The stabilized structural array of two HMG1/2-boxes endowed by a linker sequence between them is requisite for the effective binding of HMG1 with DNA

Journal of Biochemistry

Volumn 125, Issue 2, 1999, Pages 399-405

  Saito, Kouhei ^a   Kikuchi, Takeshi ^a   Shirakawa, Hitoshi ^a   Yoshida, Michiteru ^a  

^a TOKYO UNIVERSITY OF SCIENCE   (Japan)

Author keywords

HMG1; HMG1 2 box; Model building; Mutagenesis; Protein DNA interaction

Indexed keywords

DNA BINDING PROTEIN; HIGH MOBILITY GROUP PROTEIN;

AMINO ACID SEQUENCE; ARTICLE; GENETIC CONSERVATION; MUTATION; PROTEIN DNA BINDING;

EID: 0033065073     PISSN: 0021924X     EISSN: None     Source Type: Journal    
DOI: 10.1093/oxfordjournals.jbchem.a022300     Document Type: Article

References (48)

1. Bustin, M., Lehn, D.A., and Landsman, D. (1990) Structural features of the HMG chromosomal proteins and their genes. Biochim. Biophys. Acta 1049, 231-243
2. Landsman, D. and Bustin, M. (1993) A signature for the HMG-1 box DNA binding proteins. BioEssays 15, 539-546
3. Bustin, M. and Reeves, R. (1996) High-mobility-group chromosomal proteins: architectural components that facilitate chromatin function. Prog. Nucleic Acid Res. Mol. Biol. 54, 35-100
4. Tsuda, K., Kikuchi, M., Mori, K., Waga, S., and Yoshida, M. (1988) Primary structure of non-histone protein HMG1 revealed by the nucleotide sequence. Biochemistry 27, 6159-6163
5. Aizawa, S., Nishino, H., Saito, K., Kimura, K., Shirakawa, H., and Yoshida, M. (1994) Stimulation of transcription in cultured cells by high mobility group protein 1: Essential role of the acidic carboxyl-terminal region. Biochemistry 33, 14690-14695
6. Ogawa, Y., Aizawa, S., Shirakawa, H., and Yoshida, M. (1995) Stimulation of transcription accompanying relaxation of chromatin structure in cells overexpressing high mobility group 1 protein. J. Biol. Chem. 270, 9272-9280
7. Jantzen, H.M., Admon, A., Bell, S.P., and Tjian, R. (1990) Nuclear transcription factor hUBF contains a DNA binding motif with homology to HMG proteins. Nature 344, 830-836
8. Sinclair, A.H., Berta, P., Palmer, M.S., Hawkins, J.R., Griffiths, B.L., Smith, M.J., Foster, J.W., Frischauf, A.M., Lovell-Badge, R., and Goodfellow, P.N. (1990) A gene from the human sex-determining region encodes a protein with homology to a conserved DNA binding motif. Nature 346, 240-244
9. Travis, A., Amsterdam, A., Belanger, C., and Grosschedl, R. (1991) LEF-1, a gene encoding a lymphoid-specific protein with an HMG domain, regulates T-cell receptor a-enhancer function. Genes Dev. 5, 880-894
10. Parisi, M.A. and Clayton, D.A. (1991) Similarity of human mitochondrial transcription factor 1 to high mobility group proteins. Science 252, 965-969
11. Ner, S.S. (1992) HMGs everywhere. Curr. Biol. 2, 208-210
12. Grosschedl, R., Giese, K., and Pagel, J. (1994) HMG domain proteins: architectural elements in the assembly of nucleoprotein structures. Trends Genet. 10, 94-100
13. van Houte, L.P., Chuprina, V.P., van der Wetering, M., Boelens, R., Kaptein, R., and Clevers, H. (1995) Solution structure of the sequence-specific HMG box of the lymphocyte transcriptional activator Sox-4. J. Biol. Chem. 270, 30516-30524
14. Werner, M.H., Huth, J.R., Gronenborn, A.M., and Clore, G.M. (1995) Molecular basis of human 46X, Y sex reversal revealed from the three-dimensional solution structure of the human SRY-DNA complex. Cell 81, 705-714
