The cardiac endothelium: Cardioactive mediators

Progress in Cardiovascular Diseases

Volumn 39, Issue 3, 1996, Pages 263-284

  Shah, A M ^a   Grocott Mason, R M ^a   Pepper, C B ^a   Mebazaa, A ^a   Henderson, A H ^a   Lewis, M J ^a   Paulus, W J ^a  

^a CARDIFF UNIVERSITY   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

ADENINE; ADENOSINE TRIPHOSPHATE; ENDOTHELIN; INOTROPIC AGENT; NITRIC OXIDE; PROSTANOID; PURINE;

ARTICLE; CALCIUM TRANSPORT; CORONARY ARTERY BLOOD FLOW; DIASTOLE; ENDOTHELIUM; HEART CONTRACTION; HEART INFARCTION; HEART MUSCLE CONTRACTILITY; HEART MUSCLE ISCHEMIA; HEART MUSCLE RELAXATION; HEART PERFORMANCE; HEART RATE; HUMAN; INOTROPISM; MEDIATOR RELEASE; NONHUMAN; STARLING LAW;

EID: 0030472216     PISSN: 00330620     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0033-0620(96)80005-3     Document Type: Article

References (140)

1. Henderson AH Endothelium in control Br Heart J 65 1991 116 125
2. Brutsaert DL Andries LJ The endocardial endothelium Am J Physiol 263 1992 H985 H1002
3. Shah AM Lewis MJ Modulation of myocardial contraction by endocardial and coronary vascular endothelium Trends Cardiovasc Med 3 1993 98 103
4. Brutsaert DL Meulemans AL Sipido KR Sys SU Effects of damaging the endocardial surface on the mechanical performance of isolated cardiac muscle Circ Res 62 1988 358 366
5. Gillebert TC De Hert SG Andries LJ Intracavitary ultrasound impairs left ventricular performance: Presumed role of endocardial endothelium Am J Physiol 263 1992 H857 H865
6. Fort S Lewis MJ Shah AM The role of endocardial endothelium in the modulation of myocardial contraction in the isolated whole heart Cardioscience 4 1993 217 223
7. 1-adrenoceptor agonist in mammalian heart J Mol Cell Cardiol 22 1990 667 685
8. Shah AM Meulemans AL Brutsaert DL Myocardial inotropic responses to aggregating platelets and modulation by the endocardium Circulation 79 1989 1315 1323
9. Shah AM Andries LJ Meulemans AL Brutsaert DL Endocardium modulates myocardial inotropic response to 5-hydroxytryptamine Am J Physiol 257 1989 H1790 H1797
10. Li K Stewart DJ Rouleau JL Myocardial contractile actions of endothelin-1 in rat and rabbit papillary muscles Circ Res 69 1991 301 312
11. Paulus WJ Vantrimpont PJ Shah AM Acute effects of nitric oxide on left ventricular relaxation and diastolic distensibility in man Circulation 89 1994 2070 2078
12. Paulus WJ Vantrimpont PJ Shah AM Paracrine coronary endothelial control of left ventricular function in humans Circulation 92 1995 2119 2126
13. Shah AM Modulation of myocardial contractile function by endothelium Haunso S Kjeldsen K Proceedings of the International Society for Heart Research European Section Meeting 1994 Monduzzi Editore Bologna 53 60
14. Rüegg JC Towards a molecular understanding of contractility Cardioscience 1 1990 163 167
15. Furchgott RF Zawadski JV The obligatory role of endothelial cells in the relaxation of arterial smooth muscle by acetylcholine Nature 288 1980 373 376
16. Moncada S Palmer RMJ Higgs HA Nitric oxide: Physiology, pathophysiology, and pharmacology Pharmacol Rev 43 1991 109 142
17. Nathan C Nitric oxide as a secretory product of mammalian cells FASEB J 6 1992 3051 3064
18. Stamler JS Singel DJ Loscalzo J Biochemistry of nitric oxide and its redox-activated forms Science 258 1993 1898 1902
19. Smith JA Shah AM Lewis MJ Factors released from the endocardium of the ferret and pig modulate myocardial contraction J Physiol 439 1991 1 14
20. Shah AM Lewis MJ Henderson AH Effects of 8-bromo-cyclic GMP on contraction and on inotropic response of ferret cardiac muscle J Mol Cell Cardiol 23 1990 55 64
