Oligomerization of the chromatin-structuring protein H-NS

Molecular Microbiology

Volumn 36, Issue 4, 2000, Pages 962-972

  Smyth, Clare P ^a   Lundbäck, Thomas ^a   Renzoni, Debora ^a   Siligardi, Giullano ^b   Beavil, Rebecca ^b   Layton, Meredith ^c   Sidebotham, Julie M ^d   Hinton, Jay C D ^d   Driscoll, Paul C ^a,c   Higgins, Christopher F ^d,e   Ladbury, John E ^a  

^a UNIVERSITY COLLEGE LONDON   (United Kingdom)

^b KING'S COLLEGE LONDON   (United Kingdom)

^c LUDWIG INSTITUTE FOR CANCER RESEARCH   (United Kingdom)

^d UNIVERSITY OF OXFORD   (United Kingdom)

^e HAMMERSMITH HOSPITAL   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

BACTERIAL PROTEIN; DNA BINDING PROTEIN; POLYPEPTIDE;

ALPHA HELIX; AMINO ACID SEQUENCE; AMINO TERMINAL SEQUENCE; ARTICLE; CARBOXY TERMINAL SEQUENCE; CHROMATIN; DNA BINDING; GENE EXPRESSION REGULATION; NONHUMAN; OLIGOMERIZATION; PRIORITY JOURNAL; PROTEIN TERTIARY STRUCTURE; SALMONELLA TYPHIMURIUM; STRUCTURE ACTIVITY RELATION;

AMINO ACID SEQUENCE; BACTERIAL PROTEINS; DNA-BINDING PROTEINS; MOLECULAR SEQUENCE DATA; NUCLEAR MAGNETIC RESONANCE, BIOMOLECULAR; OLIGOPEPTIDES; PROTEIN STRUCTURE, SECONDARY; SALMONELLA TYPHIMURIUM;

BACTERIA (MICROORGANISMS); NEGIBACTERIA; SALMONELLA TYPHIMURIUM; TYPHIMURIUM;

EID: 0034072251     PISSN: 0950382X     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1365-2958.2000.01917.x     Document Type: Article

References (32)