15. Love, J.J., Li, X., Case, D.A., Giese, K., Grosschedl, R., and Wright, P.E. (1995) Structural basis for DNA bending by the architectural transcription factor LEF-1. Nature 376, 791-795
16. Bidney, D.L. and Reeck, G.R. (1978) Purification from cultured hepatoma cells of two nonhistone chromatin proteins with preferential affinity for single-stranded DNA. Biochem. Biophys. Res. Commun. 85, 1211-1218
17. Isackson, P.J., Fishback, J.L., Bidney, D.L., and Reeck, G.R. (1979) Preferential affinity of high molecular weight high mobility group non-histone chromatin proteins for single-stranded DNA. J. Biol. Chem. 254, 5569-5572
18. Yoshida, M. and Shimura, K. (1984) Unwinding of DNA by nonhistone chromosomal protein HMG(1+2) from pig thymus as determined with endonuclease. J. Biochem. 95, 117-124
19. Hamada, H. and Bustin, M. (1985) Hierarchy of binding sites for chromosomal proteins HMG1 and 2 in supercoiled deoxyribonucleic acid. Biochemistry 24, 1428-1433
20. Bianchi, M.E., Beltrame, M., and Paonessa, G. (1989) Specific recognition of cruciform DNA by nuclear protein HMG1. Science 243, 1056-1059
21. Waga, S., Mizuno, S., and Yoshida, M. (1990) Chromosomal protein HMG1 removes the transcriptional block caused by the cruciform in supercoiled DNA. J. Biol. Chem. 265, 19424-19428
22. Waga, S., Mizuno, S., and Yoshida, M. (1988) Nonhistone protein HMG1 removes the transcriptional block caused by left-handed Z-form segment in a supercoiled DNA. Biochem. Biophys. Res. Commun. 153, 334-339
23. Pil, P.M. and Lippard, S.J. (1992) Specific binding of chromosomal protein HMG1 to DNA damaged by the anticancer drug cisplatin. Science 256, 234-237
24. 2+-dependent unwinding of DNA by nonhistone chromosomal protein HMG(1+2) from pig thymus as determined by DNA melting temperature analysis. J. Biochem. 95, 423-429
25. Sheflin, L.G. and Spaulding, S.W. (1989) High mobility group protein 1 preferentially conserves torsion in negatively super-coiled DNA. Biochemistry 28, 5658-5664
26. Paull, T.T., Haykinson, M.J., and Johnson, R.C. (1993) The nonspecific DNA binding and -bending proteins HMG1 and HMG2 promote the assembly of complex nucleoprotein structure. Genes Dev. 7, 1521-1534
27. Pil, P.M., Chow, C.S., and Lippard, S.J. (1993) High-mobility-group 1 protein mediates DNA bending as determined by ring closures. Proc. Natl. Acad. Sci USA 90, 9465-9469
28. Weir, H.M., Kraulis, P.J., Hill, C.S., Raine, A.R.C., Laue, E.D., and Thomas, J.O. (1993) Structure of the HMG box motif in the B-domain of HMG1. EMBO J. 12, 1311-1319
29. Read, C.M., Cary, P.D., Crane-Robinson, C., Driscoll, P.C., and Norman, D.G. (1993) Solution structure of a DNA binding domain from HMG1. Nucleic Acids Res. 21, 3427-3436
30. Hardman, C.H., Broadhurst, R.W., Raine, A.R., Grasser, K.D., Thomas, J.O., and Laue, E.D. (1995) Structure of the A-domain of HMG1 and its interaction with DNA as studied by heteronuclear three- and four-dimensional NMR spectroseopy. Biochemistry 34, 16596-16607
31. Studier, F.W. and Moffatt, B.A, (1986) Use of bacteriophage T7 RNA polymerase to direct selective high-level expression of cloned genes. J. Mol. Biol. 189, 113-130
32. Igarashi, K. and Iahihama, A. (1991) Bipartite functional map of the E. coli RNA polymerase alpha subunit: involvement of the C-terminal region in transcription activation by cAMP-CRP. Cell 65, 1015-1022
