS; LOSS OF HETEROZYGOSITY; MALE; MICE; MICE, INBRED C57BL; POLYMERASE CHAIN REACTION; RHABDOMYOSARCOMA; SENSITIVITY AND SPECIFICITY; SOFT TISSUE NEOPLASMS; SULFITES; TUMOR SUPPRESSOR PROTEIN P53;

EID: 0035144351     PISSN: 08936692     EISSN: None     Source Type: Journal    
DOI: 10.1002/1098-2280(2001)37:1<27::AID-EM1003>3.0.CO;2-B     Document Type: Article

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