HMG box a in HMG2 protein functions as a mediator of DNA structural alteration together with box B

Journal of Biochemistry

Volumn 129, Issue 4, 2001, Pages 643-651

  Nakamura, Y ^a   Yoshioka, K I ^a   Shirakawa, H ^a   Yoshida, M ^a  

^a TOKYO UNIVERSITY OF SCIENCE   (Japan)

Author keywords

DNA bending; DNA kinking; DNA unwinding; HMG box; HMG2 protein

Indexed keywords

CURVED DNA; DNA BINDING PROTEIN; NONHISTONE PROTEIN; SINGLE STRANDED DNA BINDING PROTEIN;

AMINO ACID SEQUENCE; ARTICLE; CYCLIZATION; DNA BINDING; DNA DETERMINATION; DNA STRUCTURE; POLYACRYLAMIDE GEL ELECTROPHORESIS; PROTEIN ANALYSIS;

EID: 0035050208     PISSN: 0021924X     EISSN: None     Source Type: Journal    
DOI: 10.1093/oxfordjournals.jbchem.a002902     Document Type: Article

References (72)

1. Primary structure of non-histone protein HMG1 revealed by the nucleotide sequence
2. Primary structure of non-histone chromosomal protein HMG2 revealed by the nucleotide sequence
3. Structural features of the HMG chromosomal proteins and their genes
4. A signature for the HMG-1 box DNA-binding proteins
5. Role of chromatin structure in the regulation of transcription by RNA polymerase II
6. The HMG-box domain in DNA-Proteins: Structural Interactions
7. High-mobility-group chromosomal proteins: Architectural components that facilitate chromatin function
8. High mobility group proteins 1 and 2 can function as DNA-binding regulatory components for DNA-dependent protein kinase in vitro
9. Novel autoantigens of perinuclear anti-neutrophil cytoplasmic antibodies (P-ANCA) in ulcerative colitis: Non-histone chromosomal proteins, HMG1 and HMG2
10. Prevalence and characterization of perinuclear anti-neutrophil cytoplasmic antibodies (P-ANCA) directed against HMG1 and HMG2 in ulcerative colitis (UC)
11. High mobility group (HMG) non-histone chromosomal proteins HMG1 and HMG2 are significant target antigens of perinuclear anti-neutrophil cytoplasmic antibodies in autoimmune hepatitis
12. Prevalence and characterization of novel pANCA, antibodies to the high mobility group non-histone chromosomal proteins HMG1 and HMG2, in systemic rheumatic diseases
13. High mobility group chromosomal protein I binds to the adeno-associated virus replication protein (Rep) and promotes Rep-mediated site-specific cleavage of DNA, ATPase activity and transcriptional repression
14. Secretion and binding of HMG1 protein to the external surface of the membrane are required for murine erythroleukemia cell differentiation
15. High-mobility group chromatin proteins 1 and 2 functionally interact with steroid hormone receptors to enhance their DNA binding in vitro and transcriptional activity in mammalian cells
16. Estrogen treatment induces elevated expression of HMG1 in MCF-7 cells
17. HMG-1 as a late mediator of endotoxin lethality in mice
18. HMG-1 stimulates estrogen response element binding by estrogen receptor from stably transfected HeLa cells
19. Non-histone chromosomal proteins HMG1 and 2 enhance ligation reaction of DNA double-strand breaks
20. Stimulation of transcription in cultured cells by high mobility group protein 1: Essential role of the acidic carboxyl-terminal region
21. Stimulation of transcription accompanying relaxation of chromatin structure in cells overexpressing high mobility group 1 protein
22. Repression of cell cycle progression by antisense HMG2 RNA
23. DNA binding activity of recombinant SRY from normal males and XY females
24. Short-range DNA looping by the Xenopus HMG-box transcription factor, xUBF
25. The RNA polymerase I transactivator upstream binding factor requires its dimerization domain and high-mobility-group (HMG) box 1 to bend, wrap, and positively super-coil enhancer DNA
26. The DNA supercoiling architecture induced by the transcription factor xUBF requires three of its five HMG-boxes
27. Molecular basis of human 46X,Y sex reversal revealed from the three-dimensional solution structure of the human SRY-DNA complex
28. Molecular basis of mammalian sexual determination: Activation of Mullerian inhibiting substance gene expression by SRY
29. Sex-reversing mutations affect the architecture of SRY-DNA complexes
30. Interaction of normal and mutant SRY proteins with DNA
31. The RNA polymerase I transcription factor UBF is a sequence-tolerant HMG-box protein that can recognize structured nucleic acids
