Hypertrophie Responses of Cardiomyocytes Induced by Endothelin-1 through the Protein Kinase C-Dependent but Src and Ras-Independent Pathways

Hypertension Research - Clinical and Experimental

Volumn 22, Issue 2, 1999, Pages 113-119

  Yamazaki, Tsutomu ^a  

^a Department of Cardiovascular Medicine ^*  (Japan)

Author keywords

Cardiac hypertrophy; Endothelin; Extracellular signal regulated protein kinase; Signal transduction

Indexed keywords

CALPHOSTIN C; ENDOTHELIN 1; HEMAGGLUTININ; MITOGEN ACTIVATED PROTEIN KINASE; PROTEIN KINASE C; PROTEIN TYROSINE KINASE; PROTEIN TYROSINE KINASE INHIBITOR; RAS PROTEIN;

ANIMAL CELL; ARTICLE; CONTROLLED STUDY; ENZYME ACTIVATION; ENZYME INHIBITION; HEART CELL CULTURE; HEART MUSCLE CELL; HEART VENTRICLE HYPERTROPHY; MUSCLE STRETCHING; NEWBORN; NONHUMAN; PROTEIN SYNTHESIS; RAT; SIGNAL TRANSDUCTION;

AMINO ACIDS; ANIMALS; CARDIOMEGALY; CELLS, CULTURED; DNA; ENDOTHELIN-1; HEART; MYELIN BASIC PROTEINS; MYOCARDIUM; PLASMIDS; PROTEIN KINASE C; PROTO-ONCOGENE PROTEINS C-RAF; RAS PROTEINS; RATS; RATS, WISTAR; SRC-FAMILY KINASES; TRANSFECTION;

EID: 0032779304     PISSN: 09169636     EISSN: None     Source Type: Journal    
DOI: 10.1291/hypres.22.113     Document Type: Article

References (50)

