Application of DNA microarrays to study human alcoholism

Journal of Biomedical Science

Volumn 8, Issue 1, 2001, Pages 28-36

  Lewohl, Jo M ^b   Dodd, Peter R ^b   Mayfield, R Dayne ^a   Harris, R Adron ^a  

^a UNIVERSITY OF TEXAS AT AUSTIN   (United States)

^b UNIVERSITY OF QUEENSLAND   (Australia)

Author keywords

Frontal cortex; Gene chip; Gene expression; Myelin

Indexed keywords

ALCOHOL; MYELIN;

ALCOHOL TOLERANCE; ALCOHOLISM; DISEASE SEVERITY; DNA HYBRIDIZATION; DNA MICROARRAY; FRONTAL CORTEX; GENDER; GENE EXPRESSION; HUMAN; NEUROTOXICITY; PRIORITY JOURNAL; REVIEW;

ALCOHOL-RELATED DISORDERS; ALCOHOLISM; GENE EXPRESSION PROFILING; HUMANS; OLIGONUCLEOTIDE ARRAY SEQUENCE ANALYSIS;

EID: 0035133819     PISSN: 10217770     EISSN: 14230127     Source Type: Journal    
DOI: 10.1159/000054010     Document Type: Review

References (67)

1. Oligodendrocyte apoptosis and primary demyelination induced by local TNF/p55TNF receptor signaling in the central nervous system of transgenic mice: Models for multiple sclerosis with primary oligodendrogliopathy
2. Region-specific induction of ΔFosB by repeated administration of typical versus atypical antipsychotic drugs
3. Regional selectivity in ethanol-induced pro-oxidant events within the brain
4. Molecular mechanism of ethanol metabolism by human brain to fatty acid ethyl esters
5. Pathophysiology of alcoholic brain damage: Synergistic effects of ethanol, thiamin deficiency and alcoholic liver disease
6. Brain lesions in alcoholics
7. Differential expression of mitochondrial NADH dehydrogenase in ethanol-treated rat brain: Revealed by differential display
8. Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction
9. Biosynthesis and possible pathological significance of fatty acid ethyl esters
10. Profound decrement of mesolimbic dopaminergic neuronal activity during ethanol withdrawal syndrome in rats: Electrophysiological and biochemical evidence
11. A comparison of methodologies for the study of functional transmitter neurochemistry in human brain
12. Cell death mediated by amino acid transmitter receptors in human alcoholic brain damage: Conflicts in the evidence
13. PCR differential display identifies a rat brain mRNA that is transcriptionally regulated by cocaine and amphetamine
14. Increased expression of a mitochondrial gene in human alcoholic brain revealed by differential display
15. Drugs of abuse and stress increase the expression of GluR1 and NMDAR1 glutamate receptor subunits in the rat ventral tegmental area: Common adaptations among cross-sensitizing agents
16. The reaction of astrocytes and neurons in the hippocampus of adult rats during chronic ethanol treatment and correlations to behavioral impairments
17. In vivo actions of fibroblast growth factor-2 and insulin-like growth factor-I on oligodendrocyte development and myelination in the central nervous system
18. Ethanol regulation of adenosine receptor-stimulated cAMP levels in a clonal neural cell line: An in vitro model of cellular tolerance to ethanol
19. Alcohol, astroglia, and brain development
20. ESBRA 1994 Award Lecture. Phosphatidylethanol formation: Specific effects of ethanol mediated via phospholipase D
21. Insulin-like growth factors and binding proteins in multiple sclerosis plaques
22. Brain water in chronic alcoholics: A necropsy study
23. Neuropathological changes in alcoholics
24. Neuropathology of alcoholism
25. Brain shrinkage in chronic alcoholics: A pathological study
26. Role of acetaldehyde in the actions of ethanol on the brain: A review
27. Aetiology of alcoholic brain damage: Alcoholic neurotoxicity or thiamine malnutrition?
28. Expression of the transcription factor ΔFosB in the brain controls sensitivity to cocaine
29. Alterations and recovery of dendritic spine density in rat hippocampus following long-term ethanol ingestion
30. Drug addiction: The yin and yang of hedonic homeostasis
31. Neuroscience of addiction
32. The cerebral cortex is damaged in chronic alcoholics
33. Neuronal counts from four cortical regions of alcoholic brains
34. Presence of nonoxidative ethanol metabolism in human organs commonly damaged by ethanol abuse
35. A receptor in human alcoholic brain
36. Differential gene expression in the frontal cortex of human alcoholics
37. Sustained neonatal hyperthyroidism in the rat affects myelination in the central nervous system
38. Morphological alterations in rat CA1 hippocampal pyramidal cell dendrites resulting from chronic ethanol consumption and withdrawal
39. Low doses of ethanol inhibit the firing of neurons in the substantia nigra, pars reticulata: A GABAergic effect?
40. Alcohol's effects on gene expression
41. Molecular mechanisms of drug addiction
42. Molecular neurobiology of drug addiction
43. Molecular and cellular basis of addiction
44. Drug addiction: A model for the molecular basis of neural plasticity
45. Pharmacological studies of the regulation of chronic FOS-related antigen induction by cocaine in the striatum and nucleus accumbens
46. Induction of chronic Fos-related antigens in rat brain by chronic morphine administration
47. Brain gray and white matter volume loss accelerates with aging in chronic alcoholics: A quantitative MRI study
48. Longitudinal changes in magnetic resonance imaging brain volumes in abstinent and relapsed alcoholics
49. Increase in brain cerebrospinal fluid volume is greater in older than in younger alcoholic patients: A replication study and CT/MRI comparison
50. A quantitative histological study of the cerebellar vermis in alcoholic patients
51. Common neural substrates for the addictive properties of nicotine and cocaine
52. Abnormalities of the corpus callosum in children prenatally exposed to alcohol
53. Alcoholism: An introduction
54. 5-HT and alcohol abuse
55. Volumetric magnetic resonance imaging quantification of longitudinal brain changes in abstinent alcoholics
56. Ethanol-induced changes in insulin-like growth factors and IGF gene expression in the fetal brain
57. Gangliosides reduce the development of ethanol dependence without affecting ethanol tolerance
58. Effect of ethanol on the synthesis of insulin-like growth factor 1 (IGF-1) and the IGF-1 receptor in late prepubertal female rats: A correlation with serum IGF-1
59. Relationship between alcohol withdrawal seizures and temporal lobe white matter volume deficits
60. Magnetic resonance imaging of brain anomalies in fetal alcohol syndrome
61. Alcohol addiction: An enigma among us
62. Transmitter amino acid neurochemistry in chronic alcoholism with and without cirrhosis of the liver
63. Ethanol, thiamin and brain damage
64. Significant reversibility of alcoholic brain shrinkage within 3 weeks of abstinence
65. Ethanol exposure affects glial fibrillary acidic protein gene expression and transcription during rat brain development
66. Alcohol and cytokine-inducible transcription factors