Genetics of susceptibility to infectious diseases: Tuberculosis and leprosy as examples

Drug Metabolism and Disposition

Volumn 29, Issue 4 II, 2001, Pages 479-483

  Marquet, S ^a   Schurr, E ^a  

^a MONTREAL GENERAL HOSPITAL   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

GAMMA INTERFERON RECEPTOR; HLA DQ ANTIGEN; HLA DR ANTIGEN; INTERLEUKIN 1 RECEPTOR BLOCKING AGENT; INTERLEUKIN 12; INTERLEUKIN 1BETA; MAJOR HISTOCOMPATIBILITY ANTIGEN CLASS 2; MANNOSE BINDING PROTEIN; NATURAL RESISTANCE ASSOCIATED MACROPHAGE PROTEIN 1; TUMOR NECROSIS FACTOR; UNCLASSIFIED DRUG; VITAMIN D RECEPTOR;

CONFERENCE PAPER; GENE MUTATION; GENETIC ANALYSIS; GENETIC LINKAGE; GENETIC SUSCEPTIBILITY; HUMAN; INFECTION SENSITIVITY; LEPROSY; MYCOBACTERIUM TUBERCULOSIS; NONHUMAN; PATHOGENESIS; PRIORITY JOURNAL; TUBERCULOSIS;

ANIMALS; DISEASE MODELS, ANIMAL; GENETIC PREDISPOSITION TO DISEASE; HUMANS; LEPROSY; MICE; TUBERCULOSIS;

MYCOBACTERIUM; MYCOBACTERIUM TUBERCULOSIS;

EID: 0035062376     PISSN: 00909556     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Conference Paper

References (39)

1. Susceptibility to leprosy is linked to the human NRAMPI gene
2. Impairment of mycobacterial immunity in human interleukin-12 receptor deficiency
3. A causative relationship between mutant IFNgRI alleles and impaired cellular response to IFNgamma in a compound heterozygous child
4. Mendelian susceptibility to mycobacterial infection in man
5. Inherited interleukin 12 deficiency in a child with bacille Calmette-Guerin and Salmonella enteritidis disseminated infection
6. Tuberculosis and chronic hepatitis B virus infection in Africans and variation in the vitamin D receptor gene
7. Variations in the NRAMPI gene and susceptibility to tuberculosis in West Africans
8. Association of tuberculosis and M. tuberculosis-specific antibody levels with HLA
9. Association of pulmonary tuberculosis and HLA in south India
10. Severe mycobacterial and Salmonella infections in interleukin-12 receptor-deficient patients
11. Mutation in the signal-transducing chain of the interferon-gamma receptor and susceptibility to mycobacterial infection
12. Association of an HLA-DQ allele with clinical tuberculosis
13. Genetic epidemiology of tuberculosis susceptibility and analysis of linkage to chromosome 2q35 near NRAMPI in a large Aboriginal Canadian family
14. Mannose-binding protein B allele confers protection against tuberculous meningitis
15. Interferon-gamma-receptor deficiency in an infant with fatal bacille Calmette-Guerin infection
16. Partial interferon-gamma receptor I deficiency in a child with tuberculoid bacillus Calmette-Guerin infection and a sibling with clinical tuberculosis
17. A human IFNGR1 small deletion hotspot associated with dominant susceptibility to mycobacterial infection
18. Tumor necrosis factor and interleukin-1 inhibitors as markers of disease activity of tuberculosis
19. Severity of tuberculosis in mice is linked to distal chromosome 3 and proximal chromosome 9
20. Contribution of trans-acting factor alleles to normal physiological variability: Vitamin D receptor gene polymorphism and circulating osteocalcin
21. A mutation in the interferon-gamma-receptor gene and susceptibility to mycobacterial infection
22. Novel human immunodeficiencies reveal the essential role of type-I cytokines in immunity to intracellular bacteria
23. Fatal disseminated Mycobacterium smegmatis infection in a child with inherited interferon gamma receptor deficiency
24. Study of HLA class II alleles by PCR oligotyping in leprosy patients from north India
25. Associations of HLA-DRB1, DQB1 and DPB1 alleles with pulmonary tuberculosis in south India
26. No evidence for linkage between leprosy susceptibility and the human natural resistance-associated macrophage protein I (NRAMPI) gene in French Polynesia
27. Association of vitamin D receptor genotype with leprosy type
28. Tumor necrosis factor promoter polymorphism and susceptibility to lepromatous leprosy
29. Association of functional mutant homozygotes of the mannose binding protein gene with susceptibility to pulmonary tuberculosis in India
30. An RFLP map for 2q33-q37 from multicase mycobacterial and leishmanial disease families: No evidence for an Lsh/Ity/Bcg gene homologue influencing susceptibility to leprosy
31. Evidence that genetic susceptibility to Mycobacterium tuberculosis in a Brazilian population is under oligogenic control: Linkage study of the candidate genes NRAMPI and TNFA
32. Human leukocyte antigen and leprosy: Study in northern Louisiana and review
33. HLA segregation of tuberculoid leprosy: Confirmation of the DR2 marker
34. The Ity/Lsh/Bcg locus: Natural resistance to infection with intracellular parasites is abrogated by disruption of the Nramp1 gene
35. Natural resistance to intracellular infections: Nramp1 encodes a membrane phosphoglycoprotein absent in macrophages from susceptible (Nramp1 D169) mouse strains
36. Association of leprosy with HLA-DR2 in a Southern Brazilian population
37. Influence of polymorphism in the genes for the interleukin (IL)-I receptor antagonist and IL-Ibeta on tuberculosis
38. Influence of vitamin D deficiency and vitamin D receptor polymorphisms on tuberculosis among Gujarati Asians in west London: A case-control study
39. Arginine at positions 13 or 70-71 in pocket 4 of HLA-DRB 1 alleles is associated with susceptibility to tuberculoid leprosy