21. Grocott-Mason R Fort S Lewis MJ Shah AM Myocardial relaxant effect of exogenous nitric oxide in the isolated ejecting heart Am J Physiol 266 1994 H1699 H1705
22. Grocott-Mason RM Anning PB Evans H Modulation of left ventricular relaxation in isolated ejecting heart by endogenous nitric oxide Am J Physiol 267 1994 H1804 H1813
23. Shah AM Spurgeon H Sollott SJ 8-bromo cyclic GMP reduces the myofilament response to calcium in intact cardiac myocytes Circ Res 74 1994 970 978
24. Pfitzer G Rüegg JC Flockerzi V Hofmann F cGMP-dependent protein kinase decreases calcium sensitivity of skinned cardiac fibers FEBS Lett 149 1982 171 175
25. (abstr) Kojda G Kottenberg K Nix P Opposite responses of rat cardiac myocytes to different nitrovasodilators Circulation 90 1994 I 592
26. Brady AJB Warren JB Poole-Wilson PA Nitric oxide attenuates cardiac myocyte contraction Am J Physiol 265 1993 H176 H182
27. Lamontagne D Pohl U Busse R Mechanical deformation of vessel wall and shear stress determine the basal release of endothelium-derived relaxing factor in the intact rabbit coronary vascular bed Circ Res 70 1992 123 130
28. Hutcheson IR Griffith TM Release of endothelium-derived relaxing factor is modulated both by frequency and amplitude of pulsatile flow Am J Physiol 261 1991 H257 H262
29. Balligand JL Kelly RA Marsden PA Control of cardiac muscle function by an endogenous nitric oxide signaling system Proc Natl Acad Sci USA 90 1993 347 351
30. Wahler GM Dollinger S Nitric oxide donor SIN-1 inhibits mammalian cardiac calcium current through cGMP-dependent protein kinase Am J Physiol 268 1995 C45 C54
31. 2+ current J Biol Chem 268 1994 26286 26295
32. Roberts AB Vodovotz Y Roche NS Role of nitric oxide in antagonistic effects of transforming growth factor-β and interleukin-1β on the beating rate of cultured cardiac myocytes Mol Endocrinol 6 1992 1921 1930
33. Han X Shimoni Y Giles WR An obligatory role for nitric oxide in autonomic control of mammalian heart rate J Physiol 476.2 1994 309 314
34. Lincoln TM Cornwell TL Intracellular cyclic GMP receptor proteins FASEB J 7 1993 328 338
35. ++-independent nitric oxide synthase in the myocardium Br J Pharmacol 105 1992 575 580
36. Brady AJB Poole-Wilson PA Harding SE Warren JB Nitric oxide within cardiac myocytes reduces their contractility in endotoxaemia Am J Physiol 263 1992 H1963 H1966
37. Evans HG Lewis MJ Shah AM Interleukin-1β modulates myocardial contraction via dexamethasone-sensitive production of nitric oxide Cardiovasc Res 27 1993 1486 1490
38. Balligand JL Ungureanu D Kelly RA Abnormal contractile function due to induction of nitric oxide synthesis in rat cardiac myocytes follows exposure to activated macrophage-conditioned medium J Clin Invest 91 1993 2314 2319
39. i and cell contraction in cultured chick ventricular myocytes Circ Res 75 1994 285 295
40. Lancaster JR Langrehr JM Bergonia HA EPR detection of heme and nonheme iron-containing protein nitrosylation by nitric oxide during rejection of rat heart allograft J Biol Chem 267 1992 10994 10998
41. Yang X Chowdhury N Cai B Induction of myocardial nitric oxide synthase by cardiac allograft rejection J Clin Invest 94 1994 714 721
42. Tsujino M Hirata Y Imai T Induction of nitric oxide synthase gene by interleukin-1β in cultured rat cardiocytes Circulation 90 1994 375 383
43. Dudek RR Wildhirt S Pinto V Dexamethasone inhibits the expression of an inducible nitric oxide synthase in infarcted rabbit myocardium Biochem Biophys Res Comm 202 1994 1120 1126
44. De Belder AJ Radomski MW Why HJF Nitric oxide synthase in human myocardium Lancet 341 1993 84 85
45. Finkel MS Oddis CV Jacob TD Negative inotropic effects of cytokines on the heart mediated by nitric oxide Science 257 1992 387 389
