Characterization of cerebrosides from the thermally dimorphic mycopathogen Histoplasma capsulatum: Expression of 2-hydroxy fatty N-acyl (E)-Δ3-unsaturation correlates with the yeast-mycelium phase transition

Glycobiology

Volumn 11, Issue 2, 2001, Pages 113-124

  Toledo, Marcos S ^a,b   Levery, Steven B ^a,b   Suzuki, Erika ^a,b   Straus, Anita H ^a,b   Takahashi, Helio K ^a,b  

^a FEDERAL UNIVERSITY OF SÃO PAULO   (Brazil)

^b UNIVERSITY OF GEORGIA   (United States)

Author keywords

Fungus; Glucosylceramide; Glycosphingolipid; Thermal dimorphism; Yeast

Indexed keywords

BETA GLUCOPYRANOSYLCERAMIDE; CARBOHYDRATE DERIVATIVE; CERAMIDE DERIVATIVE; CEREBROSIDE; DECANOIC ACID DERIVATIVE; ENZYME; GLUCOSYLCERAMIDE; GLYCOSPHINGOLIPID; GLYCOSYLINOSITOL PHOSPHORYLCERAMIDE; HYDROXY FATTY ACID; LIPID; N 2' HYDROXYOCTADECANOATE; PHYTOSPHINGOSINE; UNCLASSIFIED DRUG;

ARTICLE; BIOSYNTHESIS; CARBOHYDRATE ANALYSIS; CHEMICAL MODIFICATION; CHEMOTAXONOMY; CONTROLLED STUDY; CORRELATION FUNCTION; FATTY ACID DESATURATION; HISTOPLASMA CAPSULATUM; HYPOTHESIS; MASS SPECTROMETRY; MOLECULAR WEIGHT; MORPHOLOGY; MYCELIUM; NONHUMAN; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; PHASE TRANSITION; PRIORITY JOURNAL; PURIFICATION; SEX DIFFERENCE; TANDEM MASS SPECTROMETRY; THERMAL STIMULATION; YEAST;

CARBOHYDRATE CONFORMATION; CEREBROSIDES; CHROMATOGRAPHY, THIN LAYER; FATTY ACID DESATURASES; HISTOPLASMA; NUCLEAR MAGNETIC RESONANCE, BIOMOLECULAR; SPECTROMETRY, MASS, ELECTROSPRAY IONIZATION;

AJELLOMYCES CAPSULATUS; FUNGI; SPHINGIODEA;

EID: 0035057949     PISSN: 09596658     EISSN: None     Source Type: Journal    
DOI: 10.1093/glycob/11.2.113     Document Type: Article

References (80)