1. Yanagisawa M, Kurihara H, Kimura S, et al: A novel potent vasoconstrictor peptide produced by vascular endothelial cells. Nature 1988; 332: 411-415.
2. Battistini B, Chauler P, D'Orleans JP, Briere N, Sirois P: Growth regulatory properties of endothelins. Peptides 1993; 14: 385-399.
3. Arai H, Hori S, Aramori I, Ohokubo H, Nakanishi S: Cloning and expression of a cDNA encoding an endothelin receptor. Nature 1990; 348: 730-732.
4. Sakurai T, Yanagisawa M, Takuwa Y, et al: Cloning of a non-isopeptide-selective subtype of the endothelin receptor. Nature 1990; 348: 732-735.
5. Lin HY, Kaji EH, Winkel GK, Ives HE, Lodish HF: Cloning and functional expression of a vascular smooth muscle endothelin 1 receptor. Proc Natl Acad Sei USA 1991; 88: 3185-3189.
6. Hosöda K, Nakao K, Arai H, et al: Cloning and expression of human endothelin-1 receptor cDNA. FEES Lett 1991; 289: 23-26.
7. Komuro I, Kurihara H, Sugiyama T, Yoshizumi M, Takaku F, Yazaki Y: Endothelin stimulates c-fos and c-myc expression and proliferation of vascular smooth muscle cells. FEES Lett 1988; 238: 249-252.
8. Suzuki T, Hoshi H, Mitsui Y: Endothelin stimulates hypertrophy and contractility of neonatal rat cardiac myocytes in a serum-free medium. FEBS Lett 1990; 268: 149-151.
9. Ito H, Hirata Y, Hiroe M, et al: Endothelin-1 induces hypertrophy with enhanced expression of muscle-specific genes in cultured neonatal rat cardiomyocytes. Circ Res 1991; 69: 209-215.
10. Sugden PH, Fuller SJ, Mynett JR, Hatchett RJ 4th, Bogoyevitch MA, Sugden MC: Stimulation of adult rat ventricular myocyte protein synthesis and phosphoinositide hydrolysis by the endothelins. Biochim BiophysActa 1993; 1175: 327-332.
11. Yamazaki T, Komuro I, Kudoh S, et al: Endothelin-1 is involved in mechanical stress-induced cardiomyocyte hypertrophy. J Biol Chem 1996; 271: 3221-3228.
12. Yamazaki T, Komuro I, Kudoh S, et al: Mechanical stress activates protein kinase cascade of phosphorylation in neonatal rat cardiac myocytes. J Clin Invest 1995; 96: 438-446.
13. Yamazaki T, Tobe K, Höh E, et ah Mechanical loading activates mitogen-activated protein kinase and S6 peptide kinase in cultured rat cardiac myocytes. J Biol Chem 1993; 268: 12069-12076.
14. Simpson P, Savion S: Differentiation of rat myocytes in single cell cultures with and without proliferating nonmyocardial cells. Circ Res 1982; 50: 101-116.
15. Tobe K, Kadowaki T, Tamemoto H, et ah Insulin and 12-O-tetradecanoylphorbol-13-acetate activation of two immunologically distinct myelin basic protein/microtubule-associated protein 2 (MBP/MAP2) kinases via de novo phosphorylation of threonine and tyrosine residues. / Biol Chem 1991; 266: 2479324803.
16. Minden A, Lin A, McMahon M, et ah Differential activation of ERK and JNK mitogen-activated protein kinases by Raf-1 and MEKK. Science 1994; 266: 1719-1723.
17. Hata A, Sabe H, Kurosaki T, Takata M, Hanafusa - H: Functional analysis of Csk in signal transduction through the B-cell antigen receptor. Mol Cell Biol 1994; 14: 7306-7313.
18. Kikuchi A, Kaibuchi K, Hori Y, et al: Molecular cloning of the human cDNA for a stimulatory GDP/ GTP exchange protein for c-Ki-ras p21 and smg p21. Oncogene 1992; 7: 289-293.
19. Izumi T, Tamemoto H, Nagao M, Kadowaki T, Takaku F, Kasuga M: Insulin and platelet derived growth factor stimulate phosphorylation of the c-raf product at serine and threonine residues in intact cells. J Dial Chem 1991; 266: 7933-7939.
20. Zou Y, Komuro I, Yamazaki T, et al: Protein kinase C, but not tyrosine kinases or Ras, plays a critical role in angiotensin II-induced activation of Raf-1 kinase and extracellular signal-regulated protein kinases in cardiac myocytes. J Biol Chem 1996; 271: 33592-33597.
21. Pages G, Lenormand P, L'allemain G, Chambard JC, Meloche S, Pouyssegur J: Mitogen-activated protein kinases p42mapk and p44mapk are required for fibroblast proliferation. Proc Natl Acad Sei USA 1993; 90: 8319-8323.
22. Cowley S, Paterson H, Kemp P, Marshall CJ: Activation of MAP kinase kinase is necessary and sufficient for PC12 differentiation and for transformation of NIH 3T3 cells. Cell 1994; 77: 841-852.
23. Okada M, Nada S, Yamanashi Y, Yamamoto T, Nakagawa H: CSK: a protein-tyrosine kinase involved in regulation of src family kinases. J Biol Chem 1991; 266: 24249-24252.
24. Blenis J: Signal transduction via the MAP kinases: proceed at your own RSK. Proc Natl Acad Sei USA 1993; 90: 5889-5892.
25. Satoh T, Nakafuku M, Kaziro Y: Function of Ras as a molecular switch in signal transduction. / Biol Chem 1992; 267: 24149-24152.
26. Thorburn A, Thorburn J, Chen S-Y, et al: HRas-dependent pathways can activate morphological and genetic markers of cardiac muscle cell hypertrophy. J Biol Chem 1993; 268: 2244-2249.
