No Evidence for Linkage between Leprosy Susceptibility and the Human Natural Resistance-Associated Macrophage Protein 1 (NRAMP1) Gene in French Polynesia

International Journal of Leprosy and Other Mycobacterial Diseases

Volumn 65, Issue 2, 1997, Pages 197-202

  Roger, Michel ^a   Levee, Geraldine ^b   Chanteau, Suzanne ^b   Gicquel, Brigitte ^c   Schurr, Erwin ^a  

^a MONTREAL GENERAL HOSPITAL   (Canada)

^b Inst Terr Rech Medicales Louis M   (French Polynesia)

^c INSTITUT PASTEUR   (France)

Author keywords

[No Author keywords available]

Indexed keywords

ARTICLE; DISEASE PREDISPOSITION; GENETIC LINKAGE; GENOTYPE; HUMAN; LEPROSY; MAJOR CLINICAL STUDY; MYCOBACTERIUM LEPRAE; POLYNESIA;

ALLELES; CARRIER PROTEINS; CATION TRANSPORT PROTEINS; FEMALE; GENETIC PREDISPOSITION TO DISEASE; HUMANS; LEPROSY; LINKAGE (GENETICS); LOD SCORE; MALE; MEMBRANE PROTEINS; MICROSATELLITE REPEATS; PEDIGREE; POLYMERASE CHAIN REACTION; POLYMORPHISM, GENETIC; POLYNESIA;

EID: 0030802663     PISSN: 0148916X     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (18)

1. ABEL, L., LAP, V. D., OBERTI, J., THUC, N.V., CUA, V. V., GUILLOUD-BATAILLE, M., SCHURR, E. and LAGRANGE, P.H. Complex segregation analysis of leprosy in Southern Vietnam. Genet. Epidemiol. 12 (1995) 63-82.
2. BUU, N. T., CELLIER, M., GROS, P. and SCHURR, E. Identification of highly polymorphic length variant in the 3 UTR of NRAMP1. Immunogenetics 42 (1995) 428-429.
3. CELLIER, M., GOVONI, G., VIDAL, S. M., KWAN, T., GROULX, N., LIU, J., SANCHEZ, F., SKAMENE, E., SCHURR, E. and GROS, P. Human natural resistance-associated macrophage protein. c-DNA cloning, chromosomal mapping, genomic organization and tissue-specific expression. J Exp. Med. 180 (1994) 1741-1752.
4. DE VRIES, R. R. P., NIJENHUIS, L. E., LAI A FAT, R. F. M. and VAN ROOD, J. J. HLA-linked genetic control of host response to Mycobacterium leprae. Lancet 2 (1976) 1328-1330.
5. FEITOSA, M. F., BORECKI, I., KREIGER, H., BEIGUELMAN, B. and RAO, D. C. The genetic epidemiology of leprosy in Brazilian population. Am. J. Hum. Genet. 56 (1995) 1179-1185.
6. FLINT, J., BOYCE, A. J., MARTINSON, J. J. and CLEGG, J. B. Population bottlenecks in Polynesia revealed by minisatellites. Hum. Genet 83 (1989) 257-263.
7. HERTZBERG, M. S., MICKLESON, K. N. P. and TRENT, R. J. Limited genetic diversity in Polynesians reflected in the highly polymorphic 3 'HVR-globin gene marker. Hum. Hered. 42 (1992) 157-161.
8. LATHROP, G. M., LALOUEL, J. M., JULIER, C. and OTT, J. Strategies for multilocus linkage analysis in humans. Proc. Natl. Acad. Sci. U.S.A. 81 (1984) 3443-3446.
9. LEVEE, G., LIU, J , GICQUEL, B., CHANTEAU, S. and SCHURR, E. Genetic control of susceptibility to leprosy in French Polynesia; no evidence for linkage with markers on the telomeric human chromosome 2. Int. J. Lepr. 62 (1994) 499-511.
10. LIU, J., FUJIWARA, T. M., BUU, N. T., SANCHEZ, F. O., CELLIER, M., PARADIS, A. J., FRAPPIER, D., SKAMENE, E., GROS, P., MORGAN, K. and SCHURR, E. Identification of polymorphisms and sequence variants in the human homologue of the mouse natural resistance-associated macrophage protein gene. Am. J. Hum. Genet. 56 (1995) 845-853.
11. MARTINSON, J. J., HARDING, R. M., PHILIPPON, G., FLYE SAINTE-MARIE, F., ROUX, J., BOYCE, A. J. and CLEGG, J. B. Demographic reductions and genetic bottlenecks in humans: minisatellite allele distributions in Oceania. Hum. Genet. 91 (1993) 445-450.
12. OTTENHOFF, T. H. and DE VRIES, R. R. P. HLA class II immune response and suppression genes in leprosy. Int. J. Lepr. 55 (1987) 521-534.
13. SCHURR, E., BUSCHMAN, E., MALO, D., GROS, P. and SKAMENE, E. Immunogenetics of mycobacterial infections: mouse-human homologies. J. Infect. Dis. 161 (1990) 634-641.
14. SERJEANTSON, S. HLA and susceptibility to leprosy. Immunol. Rev. 70 (1983) 89-112.
15. SHAW, A. M. ATKINSON, S., DOCKRELL, H., HUSSAIN, R., LINS-LAINSON, Z., SHAW, J., RAMOS, F., SILVEIRA, F., MEHDI, S. Q., KAUKAB, F., KHALIQ, S., CHIANG, T. and BLACKWELL, J. An RFLP map for 2q33-q37 from multicase mycobacterial and leishmanial disease families: no evidence for an Lsh/Ity/Bcg gene homologue influencing susceptibility to leprosy. Ann. Hum. Genet. 57 (1993) 251-271.
16. SHIELDS, E. D., RUSSELL, D. A. and PERICAK-VANCE, M. A. Genetic epidemiology of the susceptibility to leprosy. J. Clin. Invest. 79 (1987) 1139-1143.
17. VAN EDEN, W. and DE VRIES, R. R. P. HLA and leprosy: a reevaluation. Lepr. Rev. 55 (1984) 89-104.
18. VIDAL, S. M., MALO, D., VOGAN, K., SKAMENE, E. and GROS, P. Natural resistance to infection with intracellular parasites: isolation of a candidate for Bcg. Cell 73 (1993) 469-485.