32. xUBF, an RNA polymerase I transcription factor, binds crossover DNA with low sequence specificity
33. DNA-binding properties of the tandem HMG boxes of high-mobility-group protein 1 (HMG1)
34. Difference in affinity for DNA between HMG proteins 1 and 2 determined by surface plasmon resonance measurements
35. Hierarchy of binding sites for chromosomal proteins HMG 1 and 2 in supercoiled deoxyribonucleic acid
36. Chromosomal protein HMG1 removes the transcriptional block caused by the cruciform in supercoiled DNA
37. Differences in DNA recognition and conformational change activity between boxes A and B in HMG2 protein
38. Specific recognition of cruciform DNA by nuclear protein HMG1
39. HMG box proteins bind to four-way DNA junctions in their open conformation
40. Structure-specific binding of the two tandem HMG boxes of HMG1 to four-way junction DNA is mediated by the A domain
41. A role of basic residues and the putative intercalating phenylalanine of the HMG-1 box B in DNA supercoiling and binding to four-way DNA junctions
42. Cruciform DNA binding protein in HeLa cell extracts
43. Nonhistone proteins HMG1 and HMG2 suppress the nucleosome assembly at physiological ionic strength
44. The nonspecific DNA-binding and -bending proteins HMG1 and HMG2 promote the assembly of complex nucleoprotein structures
45. High-mobility-group 1 protein mediates DNA bending as determined by ring closures
46. HMG1 proteins from evolutionary distant organisms distort B-DNA conformation in similar way
47. DNA bending by the chromosomal protein HMG1 and its high mobility group box domains. Effect of flanking sequences
48. High glutamic and aspartic region in nonhistone protein HMG(1+2) unwinds DNA double helical structure
49. Two mutations in the HMG-box with very different structural consequences provide insights into the nature of binding to four-way junction DNA
50. DNA - Protein interactions. Applying a genetic cantilever
51. The stabilized structural array of two HMG1/2-boxes endowed by a linker sequence between them is requisite for the effective binding of HMG1 with DNA
52. DNA looping by the HMG-box domains of HMG1 and modulation of DNA binding by the acidic C-terminal domain
53. The mechanism of sequence non-specific DNA binding of HMG1/2-box B in HMG1 with DNA
54. The specific interactions of HMG 1 and 2 with negatively supercoiled DNA are modulated by their acidic C-terminal domains and involve cysteine residues in their HMG 1/2 boxes
55. Efficient large-scale purification of non-histone chromosomal proteins HMG1 and HMG2 by using polybuffer-exchanger PBE94
56. Characterisation of size variants of type I DNA topoisomerase isolated from calf thymus
57. Sequence-induced DNA curvature at the bacteriophage lambda origin of replication
58. Sequence-directed curvature of DNA
59. Changes in superhelicity are introduced into closed circular DNA by binding of high mobility group protein I/Y
60. DNA curvature influences the internal motions of supercoiled DNA
61. DNA bending induced by high mobility group proteins studied by fluorescence resonance energy transfer
62. The DNA bend angle and binding affinity of an HMG box increased by the presence of short terminal arms
63. The HMG domain of lymphoid enhancer factor 1 bends DNA and facilitates assembly of functional nucleoprotein structures
64. Functional analysis of DNA bending and unwinding by the high mobility group domain of LEF-1
65. SRY, like HMG1, recognizes sharp angles in DNA
66. Protein-directed DNA structure. I. Raman spectroscopy of a high-mobility-group box with application to human sex reversal
67. Determining the DNA bending angle induced by non-specific high mobility group-1 (HMG-1) proteins: A novel method
68. The SRY high-mobility-group box recognizes DNA by partial intercalation in the minor groove: A topological mechanism of sequence specificity
69. An SRY mutation causing human sex reversal resolves a general mechanism of structure-specific DNA recognition: Application to the four-way DNA junction
70. Differences in the DNA-binding properties of the HMG-box domains of HMG1 and the sex-determining factor SRY
71. Bending of DNA by transcription factors
72. Nucleolar transcription factor hUBF contains a DNA-binding motif with homology to HMG proteins