Chromosomal aberrations in human hepatocellular carcinomas associated with hepatitis C virus infection detected by comparative genomic hybridization

British Journal of Cancer

Volumn 80, Issue 12, 1999, Pages 2034-2039

  Sakakura, C ^a   Hagiwara, A ^a   Taniguchi, H ^a   Yamaguchi, T ^a   Yamagishi, H ^a   Takahashi, T ^a   Koyama, K ^b   Nakamura, Y ^b   Abe, T ^a   Inazawa, J ^a,b,c  

^a KYOTO PREFECTURAL UNIVERSITY OF MEDICINE   (Japan)

^b THE UNIVERSITY OF TOKYO   (Japan)

^c TOKYO MEDICAL AND DENTAL UNIVERSITY   (Japan)

Author keywords

CGH; Chromosomal aberrations; Hepatocellular carcinomas

Indexed keywords

ARTICLE; CHROMOSOME 11Q; CHROMOSOME 13Q; CHROMOSOME 14Q; CHROMOSOME 16Q; CHROMOSOME 17P; CHROMOSOME 17Q; CHROMOSOME 1P; CHROMOSOME 4Q; CHROMOSOME 5Q; CHROMOSOME 6Q; CHROMOSOME 7Q; CHROMOSOME 8P; CHROMOSOME ABERRATION; CHROMOSOME LOSS; CLINICAL ARTICLE; CONTROLLED STUDY; DNA HYBRIDIZATION; DNA SEQUENCE; GENE AMPLIFICATION; HEPATITIS B; HEPATITIS C; HEPATITIS C VIRUS; HUMAN; HUMAN CELL; LIVER CARCINOGENESIS; LIVER CELL CARCINOMA; PRIORITY JOURNAL;

CARCINOMA, HEPATOCELLULAR; CHROMOSOME ABERRATIONS; CHROMOSOME DELETION; CHROMOSOME MAPPING; FEMALE; HEPATITIS C; HUMANS; KARYOTYPING; LIVER NEOPLASMS; LOSS OF HETEROZYGOSITY; MALE; NEOPLASM STAGING; NUCLEIC ACID HYBRIDIZATION; REFERENCE VALUES;

EID: 0032779723     PISSN: 00070920     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.bjc.6690638     Document Type: Article

References (45)