1. Structure determination of sphingolipids by mass spectrometry
2. Different protein kinase C isoforms are present in the yeast and mycelium forms of Sporothrix schenckii
3. A new cerebroside from Fusicoccum amygdali Del
4. Identification of fuz7, a U stilago maydis MEK/MAPKK homolog required for a-locus-dependent and -independent steps in the fungal life cycle
5. Carbohydrate structures of three novel phosphoinositol-containing sphingolipids from the yeast Histoplasma capsulatum
6. Occurrence of novel antigenic phosphoinositol-containing sphingolipids in the pathogenic yeast Histoplasma capsulatum
7. MLEV-17-based two-dimensional homonuclear magnetization transfer spectroscopy
8. 1H-detected heteronuclear multiple-bond correlation spectroscopy
9. 13C assignments from sensitivity-enhanced detection of heteronuclear multiple-bond connectivity by 2D multiple quantum NMR
10. Natural abundance nitrogen-15 NMR by enhanced heteronuclear spectroscopy
11. Coherence transfer by isotropic mixing: Application to proton correlation spectroscopy
12. Glycolipids from sponges. I. Glycosyl ceramide composition of the marine sponge Agelas clathrodes
13. Glycolipids from sponges. III. Glycosyl ceramides from the marine sponge Agelas conifera
14. Tandem mass spectrometry of glycolipids
15. The structures of polysaccharides and glycolipids of Aspergillus fumigatus grown in the presence of human serum
16. 13C NMR analysis of galactosylceramides
17. 1H nuclear magnetic resonance spectroscopy
18. Biochemistry, cell biology and molecular biology of lipids of Saccharomyces cerevisiae
19. Experiments for recording pure-absorption heteronuclear correlation spectra using pulsed field gradients
20. Sphingolipid functions in Saccharomyces cerevisiae: Comparison to mammals
21. Yeast sphingolipids
22. Reduced virulence of Candida albicans MKC1 mutants: A role for mitogen- activated protein kinase in pathogenesis
23. Fungal infections: A growing threat
24. Ceramide-activated protein phosphatase: Partial purification and relationship to protein phosphatase 2A
25. Structure elucidation of glycosphingolipids and gangliosides using high-performance tandem mass spectrometry
26. Analysis of derivatized ceramides and neutral glycosphingolipids by high-performance tandem mass spectrometry
27. Structural characterization of neutral glycosphingolipids from Fusarium species
28. Fungal infections in HIV-infected patients
29. Isolation of N-2′-hydroxyhexadecanoyl-1-O-β-D-glucopyranosyl-9 -methyl-D-erythro-sphingadienine from fruiting bodies of two Basidiomycetes fungi
30. Structure of cerebroside in Aspergillus oryzae
31. Germ tube growth of Candida albicans
32. Bifunctional role of glycosphingolipids. Modulators for transmembrane signaling and mediators for cellular interactions
33. Sphingolipid-dependent protein kinases
34. Gangliosides and glycosphingolipids as modulators of cell growth, adhesion, and transmembrane signaling
35. The novel second messenger ceramide: Identification, mechanism of action, and cellular activity
36. Molecular cloning and expression of mouse ceramide glucosyltransferase
37. Expression cloning of a cDNA for human ceramide glucosyltransferase that catalyzes the first glycosylation step of glycosphingolipid synthesis
38. Ophidiacerebrosides: Cytotoxic glycosphingolipids containing a novel sphingosine from a sea star
39. Conserved domains of glycosyltransferases
40. Characterization of cerebroside (monoglycosylceramide) from the sea anemone, Metridium senile
41. Molecular species of cerebrosides in fruiting bodies of Lentinus edodes and their biological activity
42. Fruiting-inducing activity of cerebrosides observed with Schizophyllum commune
43. Chemistry and functional moiety of a fruiting-inducing cerebroside in Schizophyllum commune
44. Structure of biologically active and inactive cerebrosides prepared from Schizophyllum commune
45. Fruiting of Schizophyllum commune induced by certain ceramides and cerebrosides from Penicillium funiculosum
46. Cerebrosides A and C, sphingolipid elicitors of hypersensitive cell death and phytoalexin accumulation in rice plants
47. Sphingolipids-their metabolic pathways and the pathobiochemistry of neurodegenerative diseases
48. Structure elucidation of sphingolipids from the mycopathogen Paracoccidioides brasiliensis: An immunodominant β-galactofuranose residue is carried by a novel glycosylinositol phosphorylceramide antigen
49. + adduct ions
50. Fill, a G-protein alpha-subunit that acts upstream of cAMP and is essential for dimorphic switching in haploid cells of Ustilago hordei
51. Endemic mycoses: A treatment update
52. Rustmicin, a potent antifungal agent, inhibits sphingolipid synthesis at the inositol phosphoceramide synthase
53. Khafrefungin, a novel inhibitor of sphingolipid synthesis
54. Signal transduction of stress via ceramide
55. Cerebroside of the dimorphic human pathogen, Candida albicans
56. A mushroom fruiting body-inducing substance inhibits activities of replicative DNA polymerases
57. Sphingolipid synthesis as a target for antifungal drugs. Complementation of the inositol phosphorylceramide synthase defect in a mutant strain of Saccharomyces cerevisiae by the AUR1 gene
58. Agelasphins, novel antitumor and immunostimulatory cerebrosides from the marine sponge Agelas mauritianus
59. Elements of a single MAP kinase cascade in Saccharomyces cerevisiae mediate two developmental programs in the same cell type: Mating and invasive growth
60. Lovastatin triggers an apoptosis-like cell death process in the fungus Mucor racemosus
61. The location of double bonds in a cerebroside from edible fungi (mushroom) estimated by B/E linked scan fast atom bombardment mass spectrometry
62. Sphingolipids and glycerolipids. I. Chemical structures and Ionophoretic activities of soya-cerebrosides I and II from soybean
63. Isolation and structure determination of Pachybasium cerebrosides which potentiate the antifungal activity of aculeacin
64. 5 fusion protein
65. The role of sphingosine in cell growth regulation and transmembrane signaling
66. Structure determination of soybean and wheat glucosylceramides by tandem mass spectrometry
67. Chromatography on silica gel columns
68. Biological properties of Aureobasidin A, a cyclic depsipeptide antifungal antibiotic
69. 3-unsaturation in cerebrosides of Paracoccidioides brasiliensis and Aspergillus fumigatus
70. Dimorphic expression of cerebrosides in the mycopathogen Sporothrix schenckii
71. Glycolipids from Paracoccidioides brasiliensis. Isolation of a galactofuranose-containing glycolipid reactive with sera of patients with paracoccidioidomycosis
72. Signaling pathways for transduction of the initial message of the glycocode into cellular responses
73. Structural determination of N-2′-hydroxyoctadecenoyl-1-O-β-D-glucopyranosyl-9-methyl-4, 8-sphingadienine from species of Aspergillus
74. Treatment of fungal and other opportunistic infections in immunocompromised patients
75. Recent progress and current problems in treatment of invasive fungal infections in neutropenic patients
76. Isolation and composition of inositolphosphorylceramide-type sphingolipids of hyphal forms of Candida albicans
77. A Candida albicans RAS-related gene (CaRSR1) is involved in budding, cell morphogenesis and hypha development
78. 1H-NMR studies on glycosphingolipids