33. Schagger, H. and von Jagow, G. (1987) Tricine-sodium dodecyl sulfate-polyacrylamide gel electrophoresis for the separation of proteins in the range from 1 to 100kDa. Anal. Biochem. 166, 368-379
34. Bondeson, K., Frostell-Karlsson, A., Fägerstam, L., and Magnusson, G. (1993) Lactose represser-operator DNA interactions: Kinetic analysis by a surface plasmon resonance biosensor. Anal. Biochem. 214, 245-251
35. Fisher, R.J., Fivash, M., Casas-Finet, J., Erickson, J.W., Kondoh, A., Bladen, S.V., Fisher, C., Watson, D.K., and Papas, T. (1994) Real-time DNA binding measurements of the ETS1 recombinant oncoproteins reveal significant kinetic differences between the p42 and p51 isoform. Protein Sci. 3, 257-266
36. Parsons, I.D., Persson, B., Mekhalfia, A., Blackburn, G.M., and Stockley, P.G. (1995) Probing the molecular mechanism of action of co-repressor in the E. coli methionine represser-operator complex using surface plasmon resonance (SPR). Nucleic Acids Res. 23, 211-216
37. Bernstein, F.C., Koetzle, T.F., Williams, G.J., Meyer, E.F. Jr., Brice, M.D., Rodgers, J.E., Kennard, O., Shimanouchi, T., and Tasumi, M. (1977) The Protein Data Bank. A computer-based archival file for macromolecular structures. Eur. J. Biochem. 80, 319-324
38. Butler, A.P., Mardian, J.K.W., and Olins, D.E. (1985) Nonhistone chromosomal protein HMG1 interaction with DNA. J. Biol. Chem. 260, 10613-10620
39. Kohlstaedt, L.A. and Cole, R.D. (1994) Effect of pH on interactions between DNA and high-mobility group protein HMG1. Biochemistry 33, 12702-12707
40. Carlsson, P., Waterman, M.L., and Jones, K.A. (1993) The hLEF/TCF-1a HMG protein contains a context-dependent transcriptional activation domain that induces the TCRα enhancer in T cells. Genes Dev. 7, 2418-2430
41. Wagner, J.P., Quill, D.M., and Pettijohn, D.E. (1995) Increased DNA-bending activity and higher affinity DNA binding of high mobility group protein HMG-1 prepared without acids. J. Biol. Chem. 270, 7394-7398
42. Shirakawa, H., Tanigawa, T., Sugiyama, S., Kobayashi, M., Terashima, T., Yoshida, K., Arai, T., and Yoshida, M. (1997) Nuclear accumulation of HMG2 protein is mediated by basic regions interspaced with a long DNA-binding sequence, and retention within the nucleus requires the acidic carboxyl terminus. Biochemistry 36, 5992-5999
43. van Leeuven, H.C., Strating, M.J., Rensen, M., de Laat, W., and van del Vliet, P.C. (1997) Linker length and composition influence the flexibility of Oct-1 DNA binding. EMBO J. 16, 2043-2053
44. Schwabe, J.W.R. and Rhodes, D. (1997) Linkers made to measure. Nature Struct. Biol. 4, 680-683
45. Shirakawa, H., Tsuda, K., and Yoshida, M. (1990) Primary structure of non-histone chromosomal protein HMG2 revealed by the nucleotide sequence. Biochemistry 29, 4419-4423
46. Pentecost, B.T., Wright, J.M., and Dixon, G.H. (1985) Isolation and sequence of cDNA clones coding for a member of the family of high mobility group proteins (HMG-T) in trout and analysis of HMG-T-mRNA's in trout tissues. Nucleic Acids Res. 13, 4871-4888
47. Vaccari, T., Beltrame, M., Ferrari, S., and Bianchi, M.E. (1998) Hmg4, a new member of the Hmg1/2 gene family. Genomics 49, 247-252
48. Niemeyer, C.C., Foerster-Ziober, A., and Flytzanis, C.N. (1995) Purification of a high-mobility-group 1 sea-urchin protein and cloning of cDNAs. Gene 164, 211-218