Medullary serotonergic network deficiency in the sudden infant death syndrome: Review of a 15-year study of a single dataset

Journal of Neuropathology and Experimental Neurology

Volumn 60, Issue 3, 2001, Pages 228-247

  Kinney, Hannah C ^a   Filiano, James J ^b   White, W F ^c  

^a BOSTON CHILDREN S HOSPITAL   (United States)

^b CHILDREN S HOSPITAL AT DARTMOUTH   (United States)

^c PFIZER GLOBAL RESEARCH AND DEVELOPMENT   (United States)

Author keywords

Arcuate nucleus of the medulla oblongata; Autonomic control; Caudal raph ; Chemoreception; Receptor autoradiography; Serotonin; Sudden infant death

Indexed keywords

ARCUATE NUCLEUS; ARTICLE; ASPHYXIA; HOMEOSTASIS; HUMAN; HYPERCAPNIA; HYPOXIA; INFANT; NERVE CELL NETWORK; PRIORITY JOURNAL; RETICULAR FORMATION; SEROTONINERGIC NERVE CELL; SEROTONINERGIC SYSTEM; SUDDEN INFANT DEATH SYNDROME; SUPINE POSITION;

EID: 0035091031     PISSN: 00223069     EISSN: None     Source Type: Journal    
DOI: 10.1093/jnen/60.3.228     Document Type: Article

References (74)

