N(G)-monomethyl-L-arginine alters insulin-mediated calf blood flow but not glucose disposal in the elderly

Metabolism: Clinical and Experimental

Volumn 50, Issue 3, 2001, Pages 306-310

  Meneilly, Graydon S ^a,b,c   Elliott, Thomas ^a,b,c   Battistini, Bruno ^a,b,c   Floras, John S ^a,b,c  

^a UNIVERSITY OF BRITISH COLUMBIA   (Canada)

^b LAVAL UNIVERSITY   (Canada)

^c UNIVERSITY OF TORONTO   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

GLUCOSE; INSULIN; N(G) METHYLARGININE; NITRIC OXIDE; NITRIC OXIDE SYNTHASE INHIBITOR;

ADOLESCENT; ADULT; AGING; ARTICLE; BLOOD FLOW; BLOOD PRESSURE; CLINICAL ARTICLE; CLINICAL TRIAL; CONDUCTANCE; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DRUG EFFECT; FEMALE; GASTROCNEMIUS MUSCLE; GERIATRICS; GLUCOSE BLOOD LEVEL; GLUCOSE TRANSPORT; HUMAN; HYPOTHESIS; INSULIN BLOOD LEVEL; INSULIN INFUSION; INSULIN RESISTANCE; MALE; MEAN ARTERIAL PRESSURE; NONHUMAN; PRIORITY JOURNAL; RANDOMIZED CONTROLLED TRIAL; SKELETAL MUSCLE; VASODILATATION; VEIN OCCLUSION PLETHYSMOGRAPHY;

EID: 0035084458     PISSN: 00260495     EISSN: None     Source Type: Journal    
DOI: 10.1053/meta.2001.19493     Document Type: Article

References (28)

1. Insulin-induced vasodilation: Physiology or pharmacology?
2. Insulin and the vasculature - Old actors, new roles
3. Characterization of the insulin resistance of aging
4. Mechanisms of the insulin resistance of aging
5. Glucose intolerance and aging: Evidence for tissue insensitivity to insulin
6. Insulin action in aging man: Evidence for tissue-specific differences at low physiologic insulin levels
7. Effect of age on kinetics of nitric oxide release in rat oarta and pulmonary artery
8. Insulin-mediated increase in blood flow is impaired in the elderly
9. Manual feedback technique for control of glucose concentration
10. Effects of arterial versus venous sampling on analysis of glucose kinetics in man
11. NIDDM in the elderly
12. Resistance or conductance for expression of arterial vascular tone
13. Should clinical cardiologists report total peripheral resistance or total peripheral conductance?
14. Glucose clamp technique: A method for quantifying insulin secretion and resistance
15. Assessment of insulin sensitivity in older adults using the hyperglycemic clamp technique
16. Angiotensin II increases glucose utilization during acute hyperinsulinemia via a hemodynamic mechanism
17. Role of nitric oxide in isoprenaline and sodium nitroprusside-induced relaxation in human hand veins
18. 18F] fluoro-deoxy-glucose and positron emission tomography
19. Insulin resistance of glucose uptake in skeletal muscle cannot be ameliorated by enhancing endothelium-dependent blood flow in obesity
20. Vascular effects of acute hyperglycemia in humans are reversed by L-arginine
21. L-Arginine but not D-arginine stimulates insulin-mediated glucose uptake
22. Lack of effect of sodium nitroprusside on insulin-mediated blood flow and glucose disposal in the elderly
23. Systemic nitric oxide synthase inhibition increases insulin sensitivity in man
24. Effects of age and body fat on insulin resistance in healthy men
25. Contrasting autonomic and hemodynamic effects of insulin in healthy elderly versus young subjects
26. Aging and endothelial function in normotensive subjects and patients with essential hypertension
27. Impaired nitric oxide-mediated vasodilatation and total body nitric oxide production healthy old age
28. Differential effects of hyperinsulinemia and carbohydrate metabolism on sympathetic nerve activity and muscle blood flow in humans