Genetic epidemiology of primary osteoerthritis

Current Opinion in Rheumatology

Volumn 13, Issue 2, 2001, Pages 111-116

  Loughlin, John ^a  

^a UNIVERSITY OF OXFORD   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

AGGRECAN; COLLAGEN TYPE 1; COLLAGEN TYPE 11; COLLAGEN TYPE 2; COLLAGEN TYPE 9; ESTROGEN RECEPTOR; PROTEIN; SOMATOMEDIN C; TRANSFORMING GROWTH FACTOR BETA1; VITAMIN D RECEPTOR;

CHROMOSOME; GENE; GENETIC EPIDEMIOLOGY; GENETIC LINKAGE; GENETIC SUSCEPTIBILITY; HUMAN; OSTEOARTHRITIS; PRIORITY JOURNAL; REVIEW; SIBLING; TWINS;

DISEASES IN TWINS; FEMALE; GENES; HUMANS; LINKAGE (GENETICS); MALE; NUCLEAR FAMILY; OSTEOARTHRITIS; RISK FACTORS; TWIN STUDIES;

EID: 0035092827     PISSN: 10408711     EISSN: None     Source Type: Journal    
DOI: 10.1097/00002281-200103000-00004     Document Type: Review

References (39)

1. Genetic influences on osteoarthritis in women: A twin study
2. The genetic contribution to radiographic hip osteoarthritis: A population-based twin study
3. Genetic liability to osteoarthritis may be greater in women than men
4. Twins and the genetic architecture of osteoarthritis
5. Genetic influences in end-stage osteoarthritis: Sibling risks of hip and knee replacement for idiopathic osteoarthritis
6. Familial aggregation of osteoarthritis: Data from the Baltimore longitudinal study on aging
7. Evidence for a Mendelian gene in a segregation analysis of generalized radiographic osteoarthritis
8. Heritabilities of radiologic osteoarthritis in peripheral joints and of disc degeneration of the spine
9. Genetic linkage analysis of 14 candidate gene loci in a family with autosomal dominant osteoarthritis without dysplasia
10. Autosomal dominant (Beukes) premature degenerative osteoarthropathy of the hip joint maps to an 11-cM region on chromosome 4q35
11. Sibling pair analysis shows no linkage of generalized osteoarthritis to the loci encoding type II collagen (COL2A1), cartilage link protein (CRTL1) or cartilage matrix protein (CRTM)
12. Linkage analysis of candidate genes as susceptibility loci for osteoarthritis: Suggestive linkage of COLgA1 to female hip osteoarthritis
13. Association of two loci on chromosome 2q with nodal osteoarthritis
14. Genome scan for predisposing loci for distal interphalangeal joint osteoarthritis: Evidence for a locus on 2q
15. Osteoarthritis-susceptibility locus on chromosome 11q, detected by linkage
16. Stratification analysis of an osteoarthritis genome screen: Suggestive linkage to chromosomes 4, 6 and 16
17. Linkage analysis of chromosome 2q in osteoarthritis
18. Osteoarthritis and cartilage collagen genes
19. Haplotype analysis of three polymorphisms of the COL2A1 gene and associations with generalized radiologic osteoarthritis
20. Association of early osteoarthritis of the knee with a Taql polymorphism of the vitamin D receptor gene
21. Vitamin D receptor genotype is associated with radiographic osteoarthritis at the knee
22. Adjacent genes, for COL2A1 and the vitamin D receptor, are associated with separate features of radiographic osteoarthritis of the knee
23. Osteoarthritis of the spine: Association with bone density in the hip, not with gene polymorphism of the vitamin D receptor or collagen-1
24. Lack of association between osteoarthritis of the hip and gene polymorphisms of VDR, COL1A1 and COL2A1 in postmenopausal women
25. Association analysis of the vitamin D receptor gene, the type 1 collagen gene COL1A1 and the estrogen receptor gene in idiopathic osteoarthritis
26. Multiallelic polymorphism of the cartilage collagen gene: No association with osteoarthrosis
27. Differential allelic expression of the type II collagen gene (COL2A1) in osteoarthritic cartilage
28. A population-based study of the genetics of osteoarthritis
29. Array-based candidate gene analysis identify COL11A2 on 6p21.3 as predisposing locus for distal interphalangeal joint osteoarthritis
30. An association between an aggrecan polymorphic allele and bilateral hand osteoarthritis in elderly white men: Data from the Baltimore Longitudinal Study of Aging (BLSA)
31. Association between an aggrecan gene polymorphism and lumbar disc degeneration
32. Investigation of the association of the CRTM and CRTL1 genes with radiographically evident osteoarthritis in subjects from the Rotterdam study
33. Analysis of the association of the matrillin-1 gene (CRTM) with osteoarthritis
34. Allelic variation in the vitamin D receptor, lifestyle factors and lumbar spinal degenerative disease
35. Intragenic polymorphisms of the vitamin D receptor gene associated with intervertebral disc degeneration
36. Vitamin D receptor polymorphisms and osteoarthritis of the hand, hip, and knee: A case-control study in Japan
37. Estrogen receptor gene polymorphism and generalized osteoarthritis
38. A genetic association study of the IGF-1 gene and radiologic osteoarthritis in a population-based cohort study (the Rotterdam study)
39. 10Pro polymorphism of the transforming growth factor β1 with genetic susceptibility to osteoporosis and spinal osteoarthritis