46. Shah AM Silverman HS Griffith EJ Cyclic GMP prevents delayed relaxation at reoxygenation following brief hypoxia in isolated cardiac myocytes Am J Physiol 268 1995 H2396 H2404
47. Hasebe N Shen YT Vatner SF Inhibition of endothelium-derived relaxing factor enhances myocardial stunning in conscious dogs Circulation 88 1993 2862 2871
48. Schluter KD Weber M Schraven E Piper HM NO donor SIN-1 protects against reoxygenation-induced cardiomyocyte injury by a dual action Am J Physiol 267 1994 H1461 H1466
49. Lindpaintner K Ganten D The cardiac reninangiotensin system. An appraisal of present experimental and clinical evidence Circ Res 68 1991 905 921
50. Paul M Bachmann J Ganten D The tissue reninangiotensin systems in cardiovascular disease Trends Cardiovasc Med 2 1992 94 99
51. Busse R Lamontagne D Endothelium-derived bradykinin is responsible for the increase in calcium produced by angiotensin-converting enzyme in human endothelial cells Naunyn-Schmiedberg's Arch Pharmacol 344 1991 126 129
52. Baumgarten C Linz W Kunkel G Increases bradykinin outflow from isolated hearts of rat Br J Pharmacol 108 1993 293 295
53. Hecker M Porsti I Bara A Busse R Potentiation by ACE inhibitors of the dilator response to bradykinin in the coronary microcirculation: Interaction at the receptor level Br J Pharmacol 111 1994 238 244
54. Lang D Shah AM Lewis MJ Angiotensin converting enzyme (ACE) activity: aortic and endocardial endothelium compared Endothelium 4 1996 51 61
55. Katwa LC Ratajska A Cleutjens JPM Angiotensin converting enzyme and kininase-II-like activities in cultured valvular interstitial cells of the rat heart Cardiovasc Res 29 1995 57 64
56. Cambien F Poirier O Lecerf L Deletion polymorphism in the gene for angiotensin-converting enzyme is a potent risk factor for myocardial infarction Nature 359 1992 641 644
57. Swedburg K Held P Kjekshus J on behalf of the CONSENSUS II study group: Effects of early administration of enalapril on mortality in patients with acute myocardial infarction. Results of the Cooperative North Scandinavian Enalapril Survival Study II (CONSENSUS II) N Engl J Med 327 1992 678 684
58. Pfeffer M Braunwald E Moye L on behalf of the SAVE Investigators: Effect of captopril on mortality and morbidity in patients with left ventricular dysfunction after myocardial infarction N Engl J Med 327 1992 669 677
59. The SOLVD Investigators Effect of enalapril on mortality and the development of heart failure in asymptomatic patients with reduced left ventricular ejection fractions N Eng J Med 327 1992 685 691
60. Pelc L Gross G Warltier D Mechanism of coronary vasodilation produced by bradykinin Circulation 83 1991 2048 2056
61. Yang S Cheek DJ Westfall DP Buxton ILO Purinergic axis in cardiac blood vessels. Agonist-mediated release of ATP from cardiac endothelial cells Circ Res 74 1994 401 407
62. Mombouli J Illiano S Nagao T Potentiation of endothelium-dependent relaxations to bradykinin by angiotensin I converting enzyme inhibitors in canine coronary artery involves both endothelium-derived relaxing and hyperpolarizing factors Circ Res 71 1992 137 144
63. Fort S Lewis MJ A factor released from coronary vascular endothelium inhibits myocardial contractile performance Am J Physiol 264 1993 H830 H836
64. 2-bradykinin receptor antagonist HOE140 abolishes the antihypertrophic effect of ramipril Br J Pharmacol 105 1992 771 772
65. Parratt JR Cardioprotection by angiotensin converting enzyme inhibitors—the experimental evidence Cardiovasc Res 28 1994 183 189
66. Pahor M Gambassi G Carbonin P Antiarrhythmic effects of ACE inhibitors: a matter of faith or reality? Cardiovasc Res 28 1994 173 182
