Isolation and composition of inositolphosphorylceramide-type sphingolipids of hyphal forms of Candida albicans

Journal of Bacteriology

Volumn 178, Issue 21, 1996, Pages 6223-6226

  Wells, Gerald B ^a   Dickson, Robert C ^a   Lester, Robert L ^a,b  

^a UNIVERSITY OF KENTUCKY   (United States)

^b UNIVERSITY OF KENTUCKY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CERAMIDE DERIVATIVE; INOSITOL; PHOSPHORUS; SPHINGOLIPID; SPHINGOSINE;

ARTICLE; CANDIDA ALBICANS; CHEMICAL STRUCTURE; CHROMATOGRAPHY; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; LIPID COMPOSITION; LIPID MEMBRANE; MEMBRANE BINDING; PRIORITY JOURNAL; STRUCTURE ANALYSIS;

ANIMALIA; CANDIDA ALBICANS; SACCHAROMYCES CEREVISIAE;

EID: 0029858703     PISSN: 00219193     EISSN: None     Source Type: Journal    
DOI: 10.1128/jb.178.21.6223-6226.1996     Document Type: Article

References (17)

1. Bartlett, G. R. 1959. Phosphorus assay in column chromatography. J. Biol. Chem. 234:465-468.
2. Bullock, W., T. Kozel, S. Scherer, and D. M. Dixon. 1993. Medical mycology in the 1990s: involvement of NIH and the wider community. ASM News 59:182-185.
3. Dickson, R. C., G. B. Wells, A. Schmidt, and R. L. Lester. 1990. Isolation of mutant Saccharomyces cerevisiae strains that survive without sphingolipid. Mol. Cell. Biol. 19:2175-2181.
4. Fewster, M. E., B. J. Burns, and J. F. Mead. 1969. Quantitative densitometric thin-layer chromatography of lipids using copper acetate reagent. J. Chromatogr. 43:120-126.
5. Hanson, B. A., and R. L. Lester. 1980. The extraction of inositol-containing phospholipids and phosphatidylcholine from Saccharomyces cerevisiae and Neurospora crassa. J. Lipid Res. 21:309-315.
6. Lester, R. L., and R. C. Dickson. 1993. Sphingolipids with Inositolphosphate-containing head groups. Adv. Lipid Res. 26:253-274.
7. Lester, R. L., G. B. Wells, G. Oxford, and R. C. Dickson. 1993. Mutant strains of Sacchromyces cerevisiae lacking sphingolipids synthesize novel inositol glycerophospholipids that mimic sphingolipid structures. J. Biol. Chem. 268: 845-856.
8. Mandala, S. M., K. A. Thornton, B. R. Frommer, J. E. Curotto, W. Rozdilsky, M. B. Kurtz, R. A. Giacobbe, G. F. Bills, M. A. Cabello, I. Martin, F. Peláez, and G. H. Harris. 1995. The discovery of australifungin, a novel inhibitor of sphinganine N-acyltransferase from Sporormiella australis, producing organism, fermentation, isolation, and biological activity. J. Antibiot. 48:349-356.
9. Patton, J. L., and R. L. Lester. 1991. The phosphoinositol sphingolipids of Saccharomyces cerevisiae are highly localized in the plasma membrane. J. Bacteriol. 173:3101-3108.
10. Patton, J. L., B. Srinivasan, R. C. Dickson, and R. L. Lester. 1992. Phenotypes of sphingolipid-dependent strains of Saccharomyces cerevisiae. J. Bacteriol. 174:7180-7184.
11. Pinto, W., J. B. Srinivasan, S. Shepherd, A. Schmidt, R. C. Dickson, and R. L. Lester. 1992. Sphingolipid long-chain-base auxotrophs of Sacchoromyces cerevisiae: genetics, physiology, and a method for their selection. J. Bacteriol. 174:2565-2574.
12. Skipski, V. P., and M. Barclay. 1969. Thin layer chromatography of lipids. Methods Enzymol. 14:545-546.
13. Smith, S. W., and R. L. Lester. 1974. Inositolphosphorylceramide, a novel substance and the chief member of a major group of yeast sphingolipids containing a single inositol phosphate. J. Biol. Chem. 249:3395-3405.
14. Vincent, V. L., and L. S. Klig. 1995. Unusual effect of myo-inositol on phospholipid synthesis in Cryptococcus neoformans. Microbiology 141:1829-1837.
15. Wells, G. B., and R. L. Lester. 1983. The isolation and characterization of a mutant strain of Saccharomyces cerevisiae that requires a long chain base for growth and for synthesis of phosphosphingolipids. J. Biol. Chem. 258:10200-10203.
16. Wood, R., and T. Lee. 1983. High-performance liquid chromatography of fatty acids: quantitative analysis of saturated, monoenoic, polyenoic and geometrical isomers. J. Chromatogr. 254:237-246.
17. Zweerink, M. M., A. M. Edison, G. B. Wells, W. Pinto, and R. L. Lester. 1992. Characterization of a novel, potent, and specific inhibitor of serine palmitoyltransferase. J. Biol. Chem. 267:25032-25038.