Preliminary studies on the effect of dehydroepiandrosterone (DHEA) on both constitutive and phytohaemagglutinin (PHA)-inducible IL-6 and IL-2 mRNA expression and cytokine production in human spleen mononuclear cell suspensions in vitro

Clinical and Experimental Immunology

Volumn 123, Issue 1, 2001, Pages 28-35

  Young, D G ^a   Skibinski, G ^a   Skibinska, A ^a   Mason, J I ^b   James, Keith ^a,b  

^a Department of Clinical and Surgical Sciences ^*  (United Kingdom)

^b UNIVERSITY OF EDINBURGH   (United Kingdom)

Author keywords

Cytokines; Dehydroepiandrosterone; Human; In vitro; mRNA; Spleen

Indexed keywords

CYCLOSPORIN; DEXAMETHASONE; GAMMA INTERFERON; INTERLEUKIN 2; INTERLEUKIN 6; MESSENGER RNA; PHYTOHEMAGGLUTININ; PRASTERONE; TUMOR NECROSIS FACTOR ALPHA;

ADOLESCENT; ADULT; AGED; ARTICLE; CYTOKINE PRODUCTION; CYTOKINE RELEASE; DRUG EFFECT; DRUG MEGADOSE; FEMALE; GENE EXPRESSION; HUMAN; HUMAN CELL; HUMAN TISSUE; IMMUNOMODULATION; LYMPHOID TISSUE; MALE; MONONUCLEAR CELL; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL;

ADJUVANTS, IMMUNOLOGIC; ADOLESCENT; ADULT; AGED; CELLS, CULTURED; CYCLOSPORINS; CYTOKINES; DEHYDROEPIANDROSTERONE; DEXAMETHASONE; DOSE-RESPONSE RELATIONSHIP, IMMUNOLOGIC; FEMALE; HUMANS; IMMUNOSUPPRESSIVE AGENTS; INTERLEUKIN-2; INTERLEUKIN-6; LEUKOCYTES, MONONUCLEAR; MALE; MIDDLE AGED; PHYTOHEMAGGLUTININS; RNA, MESSENGER; SPLEEN;

EID: 0035140514     PISSN: 00099104     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1365-2249.2001.01445.x     Document Type: Article

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