Plant viral suppressors of post-transcriptional silencing do not suppress transcriptional silencing

Plant Journal

Volumn 22, Issue 1, 2000, Pages 51-59

  Marathe, Rajendra ^a   Smith, Trenton H ^a   Anandalakshmi, Radhamani ^a   Bowman, Lewis H ^a   Fagard, Mathilde ^b   Mourrain, Philippe ^b   Vaucheret, Hervé ^b   Vance, Vicki B ^a  

^a UNIVERSITY OF SOUTH CAROLINA   (United States)

^b CEMAGREF   (France)

Author keywords

[No Author keywords available]

Indexed keywords

2B GENE; CUCUMBER MOSAIC VIRUS; GENE ACTIVATION; GENE LOCUS; GENE SILENCING; NITRITE REDUCTASE GENE; PLANT POTYVIRUS; PROMOTER REGION; REVERSE TRANSCRIPTION; TOBACCO; TRANSCRIPTION TERMINATION; TRANSGENE; TRANSGENIC PLANT; VIRUS GENE;

CUCUMOVIRUS; GENE SILENCING; GENES, VIRAL; PLANT VIRUSES; PLANTS, GENETICALLY MODIFIED; PLANTS, TOXIC; POTYVIRUS; SUPPRESSION, GENETIC; TOBACCO; TRANSCRIPTION, GENETIC;

CUCUMBER MOSAIC VIRUS; CUCUMIS SATIVUS; EMBRYOPHYTA; NICOTIANA OBTUSIFOLIA; NICOTIANA TABACUM; POTYVIRUS;

EID: 0034017755     PISSN: 09607412     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1365-313X.2000.00710.x     Document Type: Article

References (42)

