Glutamine: A life-threatening deficiency in the critically ill?

Intensive Care Medicine

Volumn 27, Issue 1, 2001, Pages 12-15

  Griffiths, R D ^a   Andrews, F ^a  

^a UNIVERSITY OF LIVERPOOL   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

ASCORBIC ACID; GLUTAMIC ACID; GLUTAMINE; HYDROCORTISONE;

AMINO ACID METABOLISM; BURN; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; CRITICAL ILLNESS; EDITORIAL; HIGH RISK PATIENT; HOST RESISTANCE; HUMAN; INFECTION; INTENSIVE CARE UNIT; MAJOR CLINICAL STUDY; MULTICENTER STUDY; MULTIPLE ORGAN FAILURE; NUTRITIONAL DEFICIENCY; NUTRITIONAL SUPPORT; SCURVY; STRESS; TOTAL PARENTERAL NUTRITION;

ANIMALS; BURNS; DIET THERAPY; GLUTAMINE; HUMANS; SEPSIS;

EID: 0035089383     PISSN: 03424642     EISSN: None     Source Type: Journal    
DOI: 10.1007/s001340000753     Document Type: Editorial

References (36)

1. The synthesis of glutamine from glutamic acid and ammonia and the enzymatic hydrolysis of glutamine in animal tissues
2. Oxidation of glutamine by the splanchnic bed in humans
3. Intestinal glutamate metabolism
4. Influence of the postoperative state on the intracellular free amino acids in human muscle tissue
5. Accelerated glutamine synthesis in critically ill patients cannot maintain normal intracellular free glutamine concentrations
6. Characteristics of L-glutamine transport in perfused rat muscle
7. Muscle glutamine depletion after major orthopaedic surgery can be attenuated by im-mediate postoperative spontaneous food intake
8. The metabolic consequences of critical illness: Acute effects on glutamine and protein metabolism
9. Effects of glutamine supplementation, GH, and IGF-1 on glutamine metabolism in critically ill patients
10. Deficiency in peripheral glutamine production in paediatric patients with bums
11. Inhibition of muscle glutamine formation in hypercatabolic patients
12. Glutamine supplementation to ICU patients affects lactate metabolism in skeletal muscle
13. Glutathione status in critially-ill patients: Possibility of modulation by antioxidants
14. Skeletal muscle glutathione is depleted in critically ill patients
15. Influence of entral diets supplemented with key nutrients on lymphocyte subpopulations in Peyer's patches of endotoxin-boostered mice
16. Glutamine protects U937 cells against heat-induced apoptosis in association with high expression of hsp70
17. Glutamine protects intestinal epithelial cells: Role of inducible HSP70
18. Heat shock protein induction in heart and lung tissue after glutamine infusion
19. Glutamine and the immune system
20. Dietary glutamine enhances murine T-lymphocyte responsiveness
21. Glutamine enriched parenteral nutrition improves splenocyte interferon-gamma production
22. Lymphocyte proliferation modulated by glutamine: Involved in the endogenous redox reaction
23. Splanchnic bed utilisation of glutamine and glutamic acid in humans
24. Glycyl-L-glutamine-enriched total parenteral nutrition maintains small intestine gut-associated lymphoid tissue and upper respiratory tract immunity
25. Postoperative glutamin-dipeptide infusion prevents the decrease of HLA-DR expression on monocytes unduced by surgery
26. Glutamine-supplemented total parenteral nutrition reduces blood mononuclear cell interleukin-8 release in severe acute pancreatitis
27. Total parenteral nutrition with glutamine dipeptide after major abdominal surgery - A randomized, double-blind, controlled study
28. Plasma glutamine depletion and patients outcome in acute ICU admissions
29. Glutamine: A necessary nutrient for the intensive care patient
30. Glutamine: Establishing clinical indications
31. Effects of supplemental parenteral L-alanyl-L-glutamine (ALA-GLN) following elective operations: A European multicenter study
32. The impact of alanyl-glutamine on clinical safety, nitrogen balance, intestinal permeability, and clinical outcome in postoperative patients: A randomized, doubleblind, controlled study of 120 patients
33. Influence of glutamine enriched parenteral nutrition on nitrogen balance and immunological status in patients undergoing elective aortic aneurysms repair
34. Glutamine supplemented TPN in major abdominal surgery
35. Six-month outcome of critically ill patients given glutamine supplemented parental nutrition
36. GlutamineTPN and intensive care acquired infections