Random mutagenesis-PCR to introduce alterations into defined DNA sequences for validation of SNP and mutation detection methods

Human Mutation

Volumn 17, Issue 3, 2001, Pages 210-219

  Nickerson, Michael L ^a   Warren, Michelle B ^a   Zbar, Berton ^a   Schmidt, Laura S ^a  

^a NATIONAL CANCER INSTITUTE   (United States)

Author keywords

DHPLC; MET proto oncogene; Mutation detection; PCR; Random mutagenesis; Sequencing; Signature; Single nucleotide polymorphism; SNP

Indexed keywords

DNA POLYMERASE; PROTEIN TYROSINE KINASE;

ALGORITHM; ARTICLE; CALCULATION; CARCINOGENESIS; CLINICAL ARTICLE; DNA DENATURATION; DNA SEQUENCE; EXON; GENE DELETION; GENE MUTATION; GENETIC VARIABILITY; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HUMAN; KIDNEY CARCINOMA; MOLECULAR CLONING; MUTAGENESIS; NUCLEIC ACID BASE SUBSTITUTION; NUCLEOTIDE SEQUENCE; PAPILLARY CARCINOMA; POLYMERASE CHAIN REACTION; PREDICTION; PRIORITY JOURNAL; PROTO ONCOGENE; RELIABILITY; SAMPLE; SEQUENCE ANALYSIS; SINGLE NUCLEOTIDE POLYMORPHISM;

CHROMATOGRAPHY, HIGH PRESSURE LIQUID; CLONING, MOLECULAR; DNA; DNA MUTATIONAL ANALYSIS; EXONS; HUMANS; MUTAGENESIS; MUTATION; POLYMERASE CHAIN REACTION; POLYMORPHISM, SINGLE NUCLEOTIDE; PROTO-ONCOGENE PROTEINS C-MET; SEQUENCE ANALYSIS, DNA;

EID: 0035112279     PISSN: 10597794     EISSN: None     Source Type: Journal    
DOI: 10.1002/humu.6     Document Type: Article

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