1. Boucher, W. (1996) AZARA v2.0. Cambridge, UK: Department of Biochemistry, University of Cambridge.
2. Bracco, L., Kotlarz, D., Kolb, A., Diekmann, S., and Buc, H. (1989) Synthetic curved DNA-sequences can act as transcriptional activators in Escherichia coli. EMBO J 8: 4289-4296.
3. Cusick, M.E., and Belfort, M. (1998) Domain structure and RNA annealing activity of the Escherichia coli regulatory protein StpA. Mol Microbiol 28: 847-857.
4. Delaglio, F., Grzesisek, S., Vuister, G.W., Zhu, G., Pfeifer, J., and Bax, A. (1995) NMR-Pipe - A multidimensional spectral processing system based on UNIX pipes. J Biomol NMR 6: 277-293.
5. Dorman, C.J., Hinton, J.C.D., and Free, A. (1999) Domain organization and oiigomerization among H-NS-like nucleoid-associated proteins in bacteria. Trends Microbiol 7: 124-128.
6. Drlica, K., and Rouviere-Yaniv, J. (1987) Histone-like proteins of bacteria. Microb Rev 51: 301-319.
7. Falconi, M., Gualtieri, M.T., LaTeana, A., Losso, M.A., and Pon, C.L. (1988) Proteins from the prokaryotic nucleoid - Primary and quaternary structure of the 15 kDa Escherichia coli DNA-binding protein, H-NS. Mol Microbiol 2: 323-329.
8. Hennessey, J., and Johnson, W.C. (1981) Information content in the circular dichroism of proteins. Biochemistry 20: 1085-1094.
9. Higgins, C.F., Dorman, C.J., Stirling, D.A., Waddell, L., Booth, I.R., May, G., et al. (1988) A physiological role for DNA supercoiling in the osmotic regulation of gene expression in S. typhimurium and E. coli. Cell 52: 569-584.
10. Higgins, C.F., Hinton, J.C.D., Hulton, C.S.J., Owen-Hughes, T., Pavitt, G.D., and Seirafi, A. (1990) Protein H1: a role for chromatin structure in the regulation of bacterial gene expression and virulence? Mol Microbiol 4: 2007-2012.
11. Hulton, C.S.J., Seirafi, A., Hinton, J.C.D., Sidebotham, J.M., Waddell, L., Pavitt, G.D., et al. (1990) Histone-like protein H1 (H-NS), DNA supercoiling and gene expression in bacteria. Cell 63: 631-642.
12. Jordi, B.J.A.M., Fielder, A.E., Burns, C.M., Hinton, J.C.D., Dover, N., Ussery, D.W., et al. (1997) DNA binding is not sufficient for H-NS mediated repression of proU expression. J Biol Chem 272: 12083-12090.
13. Laurent-Winter, C., Ngo, S., Danchin, A., and Bertin, P. (1997) Role of Escherichia coli histone-like nucleoid structuring protein in bacterial metabolsim and stress response. Identification of targets by two-dimensional electrophoresis. Eur J Biochem 244: 767-773.
14. Lupas, A. (1996) Coiled-coils: New structures and new functions. Trends Biochem Sci 21: 375-382.
15. Macura, S., Huang, Y., Suter, D., and Ernst, R.R. (1981) Two-dimensional chemical exchange and cross-relaxation spectroscopy of coupled nuclear spins. J Magn Reson 43: 259-281.
16. Maniatis, T., Fritsch, E.F., and Sambrook, J. (1982) Molecular Cloning: a Laboratory Manual. Cold Spring Harbor, NY: Cold Spring Harbor Laboratory Press.
17. Owen-Hughes, T.A., Pavitt, G.D., Santos, D.S., Sidebotham, J.M., Hulton, C.S.J., Hinton, J.C.D., et al. (1992) The chromatin-associated protein H-NS interacts with curved DNA to influence DNA topology and gene expression. Cell 71: 255-265.
18. Pettijohn, D.E. (1988) Histone-like proteins and bacterial chromosome structure. J Biol Chem 263: 12793-12796.
19. Rosenberg, H.A., Lade, B.N., Chui, D.S., Lin, S.W., Dunn, J.J., and Studier, F.W. (1987) Vectors for selective expression of cloned DNAs by T7 RNA polymerase. Gene 56: 125-135.
20. Shindo, H., Iwaki, T., Ieda, R., Kurumizaka, H., Ueguchi, C., Mizuno, T., et al. (1995) Solution structure of the DNA-binding domain of a nucleoid-associated protein, H-NS, from Escherichia coli. FEBS Microbiol Lett 360: 125-131.
21. Spurio, R., Falconi, M., Brandi, A., Pon, C.L., and Gualerzi, C.O. (1997) The oligomeric structure of nucleoid protein H-NS is necessary for recognition of intrinsically curved DNA and for DNA bending. EMBO J 16: 1795-1805.
22. Studier, F.W., and Moffat, B.A. (1986) Use of bacteriophage T7 RNA polymerase to direct selective high level expression of cloned genes. J Mol Biol 189: 113-130.
23. Tabor, S., and Richardson, C.C. (1985) A Bacteriophage T7 RNA polymerase promoter system for controlled exclusive expression of specific genes. Proc Natl Acad Sci USA 82: 1074-1078.
24. Tippner, D., and Wagner, R. (1995) Fluorescence analysis of the Escherichia coli transcription regulator, H-NS reveals two distinguishable complexes dependent on binding to specific or nonspecific DNA sites. J Biol Chem 38: 22243-22247.
25. Tupper, A.E., Owen-Hughes, T.A., Ussery, D.W., Santos, D.S., Ferguson, D.J.P., Sidebotham, J.M., et al. (1994) The chromatin-associated protein H-NS alters DNA topology in vitro. EMBO J 13: 258-268.
26. Ueguchi, C., Suzuki, T., Yoshida, T., Tanaka, K., and Mizuno, T. (1996) Systematic mutational analysis revealing the functional domain organization of Escherichia coli nucleoid protein H-NS. J Mol Biol 263: 149-162.
27. Ueguchi, C., Seto, C., Suzuki, T., and Mizuno, T. (1997) Clarification of the dimerization domain and its functional significance for the Escherichia coli nucleoid protein H-NS. J Mol Biol 274: 145-151.
28. Ussery, D.W., Hinton, J.C.D., Jordi, B.J.A.M., Granum, P.E., Seirafi, A., Stephen, R.J., et al. (1994) The chromatin-associated protein H-NS. Biochimie 76: 968-980.
29. Williams, R.M., and Rimsky, S. (1997) Molecular aspects of the E. coli nucleoid protein H-NS: a central controller of gene regulatory networks. FEMS Microbiol Lett 156: 175-185.
30. Williams, R.M., Rimsky, S., and Buc, H. (1996) Probing the structure, function, and interactions of the Escherichia coli H-NS and StpA proteins by using dominant negative derivatives. J Bacteriol 178: 4335-4343.
31. Yamada, H., Muramatsu, S., and Mizuno, T. (1990) An Escherichia coli protein that preferentially binds to sharply curved DNA. J Biochem (Tokyo) 108: 420-425.
32. Zeng, X., Herdon, A.M., and Hu, J.C. (1997) Buried asparagines determine the dimerization specificities of leucine zipper mutants. Proc Natl Acad Sci USA 94: 3673-3678.