67. Anning PB Grocott-Mason RM Lewis MJ Shah AM Enhancement of left ventricular relaxation in the isolated heart by an angiotensin converting enzyme inhibitor Circulation 92 1995 2660 2665
68. 1 receptor subtype Circ Res 73 1993 413 423
69. Meulemans AL Andries LJ Brutsaert DL Does endocardial endothelium mediate positive inotropic response to angiotensin I and angiotensin II? Circ Res 66 1990 1591 1601
70. Schunkert H Dzau VJ Tang SS Increased rat cardiac angiotensin converting enzyme activity and mRNA expression in pressure overload left ventricular hypertrophy. Effects on coronary resistance, contractility, and relaxation J Clin Invest 86 1990 1913 1920
71. Holubarsch C Hasenfuss G Schmidt-Schweda S Angiotensin I and II exert inotropic effects in atrial but not ventricular human myocardium Circulation 88 1993 1228 1237
72. Moravec CS Schluchter MD Paranandi L Inotropic effects of angiotensin II on human cardiac muscle in vitro Circulation 82 1990 1973 1984
73. 2+ and pH in isolated beating rabbit hearts and myocytes loaded with the indicator indo-1 J Physiol 480.2 1994 203 215
74. Haber H Powers E Gimple L Intracoronary angiotensin-converting enzyme inhibition improves diastolic function in patients with hypertensive left ventricular hypertrophy Circulation 89 1994 2616 2625
75. Friedrich S Lorell B Rousseau M Intracardiac angiotensin-converting enzyme inhibition improves diastolic function in patients with left ventricular hypertrophy due to aortic stenosis Circulation 90 1994 2761 2771
76. Foult JM Tavolaro O Antony I Nitenberg A Direct myocardial and coronary effects of enalaprilat in patients with dilated cardiomyopathy: Assessment by a bilateral intracoronary infusion technique Circulation 77 1988 337 344
77. Yanagisawa M Kurihara H Kimura S A novel potent vasoconstrictor peptide produced by endothelial cells Nature 332 1988 411 415
78. Rubanyi GM Polokoff MA Endothelins: Molecular biology, biochemistry, pharmacology, physiology, and pathophysiology Pharmacol Rev 46 1994 325 415
79. Suzuki T Kumazaki T Mitsui Y Endothelin 1 is produced and secreted by neonatal rat cardiac myocytes in vitro Biochem Biophys Res Commun 191 1993 823 830
80. Fukuda Y Hirata Y Yoshimi H Endothelin is a potent secretagogue for atrial natriuretic peptide in cultured rat atrial myocytes Biochem Biophys Res Commun 155 1988 167 172
81. Chua BHL Chua CC Diglio CA Siu BB Regulation of endothelin-1 mRNA by angiotensin II in rat heart endothelial cells Biochim Biophys Acta 1178 1993 201 206
82. Ishikawa T Yanagisawa M Kimura S Positive inotropic effect of novel vasoconstrictor peptide endothelin on guinea pig atria Am J Physiol 255 1988 H970 H973
83. Hu JR Von Harsdorf R Lang RE Endothelin has potent inotropic effects in rat atria Eur J Pharmacol 158 1988 275 278
84. Shah AM Lewis MJ Henderson AH Inotropic effects of endothelin in ferret ventricular myocardium Eur J Pharmacol 163 1989 365 367
85. Hirata Y Fukuda Y Yoshimi H Specific receptor for endothelin in cultured rat cardiocytes Biochem Biophys Res Commun 160 1989 1438 1444
86. Moody CJ Dashwood MR Sykes RM Functional and autoradiographic evidence for endothelin 1 receptors on human and rat cardiac myocytes. Comparison with single smooth muscle cells Circ Res 67 1990 764 769
87. Molenaar P O'Reilly G Sharkey A Characterization and localization of endothelin receptor subtypes in the human atrioventricular conducting system and myocardium Circ Res 72 1993 526 538
88. Vigne P Breittmayer JP Frelin C Thapsigargin, a new inotropic agent, antagonizes action of endothelin-1 in rat atrial cells Am J Physiol 263 1992 H1689 H1694
