Prostacyclin inhibits the production of MMP-9 induced by phorbol ester through protein kinase A activation, but does not affect the production of MMP-2 in human cultured mesangial cells

Kidney and Blood Pressure Research

Volumn 24, Issue 1, 2001, Pages 18-26

  Kitahara, Masashi ^a   Ichikawa, Motoki ^a   Kinoshita, Tatsuya ^a   Shiozawa, Satoshi ^a   Shigematsu, Hidekazu ^a   Komiyama, Atsushi ^a  

^a SHINSHU UNIVERSITY SCHOOL OF MEDICINE   (Japan)

Author keywords

Glomerular sclerosis; Human cultured mesangial cells; Jun protein; MMP 2; MMP 9; Phorbol ester; Prostacyclin; Protein Kinase A

Indexed keywords

BERAPROST; CYCLIC AMP DEPENDENT PROTEIN KINASE; FORSKOLIN; GELATINASE A; GELATINASE B; N [2 (4 BROMOCINNAMYLAMINO)ETHYL] 5 ISOQUINOLINESULFONAMIDE; PHORBOL 13 ACETATE 12 MYRISTATE; PROSTACYCLIN; PROTEIN C JUN; TRANSCRIPTION FACTOR ETS 1;

ARTICLE; ENZYME ACTIVATION; EXTRACELLULAR MATRIX; GLOMERULOPATHY; HUMAN; HUMAN CELL; MESANGIUM CELL; PRIORITY JOURNAL; PROTEIN SYNTHESIS; PROTEIN SYNTHESIS INHIBITION; WESTERN BLOTTING; ZYMOGRAPHY;

CARCINOGENS; CELLS, CULTURED; CYCLIC AMP-DEPENDENT PROTEIN KINASES; ENZYME ACTIVATION; EPOPROSTENOL; GLOMERULAR MESANGIUM; HUMANS; MATRIX METALLOPROTEINASE 2; MATRIX METALLOPROTEINASE 9; PLATELET AGGREGATION INHIBITORS; SIGNAL TRANSDUCTION; TETRADECANOYLPHORBOL ACETATE;

EID: 0035132860     PISSN: 14204096     EISSN: None     Source Type: Journal    
DOI: 10.1159/000054201     Document Type: Article

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