1. Ariyama Y, Fukuda Y, Okuno Y, Seto M, Date K, Abe T, Nakamura Y and Inazawa J (1998) Amplification on double-minute chromosomes and partial-tandem duplication of the MLL gene in leukemic cells of a patient with acute myelogenous leukemia. Genes Chromosomes Cancer 23: 267-272
2. Borg A, Zhang QX, Olsson H and Wenngren E (1992) Chromosome 1 alterations in breast cancer: allelic loss on 1p and 1q is related to lymphogenic metastases and poor prognosis. Genes Chromosomes Cancer 5: 311-320
3. Buctow KH, Murray JC, Israel JL, London WT, Smith M, Kew M, Blanquet V, Brechot C, Redeker A and Govindarajah S (1989) Loss of heterozygosity suggests tumor suppressor gene responsible for primary hepatocellular carcinoma. Proc Natl Acad Sci USA 86: 8852-8856
4. Cano J, Oliveros O and Yunis E (1994) Phenotype of variants malignancy, additional copies of 6p in retinoblastoma. Cancer Genes Cytogenet 76: 112-115
5. Di Biscegli AM (1997) Hepatitis C and hepatocellular carcinoma. Hepatology 26: 34S-38S
6. Emi M, Fujiwara Y, Ohata H, Tsuda H, Hirohashi S, Koike M, Miyaki M, Monden M and Nakamura Y (1993) Allelic loss at chromosome band 8p21.3-p22 is associated with progression of hepatocellular carcinoma. Genes Chromosomes Cancer 7: 152-157
7. Fong TL, Shindo M, Feinstone SM, Hoofnagle JH and Di Bisceglie AM (1991) Detection of replicative intermediates of hepatitis C viral RNA in liver and serum of patients with chronic hepatitis C. J Clin Invest 88: 1058-1060
8. Forus A, Weghuis DO, Smeets D, Fodstad O, Myklebost O and Geurts Van Kessel A (1995) Comparative genomic hybridization analysis of human sarcomas: II. Identification of novel amplicons at 6p and 17p in osteosarcomas. Genes Chromosomes Cancer 14: 15-21
9. Fourel G (1994) Genetic and epigenetic alterations of gene expression in the course of hepatocarcinogenesis. In: Liver Gene Expression, Tronche F and Moshe Y (eds), pp. 298-343. R.G. Landes: Austin, TX
10. Fujimori M, Tokino T, Hino O, Kitagawa T, Imamura T, Okamoto E, Mitsunobu M, Ishikawa T, Nakagawa H, Hayada H, Yagura M, Matsubara K and Nakamura Y (1991) Allotype study of primary hepatocellular carcinoma. Cancer Res 51: 89-93
11. Fugimoto Y, Hampton LL, Wirth PJ, Wang NJ, Xie JP and Thorgeirsson SS (1994) Alteration of tumor suppressor genes and allelic losses in human hepatocellular carcinomas in China. Cancer Res 54: 281-285
12. Fujiwara Y, Ohata H, Emi M, Okui K, Koyama K, Tsuchiya E, Nakajima T, Monden M, Mori T, Kurimasa A, Oshimura M and Nakamura Y (1994) A 3-Mb physical map of the chromosome region 8p21.3 p22, including a 600-kb region commonly deleted in human hepatocellular carcinoma, colorectal cancer, and non-small cell lung cancer. Genes Chromosomes Cancer 10: 7-14
13. Kaghad M, Bonnet H, Yang A, Creancier L, Biscan JC, Valent A, Minty A, Chalon P, Lelias JM, Dumont X, Ferrara P, McKeon, F and Capul D (1997) Monoallelically expressed gene related to p53 at 1p36, a region frequently deleted in neuroblastoma and other human cancers. Cell 90: 809-819
14. Kallioniemi A, Kallioniemi OP, Sudar D, Rutovitz D, Gray JW, Waldman F and Pinkel D (1992) Comparative genomic hybridization for molecular cytogenetic analysis of solid tumors. Science 258: 818-820
15. Kallioniemi A, Kallioniemi O-P, Piper J, Tanner M, Stokke T, Chen L, Smith HS, Pinkel D, Gray JW and Waldman FM (1994) Detection and mapping of amplified DNA sequences in breast cancer by comparative genomic hybridization. Proc Natl Acad Sci USA 91: 2156-2160
16. Kameda T, Yasui W, Yoshida K, Tsujino T, Nakayama H, Ito M, Ito H and Tahara F, (1990) Expression of ERBB2 in human gastric carcinomas; relationship between p185ERBB2 and the gene amplification. Cancer Res 15: 8002-8009
17. Kasai Y, Takeda S and Takagi H (1996) Pathogenesis of hepatocellular carcinoma: a review from the viewpoint of molecular analysis. Semin Surg Oncol 12: 155-159
18. Knuutila S, Bjorkqvist AM, Autio K, Tarkkanen M, Wolf M, Monni O, Szymanska J, Larramendy ML, Tapper J, Pere H, El-Rifai W, Hemmer S, Wasenius VM, Vidgren V and Zhu Y (1998) DNA copy number amplifications in human neoplasms: review of comparative genomic hybridization studies. Am J Pathol 152: 1107-1123
19. Kruh GD, Perego R, Miki T and Aaronson SA (1990) The complete coding sequence of arg defines the Abelson subfamily of cytoplasmic tyrosine kinases. Proc Natl Acad Sci USA 87: 5802-5806
20. Kuroki T, Fujiwara Y, Tsuchiya E, Nakamori S, Imaoka S, Kanematsu F and Nakamura Y (1995) Accumulation of genetic changes during development of and progression of hepatocellular carcinoma: Loss of heterozygosity on chromosome arm 1p occurs at early stage of hepatocarcinogenesis. Genes Chromosomes Cancer 13: 163-167
21. Lowichik A, Schneider NR, Tonk V, Ansari MQ and Timmons CF (1996) Report of a complex karyotype in recurrent metastatic fibrolamellar hepatocellular carcinoma and a review of hepatocellular carcinoma cytogenetics. Cancer Genet Cytogenet 88: 170-174
