Structural basis for preferential binding of H-NS to curved DNA

Biochimie

Volumn 83, Issue 2, 2001, Pages 231-234

  Dame, R T ^a   Wyman, C ^b   Goosen, N ^a  

^a LEIDEN UNIVERSITY   (Netherlands)

^b ERASMUS MEDICAL CENTER   (Netherlands)

Author keywords

Bacterial chromatin; DNA condensation; DNA curvature; H ns; Scanning force microscopy

Indexed keywords

BACTERIAL DNA; BACTERIAL PROTEIN; CURVED DNA;

ARTICLE; ATOMIC FORCE MICROSCOPY; BACTERIAL CHROMOSOME; BACTERIAL GENE; BINDING SITE; CHROMATIN; CHROMOSOME CONDENSATION; DNA BINDING; DNA PROTEIN COMPLEX; ESCHERICHIA COLI; MODEL; MOLECULAR RECOGNITION; NONHUMAN; PROMOTER REGION; SCANNING FORCE MICROSCOPY; STRUCTURE ANALYSIS; TRANSCRIPTION REGULATION;

BACTERIAL PROTEINS; DNA PRIMERS; DNA, BACTERIAL; DNA-BINDING PROTEINS; ESCHERICHIA COLI; MICROSCOPY, ATOMIC FORCE; NUCLEIC ACID CONFORMATION; POLYMERASE CHAIN REACTION; PROTEIN BINDING; PROTEIN CONFORMATION;

BACTERIA (MICROORGANISMS); ESCHERICHIA COLI;

EID: 0035083490     PISSN: 03009084     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0300-9084(00)01213-X     Document Type: Article

References (26)

1. Histone-like proteins in the purified Escherichia coli deoxyribonucleoprotein
2. Lethal overproduction of the Escherichia coli nucleoid protein H-NS: Ultramicroscopic and molecular autopsy
3. In vivo supercoiling of plasmid and chromosomal DNA in an Escherichia coli hns mutant
4. The oligomeric structure of nucleoid protein H-NS is necessary for recognition of intrinsically curved DNA and for DNA bending
5. H-NS: A modulator of environmentally regulated gene expression
6. Interactions of the nucleoid-associated DNA-binding protein H-NS with the regulatory region of the osmotically controlled proU operon of Escherichia coli
7. Expression of the gene encoding the major bacterial nucleotide protein H-NS is subject to transcriptional auto-repression
8. Thermoregulation of Shigella and Escherichia coli EIEC pathogenecity. A temperature-dependent structural transition of DNA modulates accessibility of virF promoter to transcriptional repressor H-NS
9. Promoter-specific repression of fimB expression by the Escherichia coli nucleoid-associated protein H-NS
10. Evidence for a regulatory function of the histone-like Escherichia coli protein H-NS in ribosomal RNA synthesis
11. Cryptic operon for beta-glucoside metabolism in Escherichia coli K12: Genetic evidence for a regulatory protein
12. Integration host factor alleviates the H-NS-mediated repression of the early promoter of bacteriophage Mu
13. Protein H1: A role for chromatin structure in the regulation of bacterial gene expression and virulence?
14. Conformational changes of the upstream DNA mediated by H-NS and FIS regulate E. Coli rrnB P1 promoter activity
15. The chromatin-associated protein H-NS interacts with curved DNA to influence DNA topology and gene expression
16. Function of the Escherichia coli nucleoid protein, H-NS: Molecular analysis of a subset of proteins whose expression is enhanced in a hns deletion mutant
17. Oligomerization of the chromatin-structuring protein H-NS
18. Modulated expression of promoters containing upstream curved DNA sequences by the Escherichia coli nucleoid protein H-NS
19. DNA binding is not sufficient for H-NS-mediated repression of proU expression
20. Escherichia coli protein analogs StpA and H-NS: Regulatory loops, similar and disparate effects on nucleic acid dynamics
21. H-NS mediated compaction of DNA visualised by atomic force microscopy
22. Polymer chain statistics and conformational analysis of DNA molecules with bends or sections of different flexibility
23. The Escherichia coli nucleoid protein H-NS functions directly as a transcriptional repressor
24. The bacterial DNA-binding protein H-NS represses ribosomal RNA transcription by trapping RNA polymerase in the initiation complex
25. DNA bending and wrapping around RNA polymerase: A 'revolutionary' model describing transcriptional mechanisms
26. CURVATURE: Software for the analysis of curved DNA