89. Mebazaa A Mayoux E Maeda K Paracrine effects of endocardial endothelial cells on myocyte contraction mediated via endothelin Am J Physiol 265 1993 H1841 H1846
90. Kelly RA Eid H Kramer BK Endothelin enhances the contractile responsiveness of adult rat ventricular myocytes to calcium by a pertussis toxin-sensitive pathway J Clin Invest 86 1990 1164 1171
91. 2+ responsiveness in aequorin-loaded ferret myocardium Circ Res 69 1991 582 589
92. Takanashi M Endoh M Characterization of the positive inotropic effect of endothelin on mammalian ventricular myocardium Am J Physiol 261 1991 H611 H619
93. Hilal-Dandan R Urasawa K Brunton LL Endothelin inhibits adenylate cyclase and stimulates phosphoinositide hydrolysis in adult cardiac myocytes J Biol Chem 267 1992 10620 10624
94. 2+ current by a G protein-dependent mechanism in rabbit cardiac myocytes J Physiol 448 1992 729 747
95. Furukawa T Ito H Nitta J Endothelin-1 enhances calcium entry through T-type calcium channels in cultured neonatal rat ventricular myocytes Circ Res 71 1992 1242 1253
96. + exchanger Circ Res 68 1990 269 279
97. Wang J Flemal K Morgan JP Endothelin-1 enhances cross-bridge function of ferret myocardium: Role of second messengers Am J Physiol 265 1993 H2168 H2174
98. 2+ transient and contractility in ferret myocardium Circ Res 71 1992 631 639
99. (abstr) Shah AM Mebazaa A Lakatta EG Factors released by endothelial cells modulate cardiac diastolic tone Circulation 88 1993 I 86
100. Moravec CS Reynolds EE Stewart RW Bond M Endothelin is a positive inotropic agent in human and rat heart in vitro Biochem Biophys Res Commun 159 1989 14 18
101. Ono K Tsujimoto G Sakomoto A Endothelin-A receptor mediates cardiac inhibition by regulating calcium and potassium currents Nature 370 1994 301 304
102. + current in atrial cells Circ Res 69 1991 250 255
103. James AF Xie LH Fujitani Y Inhibition of the cardiac protein kinase A-dependent chloride conductance by endothelin-1 Nature 370 1994 297 300
104. Wagner OF Christ G Wojta J Polar secretion of endothelin-1 by cultured endothelial cells J Biol Chem 267 1992 16066 16068
105. Siney L Lewis MJ Nitric oxide modulates endothelin release from porcine cultured endocardial endothelium Endothelium 2 1994 169 175
106. Nishida M Springhorn JP Kelly RA Smith TW Cell-cell signaling between adult rat ventricular myocytes and cardiac microvascular endothelial cells in heterotypic primary culture J Clin Invest 91 1993 1934 1941
107. Eid H Kuroski de Bold M Chen JH de Bold AJ Epicardial mesothelial cells synthesize and release endothelin J Cardiovasc Pharmacol 24 1994 715 720
108. McClellan G Weisberg A Rose D Winegrad S Endothelial cell storage and release of endothelin as a cardioregulatory mechanism Circ Res 70 1994 787 803
109. Evans HG Lewis MJ Shah AM Modulation of myocardial relaxation by basal release of endothelin from endocardial endothelium Cardiovasc Res 28 1994 1694 1699
110. (abstr) Prendergast BP Anning PB Lewis MJ Shah AM Endogenous endothelin modulates left ventricular relaxation in the isolated heart Br Heart J 73 1995 46
111. + exchange in mediating effects of endothelin-1 on normal and ischemic/reperfused hearts Circ Res 75 1994 369 378
112. 125I]endothelin-1 binding to rat cardiac membranes J Cardiovasc Pharmacol 15 1990 436 443
113. Hayashida W Donckier J Van Mechelen H Endothelin-1 exacerbates diastolic stunning in conscious dogs Am J Physiol 265 1993 H1688 H1695
114. Yanagisawa M The endothelin system. A new target for therapeutic intervention Circulation 89 1994 1320 1322
115. Shubeita HE McDonough PM Harris AN Endothelin induction of inositol phospholipid hydrolysis, sarcomere assembly, and cardiac gene expression in ventricular myocytes J Biol Chem 265 1990 13809 13817