22. Marchio A, Meddeb M, Pineau P, Danglot G, Tiollais P, Bernheim A and Dejean A (1997) Recurrent chromosomal abnormalities in hepatocellular carcinoma delected by comparative genomic hybridization. Genes Chromosomes Cancer 18: 59-65
23. Moroy T, Marchio A, Euemble J, Trepo C, Tiollais P and Buendia MA(1986) Rearrangement and enhanced expression of c mye in hepatocellular carcinoma of hepatitis virus infected woodchucks. Nature 324: 276-279
24. Nagai H, Piecau P, Tiollais P, Buendia MA and Dejean A (1997) Comprehensive allelotyping of human hepatocellular carcinoma. Oncogene 14: 2927-2933
25. Nalpas B, Driss F, Pol S, Hamelin B, Housset C, Brechot C and Berthelot P (1991) Association between HCV and HBV infection in hepatocellular carcinoma and alcoholic liver disease. J Hepatol 12: 70-74
26. Nishida N, Fukuda Y, Ishizaki K and Nakao K (1997) Alteration of cell cycle related genes in hepatocarcinogenesis. Histol Histopathol 12: 1019-1025
27. Oda T, Tsuda H, Scarpa A, Sakamoto M and Hirahashi S (1992) P53 gene mutation spectrum in hepatocellular carcinoma. Cancer Res 52: 6358-6364
28. Rogler CF, and Chisari FV (1992) Cellular and molecular mechanisms of hepatocarcinogenesis. Semin Liver Dis 12: 265-278
29. Sakakura C, Mori T, Sakabe T, Ariyama Y, Shinomiya T, Date K, Hagiwara A, Yamaguchi T, Takahashi T, Nakamura Y, Abe T and Inazawa J (1999) Gains, losses, and amplifications of genomic materials in primary gastric cancers analyzed by comparative genomic hybridization. Genes Chromosomes Cancer 24: 299-305
30. Schaapveld RQ, Van Den Maagdenberg AM, Schepens JT, Weghuis DO, Geurts Van Kessel A, Wieringa B and Hendriks WJ (1995) The mouse gene Ptprf encoding the leukocyte common antigen-related molecule LAR: cloning, characterization, and chromosomal localization. Genomics 27; 124-130
31. Simon D, Knowles BB and Weith A (1991) Abnormalities of chromosome I and loss of heterozygosity of 1p in primary hepatomas. Oncogene 6: 765-770
32. Simon D, and Carr BI (1995) Integration of hepatitis B virus and alteration of the 1p36 region found in cancerous tissue of primary hepatocellular carcinoma with viral replication evidenced only in noncancerous, cirrhotic tissue. Hepathology 22: 1393-1398
33. Tabor E (1994) Tumor suppressor genes, growth factor genes, and oncogenes in hepatitis B virus-associated hepatocellular carcinoma. J Med Virol 42; 357-365
34. Tahara E (1995) Molecular biology of gastric cancer. Wolrd J Surg 19: 484-488
35. Takano S, Yokosuka O, Imazcki F, Tagawa M and Omata M (1995) Incidence of hepatocellular carcinoma in chronic hepatitis B and C: a prospective study of 251 patients. Hepathology 21: 650-655
36. Tanaka K, Hirohata T, Koga S, Sugimachi K, Kanematsu T, Ohryohji F, Nawata H, Ishibashi H, Maeda Y, Kiyokawa M, Tokunaga K, Inta Y, Takeshita S, Arase Y and Nishino N (1991) Hepatitis C and hepatitis B in the etiology of hepatocellular carcinoma in the Japanese population. Cancer Res 51: 2842-2847
37. The Liver Cancer Study Group of Japan (1994) Predictive factors for long term prognosis after partial hepatectomy for patients with hepatocellular carcinoma in Japan. Cancer 74: 2772-2780
38. Tokino T, Fukushige S, Nakamura T, Nagaya T, Murotsu T, Shiga K, Aoki N and Matsubara K (1987) Chromosomal translocation and inverted duplication associated with integrated hepatitis B virus DNA in hepatocellular carcinomas. J Virol 61: 3848-3854
39. Tsuda H, Zhang W, Shimosato Y, Yokota J, Terada M, Sugmura T, Miyamura T and Hirohashi S (1990) Allele loss on chromosome 16 associated with progression of human hepatocellular carcinoma. Proc Natl Acad Sci USA 87: 6791-6794
40. Van Rensburg SJ, Cook Mozafarri P, Van Schlkwyk DJ, Van Der Watt JJ, Vincent TJ and Purchase IF (1985) Hepatocellular carcinoma and dietary aflatoxin in Mozambique and Transkei. Br J Cancer 51: 713-726
41. Wann J, Chenivesse X, Henglein B and Brechot C (1990) Hepatitis B virus integration in a cyclin A gene in a hepatocellular carcinoma. Nature 343: 555-557
42. Whelan SL, Parkin DM and Masuyer E (eds) (1993) Trends in Cancer Incidence and Mortality. IARC Scientific Publ., No. 102. IARC: Lyon
43. Yeh SH, Chen PJ, Chen HL, Lai MY, Wang CC and Chen DS (1994) Frequent genetic alterations at the diastal region of chromosome 1p in human hepatocellular carcinomas. Cancer Res 54: 4188-4192
44. Yeh SH, Chen PJ, Lai MY and Chen DS (1996) Allelic loss on chromosome 4q and 16q in hepatocellular carcinoma: association with elevated α-fetoprotein production. Gastroenterology 110: 184-192
45. Zhang W, Hirohashi S, Tsuda H, Shimosato Y, Yokota J, Terada M and Sugimura T (1990) Frequent loss of heterozygosity of chromosomes 16 and 4 in human hepatocellular carcinoma. Jpn J Cancer Res 81: 108-111