27. Sadoshima J, Izumo S: The heterotrimetric Gq protein-coupled angiotensin II receptor activates p21ras via the tyrosine kinase-Shc-Grb2-Sos pathway in cardiac myocytes. EMBO J 1996; 15: 775-787.
28. Kyriakis JM, App H, Zhang X, et al: Raf-1 activates MAP kinase-kinase. Nature 1992; 358: 417-421.
29. Nishida E, Gotoh Y: The.MAP kinase cascade is essential for diverse signal transduction pathways. Trends Biochem Sei 1993; 18: 128-131.
30. Bogoyevitch MA, Glennon PE, Andersson MB, et al: Endothelin-1 and fibroblast growth factors stimulate the mitogen-activated protein kinase signaling cascade in cardiac myocytes: the potential role of the cascade in the integration of two signaling pathways leading to myocyte hypertrophy. / Biol Chem 1994; 269: 1110-1119.
31. Malarkey K, Chilvers ER, Lawson MF, Plevin R: Stimulation by endothelin-1 of mitogen-activated protein kinases and DNA synthesis in bovine trachéal smooth muscle cells. Br J Pliarmacol 1995; 116: 2267-2273.
32. Cadwallader K, Beltman J, McCormick F, Cook S: Differential regulation of extracellular signal-regulated protein kinase 1 and Jun N-terminal kinase 1 by Ca2+ and protein kinase C in endothelin-stimulated Rat-1 cells. Biochem J 1997; 321 (Pt 3): 795804.
33. Thorburn J, Frost JA, Thorburn A: Mitogen-activated protein kinases mediate changes in gene expression, but not cytoskeletal organization associated with cardiac muscle cell hypertrophy. J Cell Biol 1994; 126: 1565-1572.
34. Post GR, Goldstein D, Thuerauf DJ, Glembotski CC, Brown JH: Dissociation of p44 and p42 mitogenactivated protein kinase activation from receptor-induced hypertrophy in neonatal rat ventricular myocytes. J Biol Cliem 1996; 271: 8452-8457.
35. Post GR, Brown JH: G protein-coupled receptors and signaling pathways regulating growth responses. FASEB J 1996; 10: 741-749.
36. Wu J, Dent P, Jelinek T, Wolfman A, Weber MJ, Sturgill TW: Inhibition of the EGF-activated MAP kinase signaling pathway by adenosine 3′,5′-cyclic monophosphate. Science 1993; 262: 1065-1069.
37. Cook SJ, McCormick F: Inhibition by cAMP of Rasdependent activation of Raf. Science 1993; 262: 10691072.
38. Graves LM, Bornfeldt KE, Raines EW, et al: Protein kinase A antagonizes platelet-derived growth factorinduced signaling by mitogen-activated protein kinase in human arterial smooth muscle cells. Proc Natl AcadSci USA 1993; 90: 10300-10304.
39. Sevetson BR, Kong X, Lawrence JC: Increasing cAMP attenuates activation of mitogen-activated protein kinase. Proc Natl Acad Sei USA 1993; 90: 10305-10309.
40. Burgering BMT, Pronk GJ, Weeren PC, Chardin P, Bos JL: cAMP antagonizes p21ras-directed activation of extracellular signal-regulated kinase 2 and phosphorylation of mSos nucleotide exchange factor. EMBOJ1993; 12: 4211-4220.
41. Rüssel M, Winitz S, Johnson GL: Acetylcholine muscarinic Ml receptor regulation of cyclic AMP synthesis controls growth factor stimulation of Raf activity. Mol Cell Biol 1994; 14: 2343-2351.
42. Fuller SJ, Davies EL, Gillespie BJ, Sun H, Tonks NK: Mitogen-activated protein kinase phosphatase 1 inhibits the stimulation of gene expression by hypertrophic agonists in cardiac myocytes. Biochem J 1997; 323: 313-319.
43. Komuro I, Kaida T, Shibazaki Y, Kurabayashi M, Takaku F, Yazaki Y: Stretching cardiac myocytes stimulates proto-oncogene expression. J Biol Cliem 1990; 265: 3595-3598.
44. Komuro I, Katoh Y, Kaida T, et al: Mechanical loading stimulates cell hypertrophy and specific gene expression in cultured rat cardiac myocytes. J Biol Chem 1991; 266: 1265-1268.
45. Yamazaki T, Komuro I, Yazaki Y: Molecular mechanism of cardiac cellular hypertrophy by mechanical stress. J Mol Cell Cardiol 1995; 27: 133-140.
46. Pause A, Belsham GJ, Gingras AC, et al: Insulin-dependent stimulation of protein synthesis by phosphorylation of a regulator of 5'-cap function. Nature 1994; 371: 762-767.
47. Haystead TA, Haystead CM, Hu C, Lin TA, Lawrence JJ: Phosphorylation of PHAS-I by mitogenactivated protein (MAP) kinase. Identification of a site phosphorylated by MAP kinase in vitro and in response to insulin in rat adipocytes. J Biol Chem 1994; 269: 23185-23191.
48. Wada H, Ivester CT, Carabello BA, Cooper IV G, McDermott PJ: Translational initiation factor eIF-4E. J Biol Chem 1996; 271: 8359-8364.
49. Parker T, Schneider M: Growth factors, protooncogenes, and plasticity of the cardiac phenotype. Annu Rev Pliysiol 1991; 53: 179-200.
50. Daub H, Weiss FU, Wallasch C, Ullrich A: Role of transactivation of the EGF receptor in signalling by G-protein-coupled receptors. Nature 1996; 379: 557560.