116. Bogoyevitch MA Glennon PE Sugden PH Endothelin 1, phorbol esters and phenylephrine stimulate MAP kinase activities in ventricular cardiomyocytes FEBS Lett 317 1993 271 275
117. Ito H Hirata Y Adachi S Endothelin-1 is an autocrine/paracrine factor in mechanism of angiotensin II-induced hypertrophy in cultured rat cardiomyocytes J Clin Invest 92 1993 398 403
118. A receptor antagonist blocks cardiac hypertrophy provoked by hemodynamic overload Circulation 89 1994 2198 2203
119. Liang BT Adenosine receptors and cardiovascular function Trends Cardiovasc Med 2 1992 100 108
120. Downey JM Liu GS Thornton JD Adenosine and the anti-infarct effects of preconditioning Cardiovasc Res 27 1993 3 8
121. (suppl) Burnstock G Vascular control by purines with emphasis on the coronary system Eur Heart J 10F 1989 15 21
122. (abstr) (suppl) Anning P Grocott-Mason R Lewis MJ Shah AM Adenylpurines contribute to the myocardial relaxant effects of bradykinin in the intact heart Br Heart J 71 1994 P48
123. Danziger RS Raffaeli S Moreno-Sanchez R Extracellular ATP has a potent effect to enhance cytosolic calcium and contractility in single ventricular myocytes Cell Calcium 9 1988 193 199
124. Scamps F Legssyer A Mayoux E Vassort G The mechanism of positive inotropy induced by adenosine triphosphate in rat heart Circ Res 67 1990 1007 1016
125. Dusting GJ MacDonald PS Prostacyclin and vascular function: implications for hypertension and atherosclerosis Pharmacol Ther 48 1990 323 344
126. 2 J Mol Cell Cardiol 25 1993 245 248
127. Mebazaa A Wetzel R Cherian M Abraham M Comparison between endocardial and great vessel endothelial cells: Morphology, growth and prostaglandin release Am J Physiol 268 1995 H250 H259
128. Mullane KM Fornabiaio D Thromboxane synthetase inhibitors reduce infarct size by a platelet-dependent, aspirin-sensitive mechanism Circ Res 62 1988 668 678
129. Farber NE Pieper GM Thomas JP Gross GJ Beneficial effects of iloprost in the stunned canine myocardium Circ Res 62 1988 204 215
130. Schrör K Hohfeld T Inotropic effects of eicosanoids Basic Res Cardiol 87 1992 2 11
131. Fassina G Tessari F Dorigo P Positive inotropic effect of a stable analogue of PGI2 in isolated guinea pig atria. Mechanism of action Pharmacol Res Commun 15 1983 735 749
132. 2+ exchange in isolated myocardial muscle cells Prostaglandins Leukotr Med 12 1983 305 314
133. Couttenye MM De Clerck NM Herman AG Brutsaert DL Effects of prostacyclin on contractile properties of isolated mammalian cardiac muscle J Cardiovasc Pharmacol 9 1985 971 976
134. Shah AM Mebazaa A Wetzel RC Lakatta EG Novel cardiac myofilament desensitizing factor released by endocardial and vascular endothelial cells Circulation 89 1994 2492 2497
135. Ramaciotti C Sharkey A McClellan G Winegrad S Endothelial cells regulate cardiac contractility Proc Nat Acad Sci 89 1992 4033 4036
136. Ramaciotti C McClellan G Sharkey A Cardiac endothelial cells modulate contractility of rat heart in response to oxygen tension and coronary flow Circ Res 72 1993 1044 1064
137. Pepper CB Lang D Lewis MJ Shah AM Endothelial inhibition of myofilament calcium response in intact cardiac myocytes Am J Physiol 269 1995 H1538 H1544
138. 2+-independent inhibition of actomyosin crossbridge cycling in cardiac myocytes by endothelial cell factors in response to hypoxia (abstr) J Physiol 475 1994
139. Ross J Myocardial perfusion-contraction matching. Implications for coronary heart disease and hibernation Circulation 83 1991 1076 1083
140. Lakatta EG Length modulation of muscle performance. Frank-Starling law of the heart Fozzard HA The heart and cardiovascular system 1992 Raven 1325 1351