Human osteoclast cathepsin K is processed intracellularly prior to attachment and bone resorption

Journal of Bone and Mineral Research

Volumn 16, Issue 3, 2001, Pages 478-486

  Dodds, Robert A ^a   James, Ian E ^a   Rieman, David ^a   Ahern, Reina ^a   Hwang, Shing Mei ^a   Connor, Janice R ^a   Thompson, Scott D ^a   Veber, Daniel F ^a   Drake, Fred H ^a   Holmes, Stephen ^a   Lark, Michael W ^a   Gowen, Maxine ^a  

^a GLAXOSMITHKLINE   (United Kingdom)

Author keywords

Cathepsin K processing; Cytochemistry; Osteoclast; Ruffled border

Indexed keywords

CATHEPSIN K; CYSTEINE PROTEINASE; MESSENGER RNA; PAPAIN;

ARTICLE; ENZYME ACTIVITY; HUMAN; HUMAN CELL; IMMUNOHISTOCHEMISTRY; IMMUNOREACTIVITY; OSTEOCLAST; OSTEOCLASTOMA; OSTEOLYSIS; PROTEIN EXPRESSION;

BIOCHEMISTRY; BONE AND BONES; BONE RESORPTION; CATHEPSINS; CELL ADHESION; CYSTEINE PROTEINASE INHIBITORS; GIANT CELL TUMOR OF BONE; HUMANS; HYDROGEN-ION CONCENTRATION; KIDNEY; LEUCINE; LINEAR MODELS; OLIGOPEPTIDES; OSTEOCLASTS; PEPSTATINS; PHENYLMETHYLSULFONYL FLUORIDE; PROTEASE INHIBITORS; PROTEIN PROCESSING, POST-TRANSLATIONAL; SUBSTRATE SPECIFICITY; TUMOR CELLS, CULTURED;

EID: 0035109071     PISSN: 08840431     EISSN: None     Source Type: Journal    
DOI: 10.1359/jbmr.2001.16.3.478     Document Type: Article

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