1. Defining the sudden infant death syndrome (SIDS): Deliberations of an expert panel convened by the National Institute of Child Health Human Development
2. CO2, brainstem chemoreceptors and breathing
3. 8-OH-DPAT-sensitive neurons in the nucleus raphé magnus modulate thermoregulatory output in rats
4. Abnormal phrenic motoneuron activity and morphology in neonatal monoamine oxidase A-deficient transgenic mice: Possible role of a serotonin excess
5. Bulbospinal serotonergic pathways in the control of blood pressure
6. Role of the medullary raphé nuclei in the respiratory response to CO2
7. Somatodendritic and axonal anatomy of intracellularly labeled serotonergic neurons in the rat medulla
8. Caudal midline medulla mediates behaviourally-coupled but not baroreceptor-mediated vasodepression
9. Changes in serotonin metabolism may elicit obstructive apnoea in the newborn rat
10. Serotonin-mediated excitation of recurrent laryngeal and phrenic motoneurons evoked by stimulation of the raphé obscurus
11. Origin of serotonin-containing projections to the ventral respiratory group in the rat
12. Localization of the cardiovascular effects of 8-OH-DPAT at the ventral surface of the medulla
13. Origin of serotoninergic afferents to the hypoglossal nucleus in the rat
14. RVLM and raphé differentially regulate sympathetic outflows to splanchnic and brown adipose tissue
15. Involvement of the raphé in the respiratory effects of gigantocellular area activation
16. Sudden Infant Death Syndrome: The role of central chemosensitivity
17. The neuropathology of the sudden infant death syndrome. A review
18. A perspective on neuropathologic findings in victims of the sudden infant death syndrome: The triple-risk model
19. Decreased muscarinic receptor binding in the arcuate nucleus in sudden infant death syndrome
20. Brainstem 3H-nicotine receptor binding in the sudden infant death syndrome
21. Decreased kainate receptor binding in the arcuate nucleus of the sudden infant death syndrome
22. Differential expression of glutamate receptor subtypes in human brainstem sites involved in perinatal hypoxia-ischemia
23. Alpha2-adrenergic receptor binding in the medulla oblongata in the sudden infant death syndrome
24. Tritiated-naloxone binding to brainstem opioid receptors in the sudden infant death syndrome
25. Three-dimensional distribution of 3H-naloxone binding to opiate receptors in the human fetal and infant brainstem
26. Developmental changes in [3H]lysergic acid diethylamide ([3H]LSD) binding to serotonin receptors in the human brainstem
27. Three-dimensional distribution of [3H]quinuclidinyl benzilate binding to muscarinic cholinergic receptors in the developing human brainstem
28. 3-Dimensional anatomic relationship of serotonergic and muscarinic receptor binding in the pontine reticular formation of the human infant brainstem
29. Three-dimensional autoradiographic localization of quench-corrected glycine receptor specific activity in the mouse brain using 3H-strychnine as the ligand
30. Developmental changes in [3H]kainate binding in human brainstem sites vulnerable to perinatal hypoxia-ischemia
31. Early developmental changes in [3H]nicotine binding in the human brainstem
32. Distribution of alpha2-adrenergic receptor binding in the developing human brainstem
33. Decreased serotonergic receptor binding in rhombic lip derived regions of the medulla oblongata in the sudden infant death syndrome
34. Developmental changes in heterogeneous patterns of neurotransmitter receptor binding in the human interpeduncular nucleus
35. Early developmental changes in the chemoarchitecture of the human inferior olive: A review
36. Developmental changes in neurotransmitter receptor binding in the human periaqueductal gray
37. Anatomic and neurochemical studies of the human ventral medulla in early life: Observations relevant to the sudden infant death syndrome
38. Abnormal regulation of ventilation in infants at risk for sudden-infant-death syndrome
39. Candidate cell populations for respiratory chemosensitive fields in the human infant medulla
40. Primary alveolar hypoventilation (Ondine's curse syndrome) in an infant without external arcuate nucleus. Case report
41. Arcuate nucleus hypoplasia in the sudden infant death syndrome
42. Loss of central chemosensitivity. Experimental studies on a clinical problem
43. Localization of putative neural respiratory regions in the human by functional magnetic resonance imaging
44. Anatomic relationships of the human arcuate nucleus of the medulla: A Dil-labeling study
45. Studies of neuroregulators in the brain stem of SIDS
46. Changes in cerebrospinal fluid monoamine metabolites, tryptophan, and gamma-aminobutyric acid during the 1st year of life in normal infants. Comparison with victims of sudden infant death syndrome
47. Neurotransmission and sudden infant death. Study of cerebrospinal fluid. Comptes Rendus de 1 Academie des Sciences - Serie lii
48. Cell migrations from the rhombic lip to the inferior olive, the nucleus raphé and the pons: A morphological and experimental investigation on chick embryos
49. Immunohistochemical study of the development of serotonergic neurons in the rat CNS
50. Severe hypoplasia of medullary arcuate nucleus: Quantitative analysis in sudden infant death syndrome
51. Reduction in choline acetyltransferase immunoreactivity but not muscarinic-m2 receptor immunoreactivity in the brainstem of SIDS infants
52. Immunohistochemical studies on neuronal changes in brain stem nucleus of forensic autopsied cases. II. Sudden infant death syndrome
53. Cerebellar cortex delayed maturation in sudden infant death syndrome
54. Raphe nuclei and the serotonergic system
55. GATA-3 is involved in the development of serotonergic neurons in the caudal raphé nuclei
56. Projections of the dorsal raphé nucleus to the brainstem: PHA-L analysis in the rat
57. The role of brain serotonin. A neurophysiologic perspective
58. Effects of serotonin on caudal raphé neurons: Inhibition of N-and P/Q-type calcium channels and the afterhyperpolarization
59. Brainstem projections to the major respiratory neuron populations in the medulla of the cat
60. Response of serotonergic caudal raphé neurons in relation to specific motor activities in freely moving cats
61. Effect of activation of 5-HT1A receptors at the ventral medulla on phrenic nerve activity
62. Distribution of serotonin-containing cell bodies in the brainstem of the human fetus determined with immunohistochemistry using antiserotonin serum
63. Development of the human medullary serotonergic system in early life
64. Sleep influences on homeostatic functions: Implications for sudden infant death syndrome
65. Finding the failure mechanism in sudden infant death syndrome
66. Cardiorespiratory recordings from infants dying suddenly and unexpectedly at home
67. 'Reactive gliosis' in the medulla oblongata of victims of the sudden infant death syndrome
68. The amount of brainstem gliosis in sudden infant death syndrome (SIDS) victims correlates with maternal cigarette smoking during pregnancy
69. Cell bodies of origin of serotonin-immunoreactive afferents to the inferior olivary complex of the rat
70. Serotonin modulation of inferior olivary oscillations and synchronicity: A multiple-electrode study in the rat cerebellum
71. Development of the human central nervous system
72. The development of nuclei pontis and nucleus arcuatus in man