Diseases of the digestive tract and telomere lengths: Significance and problems of telomere measurement

Japanese Journal of Gastroenterology

Volumn 98, Issue 2, 2001, Pages 144-150

  Takubo, K ^a   Kaminishi, M ^a  

^a TOKYO METROPOLITAN INSTITUTE OF GERONTOLOGY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

RNA DIRECTED DNA POLYMERASE; TELOMERASE;

ARTICLE; BARRETT ESOPHAGUS; DNA DEGRADATION; DYSPLASIA; GASTROINTESTINAL DISEASE; TELOMERE; TISSUE REGENERATION;

AGED; AGED, 80 AND OVER; DIGESTIVE SYSTEM DISEASES; ESOPHAGEAL NEOPLASMS; GASTRIC MUCOSA; HUMANS; INFANT, NEWBORN; INTESTINAL MUCOSA; METAPLASIA; TELOMERE;

EID: 0035116937     PISSN: 04466586     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (24)

1. The serial cultivation of human diploid cell strains
2. The limited in vitro lifetime of human diploid cell strains
3. The illusion of cell immortality
4. A highly conserved repetitive DNA sequence, (TTAGGG) n, present at the telomeres of human chromosomes
5. Telomeres shorten during ageing of human fibroblasts
6. Loss of telomeric DNA during aging of normal and trisomy 21 human lymphocytes
7. Telomere shortening with aging in human liver
8. Structure of the esophagus
9. Telomere shortening with aging in human esophageal mucosa
10. Telomere length, telomerase activity and telomerase RNA expression in human esophageal cancer cells: Correlation with cell proliferation, differentiation and chemosensitivity to anticancer drugs
11. Telomerase activity in esophageal carcinoma
12. Overexpression of human telomerase RNA is an early event in oesophageal carcinogenesis
13. Telomerase is active in normal gastrointestinal mucosa and not up-regulated in precancerous lesions
14. Telomerase activity in gastric cancer
15. Telomere length and telomerase activity in carcinogenesis of the stomach
16. Telomerase activity and its clinicopathological significance in gastric cancer
17. Telomere shortening in gastric carcinoma with aging despite telomerase activation
18. Telomerase activity in human intestine
19. Correlation of telomere lengths in normal and cancers tissue in the large bowel
20. Telomere shortening in the colonic mucosa of patients with ulcerative colitis
21. Telomere reduction in human colorectal carcinoma and with ageing
22. Telomere shortening and the clinicopathologic characteristics of human colorectal carcinomas
23. High telomerase activity is an independent prognostic indicator of poor outcome in colorectal cancer