Alcohol deters the outgrowth of serotonergic neurons at midgestation

Journal of Biomedical Science

Volumn 8, Issue 1, 2001, Pages 119-125

  Sari, Y ^a   Powrozek, T ^a   Zhou, F C ^a  

^a INDIANA UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Fetal alcohol effect; Fetal alcohol syndrome; Neural tube defect; Ontogeny; Teratology

Indexed keywords

SEROTONIN;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BRAIN DEVELOPMENT; CONTROLLED STUDY; DORSAL RAPHE NUCLEUS; FEMALE; FETAL ALCOHOL SYNDROME; FETUS; FOREBRAIN; IMAGE ANALYSIS; MALE; MEDIAN RAPHE NUCLEUS; MOUSE; NERVE PROJECTION; NEURAL TUBE DEFECT; NONHUMAN; ONTOGENY; PRENATAL EXPOSURE; PRIORITY JOURNAL; SEROTONINERGIC NERVE CELL; TERATOLOGY;

ANIMALS; BRAIN CHEMISTRY; EMBRYO; ETHANOL; FEMALE; FETAL ALCOHOL SYNDROME; GESTATIONAL AGE; IMMUNOHISTOCHEMISTRY; MALE; MEDIAL FOREBRAIN BUNDLE; MICE; MICE, INBRED C57BL; NEURONS; PREGNANCY; RAPHE NUCLEI; SEROTONIN;

EID: 0035133811     PISSN: 10217770     EISSN: 14230127     Source Type: Journal    
DOI: 10.1159/000054022     Document Type: Article

References (51)

1. S-100β but not NGF, EGF, insulin or calmodulin is a CNS serotonergic growth factor
2. The effects of prenatal alcohol exposure on odor associative learning in rats
3. Ethanol-induced reductions in cerebellar growth of infant rats
4. The effects of ethanol chronically administered to preweanling rats on cerebellar development: A morphological study
5. Possible role of 'prenervous' neurotransmitters in cellular interactions of early embryogenesis: A hypothesis
6. Prenatal alcohol exposure and human development
7. The effects of ethanol on developing catecholamine neurons
8. Serotonin initiates and autoamplifies its own synthesis during mouse central nervous system development
9. Effects of in utero ethanol exposure on the developing dopaminergic system in rats
10. Effects of in utero ethanol exposure on the developing serotonergic system
11. The effect of alcohol administration during pregnancy on the concentration of noradrenaline, dopamine and 5-hydroxytryptamine in the brain of offspring of mice
12. Effect of alcohol given at different periods of gestation on brain serotonin in offspring
13. Trophic effects of neurotransmitters during brain maturation
14. Effects of in utero ethanol exposure and maternal treatment with a 5-HT(1A) agonist on S100B-containing glial cells
15. 3H-vinylidene kainic acid binding in 45-day-old rats
16. Ethanol alters astrocyte development: A study of critical periods using primary cultures
17. Do serotonin and other neurotransmitters exert a trophic influence on the immature brain?
18. Maternal ethanol consumption: Binding of L-glutamate to synaptic membranes from whole brain, cortices, and cerebella of offspring
19. Ethanol neurotoxicity. I. Direct effect on replicating astrocytes
20. Protective effects of maternal buspirone treatment on serotonin reuptake sites in ethanol-exposed offspring
21. Disorders of brain development in the progeny of mothers who used alcohol during pregnancy
22. Impeded cerebellar development and reduced serum thyroxin levels associated with fetal alcohol intoxication
23. Increased aggressiveness and lower brain serotonin levels in offspring of mice given alcohol during gestation
24. Ontogeny of the serotonergic system in the rat: Serotonin as a developmental signal
25. Neurotransmitters as growth regulatory signals: Role of receptors and second messengers
26. Serotonin as a differentiation signal in early neurogenesis
27. Exposure of rats to ethanol from postnatal days 4 to 8: Alterations of cholinergic neurochemistry in the cerebral cortex and corpus striatum at day 20
28. S100β and insulin-like growth factor-II differentially regulate growth of developing serotonin and dopamine neurons in vitro
29. Fetal alcohol syndrome: A case report of neuropsychological, MRI, and EEG assessment of two children
30. A decrease in the size of the basal ganglia following prenatal alcohol exposure: A preliminary report
31. A decrease in the size of the basal ganglia in children with fetal alcohol syndrome
32. Development of histaminergic pathways in brain as influenced by maternal alcoholism
33. Effects of prolonged ethanol exposure on the glial fibrillary acidic protein-containing intermediate filaments of astrocytes in primary culture: A quantitative immunofluorescence and immunogold electron microscopic study
34. Brain perfusion SPECT and MRI in foetal alcohol syndrome
35. Altered development of brain by neonatal ethanol exposure: Zinc levels during and after exposure
36. Effects of fetal alcohol exposure on sizes and dimension of fetal forebrain in C57BL/6J mice
37. Development of neurotransmitter systems in the mouse embryo following acute ethanol exposure: A histological and immunocytochemical study
38. 1-histaminergic receptor binding dynamics
39. Prenatal effects of alcohol abuse in humans and laboratory animals
40. In utero ethanol exposure decreased the density of serotonin neurons: Maternal ipsapirone treatment exerted a protective effect
41. Development of the serotonergic system in the rat embryo: An immunochemical study
42. 1A receptors S-100 beta in development and plasticity
43. 1A receptors releases the serotonergic growth factor, protein S-100, and alters astroglial morphology
44. Fetal alcohol exposure alters serotonin transporter sites in rat brain
45. Quantitative immunocytochemical evaluation of serotonergic innervation in alcoholic rat brain
46. Mouse model of neural tube defect after fetal alcohol exposure
47. Prenatal alcohol exposure retards the migration and reduces the number of 5-HT neurons in fetal C57BL/6 mice
48. Prenatal alcohol exposure retards the migration and development of serotonin neurons in fetal C57BL/6J mice
49. Expression of serotonin transporter protein in developing rat brain