1. Anandalakshmi, R., Pruss, G., Ge, X., Marathe, R., Mallory, A.C., Smith, T.H. and Vance, V.B. (1998) A viral suppressor of gene silencing in plants. Proc. Natl Acad. Sci. USA, 95, 13079-13084.
2. Baulcombe, D. (1999) Viruses and gene silencing in plants. Arch. Virol. (Suppl.), 15, 189-201.
3. Béclin, C., Berthomé, R., Palaqui, J.C., Tepfer, M. and Vaucheret, H. (1998) Infection of tobacco or Arabidopsis plants by CMV counteracts systemic post-transcriptional silencing of nonviral (trans) genes. Virology, 252, 313-317.
4. Bingham, P.M. (1997) Cosuppression comes to the animals. Cell, 90, 385-387.
5. Brigneti, G., Voinnet, O., Li, W.-X., Ding, S.-W. and Baulcombe, D.C. (1998) Viral pathogenicity determinants are suppressor of transgene silencing in Nicotiana benthamiana. EMBO J. 17, 6739-6746.
6. Carrington, J.C., Freed, D.D. and Oh, C.-S. (1990) Expression of potyviral polyproteins in transgenic plants reveals three proteolytic activities required for complete processing. EMBO J. 9, 1347-1353.
7. Covey, S.N., Al-Kaff, N., Langara, A. and Turner, D.S. (1997) Plants combat infection by gene silencing. Nature, 38, 781-782.
8. De Mejia, M.V.G., Hiebert, E., Purcifull, D.E., Thornbury, D.W. and Pirone, T.P. (1985) Identification of potyviral amorphous inclusion protein as a nonstructural virus-specific protein related to helper component. Virology, 142, 34-43.
9. Depicker, A. and Van Montagu, M. (1997) Post-transcriptional gene silencing in plants. Curr. Opin. Cell Biol. 9, 373-382.
10. Ding, S.W., Anderson, B.J., Haase, H.R. and Symons, R.H. (1994) New overlapping gene encoded by the cucumber mosaic virus genome. Virology, 198, 593-601.
11. Elmayan, T., Balzerque, S., Beon, F. et al. (1998) Arabidopsis mutants impaired in cosuppression. Plant Cell, 10, 1747-1758.
12. Elmayan, T. and Vaucheret, H. (1996) Expression of single copies of a strongly expressed 35S transgene can be silenced post-transcriptionally. Plant J. 9, 787-797.
13. English, J.J., Mueller, E. and Baulcombe, D.C. (1996) Suppression of virus accumulation in transgenic plants exhibiting silencing of nuclear genes. Plant Cell, 8, 179-188.
14. Grant, S. (1999) Dissecting the mechanisms of posttranscriptional gene silencing: Divide and conquer. Cell, 96, 303-306.
15. Hobbs, S.L.A., Kpodar, P. and DeLong, C.M.O. (1990) The effect of T-DNA copy number, position and methylation on reporter gene expression in tobacco transformants. Plant Mol. Biol. 15, 851-864.
16. Ingelbrecht, I., Van Houdt, H., Van Montagu, M. and Depicker, A. (1994) Posttranscriptional silencing of reporter transgenes in tobacco correlates with DNA methylation. Proc. Natl Acad. Sci. USA, 91, 10502-10506.
17. Jakowitsch, J., Papp, I., van Moscone, E.A., der Winden, J., Matzke, M.A. and Matzke, A.J.M. (1999) Molecular and cytogenetic characterization of a transgene locus that induces silencing and methylation of homologous promoters in trans. Plant J. 17, 131-140.
18. Jones, L., Hamilton, A.J., Voinnet, O., Thomas, C.L., Maule, A.J. and Baulcombe, D.C. (1999) RNA-DNA interactions and DNA methylation in post-transcriptional gene silencing. Plant Cell, 11, 2291-2301.
19. Jones, A.L., Thomas, C.L. and Maule, A.J. (1998) De novo methylation and co-suppression induced by a cytoplasmically replicating plant RNA virus. EMBO J. 17, 6385-6393.
20. Kasschau, K.D. and Carrington, J.C. (1998) A counter-defensive strategy of plant viruses: suppression of post-transcriptional gene silencing. Cell, 95, 461-470.
21. Matzke, M.A. and Matzke, A.J.M. (1995) How and why do plants inactivate homologous (trans) genes? Plant Physiol. 107, 679-685.
22. Matzke, M.A. and Matzke, A.J.M. (1998) Epigenetic silencing of plant transgenes as a consequence of diverse cellular defense responses. Cell Mol. Life Sci. 54, 94-103.
23. Matzke, M.A., Matzke, A.J.M. and Eggleston, W.B. (1996) Paramutation and transgene silencing: a common response to invasive DNA? Trends Plant Sci. 1, 382-388.
24. Matzke, M.A., Primig, M., Trnovsky, J. and Matzke, A.J.M. (1989) Reversible methylation and inactivation of marker genes in sequentially transformed tobacco plants. EMBO J. 8, 643-649.
25. Mette, M.F., Winden, J.V.D., Matzke, M.A. and Matzke, A.J.M. (1999) Production of aberrant promoter transcripts contributes to methylation and silencing of unlinked homologous promoters in trans. EMBO J. 18, 241-248.
26. Meyer, P. (1995) Understanding and controlling transgene expression. Trends Biotech. 13, 332-337.
27. Otten, L.A. and Schilperoort, R.A. (1978) A rapid micro scale method for the detection of lysopine and nopaline dehydrogenase activities. Biochim. Biophys. Acta. 527, 497-500.
28. Palauqui, J.-C., Elmayan, T., Pollien, J.M. and Vaucheret, H. (1997) Systemic acquired silencing: transgene-specific post-transcriptional silencing is transmitted by grafting from silenced stocks to non-silenced scions. EMBO J. 16, 4738-4745.
29. Park, Y.D., Papp, I., Moscone, E.A., Iglesias, V.A., Vaucheret, H., Matzke, A.J.M. and Matzke, M.A. (1996) Gene silencing mediated by promoter homology occurs at the level of transcription and results in meiotically heritable alterations in methylation and gene activity. Plant J. 9, 183-194.
30. Pruss, G., Ge, X., Shi, X.M., Carrington, J.C. and Vance, V.B. (1997) Plant viral synergism: the potyviral genome encodes a broad-range pathogenicity enhancer that transactivates replication of heterologous viruses. Plant Cell, 9, 1-11.
31. Ratcliff, F., Harrison, B.D. and Baulcombe, D.C. (1997) A similarity between viral defense and gene silencing in plants. Science, 276, 1558-1560.
32. Ratcliff, F.G., MacFarlane, S.A. and Baulcombe, D.C. (1999) Gene silencing without DNA. RNA-mediated cross-protection between viruses. Plant Cell, 11, 1207-1216.
33. Riedel, D., Lesemann, D.-E. and Maiss, E. (1998) Ultrastructural localization of nonstructural and coat proteins of 19 potyviruses using antisera to bacterially expressed proteins of plum pox potyvirus. Arch. Virol. 143, 2133-2158.
34. Sijen, T., Wellink, J., Hiriart, J.-B. and Van Kammen, A. (1996) RNA-mediated virus resistance: role of repeated transgenes and delineation of targeted regions. Plant Cell, 8, 2277-2294.
35. Smith, H.A., Swaney, S.L., Parks, T.D., Wernsman, E.A. and Dougherty, W.G. (1994) Transgenic plant virus resistance mediated by untranslatable sense RNAs: expression, regulation, and fate of nonessentials RNAs. Plant Cell, 6, 1441-1453.
36. Stam, M., Viterbo, A., Mol, J.N. and Kooter, J.M. (1998) Position-dependent methylation and transcriptional silencing of transgenes in inverted T-DNA repeats: implications for posttranscriptional silencing of homologous host genes in plants. Mol. Cell Biol. 18, 6165-6177.
37. Thierry, D. and Vaucheret, H. (1996) Sequence homology requirements for transcriptional silencing of 35S transgenes and post-transcriptional silencing of nitrite reductase (trans) genes by the tobacco 271 locus. Plant Mol. Biol. 32, 1075-1083.
38. Vaucheret, H. (1993) Identification of a general silencer for 19S and 35S promoters in a transgenic tobacco plant: 90 bp of homology in the promoter sequence are sufficient for translnactivation. C. R. Acad. Sci. Paris, 316, 1471-1483.
39. Vaucheret, H., Béclin, C., Elmayan, T., Feuerbach, F., Godon, C., Morel, J.B., Mourrain, P., Palaqui, J.C. and Vernhettes, S. (1998) Transgene-induced gene silencing in plants. Plant J. 16, 651-659.
40. Voinnet, O. and Baulcombe, D.C. (1997) Systemic signaling in gene silencing. Nature, 389, 553.
41. Voinnet, O., Pinto, Y.M. and Baulcombe, D.C. (1999) Suppression of gene silencing: a general strategy used by diverse DNA and RNA viruses of plants. Proc. Natl Acad. Sci. USA, 96, 14147-14152.
42. Wassenegger, M. and Pelissier, T. (1998) A model for RNA-mediated gene silencing in higher plants. Plant Mol. Biol. 37, 349-362.