Novel mutation in the atp-binding site of the met oncogene tyrosine kinase in a hprcc family

International Journal of Cancer

Volumn 82, Issue 5, 1999, Pages 640-643

  Olivero, Martina ^a,b   Valente, Guido ^b,c   Bardelli, Alberto ^a,b   Longati, Paola ^a,b   Ferrero, Norma ^a,b   Cracco, Cecilia ^b   Terrone, Carlo ^b   Rocca Rossetti, Salvatore ^b   Comoglio, Paolo M ^a,b   Di Renzo, M Flavia ^a,b  

^a CANDIOLO CANCER INSTITUTE   (Italy)

^b UNIVERSITY OF TURIN   (Italy)

^c UNIVERSITY OF EASTERN PIEDMONT   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

ADENOSINE TRIPHOSPHATE; COMPLEMENTARY DNA; SCATTER FACTOR RECEPTOR; PROTEIN TYROSINE KINASE;

ARTICLE; BINDING SITE; CELL TRANSFORMATION; FEMALE; GENETICS; HUMAN; KIDNEY CARCINOMA; KIDNEY TUMOR; MALE; METABOLISM; MUTATION; PATHOLOGY; PEDIGREE; ADULT; AGED; CANCER SUSCEPTIBILITY; CELL STRAIN 3T3; CLINICAL ARTICLE; ENZYME ACTIVATION; KIDNEY PAPILLA; MISSENSE MUTATION; ONCOGENE; PRIORITY JOURNAL; PROTEIN DOMAIN;

ADENOSINE TRIPHOSPHATE; BINDING SITES; CARCINOMA, RENAL CELL; CELL TRANSFORMATION, NEOPLASTIC; DNA, COMPLEMENTARY; FEMALE; GERM-LINE MUTATION; HUMANS; KIDNEY NEOPLASMS; MALE; PEDIGREE; PROTO-ONCOGENE PROTEINS C-MET;

EID: 0033609670     PISSN: 00207136     EISSN: None     Source Type: Journal    
DOI: 10.1002/(sici)1097-0215(19990827)82:5<640::aid-ijc4>3.0.co;2-6     Document Type: Article

References (20)

1. BARDELLI, A., LONGATI, P., GRAMAGLIA, D., BASILICO, C., TAMAGNONE, L., GIORDANO, S., BALLINARI, D., MICHIELI, P. and COMOGLIO, P.M., Uncoupling signal transducers from oncogenic MET mutants abrogates cell transformation and inhibits invasive growth. Proc. nat. Acad. Sci. (Wash.), 95, 14379-14383 (1998).
2. BOSSEMEYER, D., The glycine-rich sequence of protein kinases: a multifunctional element. Trends Biochem. Sci., 19, 201-205 (1994).
3. COTTRELL, S., BICKNELL, D., KAKLAMANIS, L. and BODMER, W.F., Molecular analysis of APC mutations in familial adenomatous polyposis and sporadic colon carcinomas. Lancet, 340, 626-630 (1992).
4. DELAHUNT, B. and EBLE, J.N., Papillary renal-cell carcinoma: a clinicopathologic and immunohistochemical study of 105 tumors. Mod. Pathol., 10, 537-544 (1997).
5. GOLDBERG, I.D. and ROSEN, E.M., Hepatocyte-growth-factor-scatter-factor (HGF-SF) and the c-Met receptor, Birkhauser, Berlin (1993).
6. HANKS, S.K., QUINN, A.M. and HUNTER, T., The protein-kinase family: conserved features and deduced phylogeny of the catalytic domains. Science, 241, 42-52 (1988).
7. JEFFERS, M., SCHMIDT, L., NAKAIGAWA, N., WEBB, C.P., WEIRICH, G., KISHIDA, T., ZBAR, B. and VAN DE WOUDE, G.F., Activating mutations for the met tyrosine-kinase receptor in human cancer. Proc. nat. Acad. Sci. (Wash.), 94, 11445-11450 (1997).
8. KOVACS, G., Molecular cytogenetics of renal-cell tumors. Advanc. Cancer Res., 62, 89-124 (1993).
9. KOVACS, G. and 18 OTHERS, The Heidelberg classification of renal-cell tumours. J. Pathol., 183, 131-133 (1997).
10. LEE, J.H., MAEDA, S., ANGELOS, K.L., KAMITA, S.G., RAMACHANDRAN, C. and WALSH, D.A., Analysis by mutagenesis of the ATP-binding site of the gamma sub-unit of skeletal-muscle phosphorylase kinase expressed using a baculovirus system. Biochemistry; 31, 10616-10625 (1992).
11. NAGAIKE, M., HIRAO, S., TATIMA, H., NOJI, S., TANIGUCHI, S., MATSUMOTO, K. and NAKAMURA, T., Renotropic functions of hepatocyte growth factor in renal regeneration after unilateral nephrectomy. J. biol. Chem., 266, 22781-22784 (1991).
12. NATALI, P.G., PRAT, M., NICOTRA, M.R., BIGOTTI, A., OLIVERO, M., COMOGLIO, P.M. and DI RENZO, M.F., Over-expression of the met/HGF receptor in renal-cell carcinomas. Int. J. Cancer, 69, 212-217 (1996).
13. PONZETTO, C., GIORDANO, S., PEVERALI, F., DELLA VALLE, G., ABATE, M.L., VAULA, G. and COMOGLIO, P.M., c-met is amplified but not mutated in a cell line with an activated met tyrosine-kinase. Oncogene, 6, 553-559 (1991).
14. RODRIGUES, G.A., NAUJOKAS, M.A. and PARK, M., Alternative splicing generates isoforms of the met-receptor tyrosine kinase which undergo differential processing. Mol. cell. Biol., 11, 2962-2970 (1991).
15. SCHMIDT, L. and 24 OTHERS, Germline and somatic mutations in the tyrosine-kinase domain of the MET proto-oncogene in papillary renal carcinomas. Nature Genet., 16, 68-73 (1997).
16. SHU, H.K., PELLEY, R.J. and KUNG, H.J., Tissue-specific transformation by epidermal-growth-factor receptor: a single point mutation within the ATP-binding pocket of the erbB product increases its intrinsic kinase activity and activates its sarcomagenic potential. Proc. nat. Acad. Sci. (Wash.), 87, 9103-9107 (1990).
17. WETERMAN, M.A., WILBRINK, M. and GEURTS VAN KESSEL, A., Fusion of the transcription factor TFE3 gene to a novel gene, PRCC, in t(X;1)(p11;q21)-positive papillary renal-cell carcinomas. Proc. nat. Acad. Sci. (Wash.). 93, 15294-15298 (1996).
18. WOOLF, A.S., KOLATSI-JOANNOU, M., HARDMAN, P., ANDERMARCHER, E., MOORBY, C., FINE, L.G., JAT, P.S., NOBLE, M.D. and GHERARDI, E., Roles of hepatocyte growth factor/scatter factor and the met receptor in the early development of the metanephros. J. Cell Biol., 128, 171-184 (1995).
19. ZBAR, B., Von Hippel-Lindau disease and sporadic renal-cell carcinoma. Cancer Surv., 25, 219-232 (1995).
20. ZBAR, B. and LERMAN, M., Inherited carcinomas of the kidney. Adv. Cancer Res., 75, 163-201 (1998).