Lack of effect of HPA axis hyperactivity on hormonal responses to d-fenfluramine in major depressed patients: Implications for pathogenesis of suicidal behaviour

Psychoneuroendocrinology

Volumn 26, Issue 5, 2001, Pages 521-537

  Duval, Fabrice ^a   Mokrani, Marie Claude ^b   Correa, Humberto ^c   Bailey, Paul ^b   Valdebenito, Marcelo ^b   Monreal, José ^a   Crocq, Marc Antoine ^a   Macher, Jean Paul ^a  

^a Centre Hospitalier de Rouffach   (France)

^b FORENAP   (France)

^c Institute of Biolological Sciences of the Federal University of Mina   (Brazil)

Author keywords

ACTH; Cortisol; d fenfluramine; DST; Major depression; Prolactin; Suicide

Indexed keywords

CORTICOSTEROID; CORTICOTROPIN; DEXAMETHASONE; DEXFENFLURAMINE; HYDROCORTISONE; PROLACTIN; SEROTONIN; SEROTONIN UPTAKE INHIBITOR;

ADULT; ARTICLE; BRAIN LEVEL; CONTROLLED STUDY; DEPRESSION; DEXAMETHASONE SUPPRESSION TEST; ENDOCRINE DISEASE; FEMALE; HORMONE ACTION; HORMONE RESPONSE; HUMAN; HYDROCORTISONE BLOOD LEVEL; HYPERACTIVITY; HYPOTHALAMUS HYPOPHYSIS ADRENAL SYSTEM; MAJOR CLINICAL STUDY; MALE; PATHOGENESIS; PRIORITY JOURNAL; SEROTONINERGIC SYSTEM; SUICIDAL BEHAVIOR;

ADRENAL GLANDS; ADRENOCORTICOTROPIC HORMONE; ADULT; DEPRESSION; DEXAMETHASONE; FEMALE; FENFLURAMINE; GLUCOCORTICOIDS; HUMANS; HYDROCORTISONE; HYPOTHALAMO-HYPOPHYSEAL SYSTEM; MALE; PROLACTIN; SEROTONIN; SEROTONIN AGENTS; SEROTONIN UPTAKE INHIBITORS; SUICIDE, ATTEMPTED;

EID: 0035042310     PISSN: 03064530     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0306-4530(01)00011-7     Document Type: Article

References (78)

1. Serotonergic function and negative and depressive symptomatology in Schizophrenia and major depression
2. Peripheral hormonal responses to D-fenfluramine as a probe of central serotonergic function in humans
3. 5-HIAA in the cerebrospinal fluid: A biochemical suicide predictor?
4. Studies of CSF-5-HIAA in depression and suicidal behavior
5. The dexamethasone suppression test: An overview of its current status in Psychiatry
6. Increase of tryptophan hydroxylase enzyme protein by dexamethasone in adrenalectomized rat midbrain
7. Adrenocortical function and suicidal behavior in depressive disorders
8. A specific laboratory test for the diagnosis of melancholia: Standardisation, validation, and clinical utility
9. Reduced prolactin and cortisol responses to d-fenfluramine in depressed compared to healthy matched control subjects
10. Does central serotonergic function correlate inversely with aggression? A study using D-fenfluramine in healthy subjects
11. Assessment of serotonergic function in major depression using d-fenfluramine: Relation to clinical variables and antidepressant response
12. Serotoninergic studies in patients with affective and personality disorders. Correlates with suicidal and impulsive aggressive behaviour
13. 5-HT2a/2c receptor blockade by amesergide fully attenuates prolactin response to d-fenfluramine challenge in physically healthy human subjects
14. 5-HT3 receptor antagonism by ondansetron does not attenuate prolactin response to D-fenfluramine challenge in healthy human subjects
15. Hormonal responses to D-and D,L-fenfluramine in healthy human subjects
16. Acute tryptophan depletion attenuates the prolactin response to d-fenfluramine challenge in healthy human subjects
17. Dexamethasone suppression of corticosteroid secretion: Evaluation of the site of action by receptor measures and functional studies
18. Serotonergic function and suicidal behavior in schizophrenia
19. Prolactin response to D-fenfluramine and suicidal behavior in depressed patients
20. Suicide and the dexamethasone suppression test in unipolar depression
21. Dexfenfluramine. An updated review of its therapeutic use in the management of obesity
22. Glucocorticoids and the genesis of depressive ilness: A psychobiological model
23. The influence of cortisol on spontaneous and 5-HT stimulated prolactin release in man
24. Thyroid axis activity and serotonin function in major depressive episode
25. Decreased 5-HT1A and increased 5-HT2A receptor binding after chronic corticosterone associated with a behavioural indication of depression but not anxiety
26. From fenfluramine racemate to d-fenfluramine. Specificity and potency of the effects on the serotonergic system and food intake
27. Ritanserin attenuates anorectic endocrine and thermic responses to d-fenfluramine in human volunteers
28. Oral D-fenfluramine and neuroendocrine challenge: Problems with the 30 mg dose in men
29. A rating scale for depression
30. Neuropeptides and the hypothalamic-pituitary-adrenocortical (HPA) system: Review of recent research strategies in depression
31. Multiple hormone responses to stimulation with D,L-fenfluramine in patients with major depression before and after antidepressive treatment
32. Pathophysiology of HPA axis abnormalities in patients with major depression: An update
33. Prolactin response to D-fenfluramine in outpatients with major depression
34. Effect of ACTH, adrenalectomy and the combination treatment on the density of 5-HT2 receptor binding sites in neocortex of rat forebrain and 5-HT2 receptor-mediated wet-dog shake behaviors
35. Selective control by corticosterone of serotonin1 receptor capacity in raphe-hippocampal system
36. Effects of the menstrual cycle on dependent variables in mood disorder research
37. The effects of serotonin3 receptor blockade on the psychobiological response to intravenous clomipramine in healthy human subjects
38. Corticotropin and cortisol secretion after central 5-HT1A receptor activation: Effect of 5-HT receptor and beta-adrenoreceptor antagonists
39. Serotonergic stimulation of adrenocorticotropin secretion in man
40. The fenfluramine challenge test in the affective spectrum: A possible marker of endogeneity and severity
41. Hypothalamic-pituitary-adrenal and -thyroid axis dysfunctions and decrements in the availability of L-tryptophan as biological markers of suicidal ideation in major depressed females
42. HPA-axis hormones and prolactin responses to dextro-fenfluramine in depressed patients and healthy controls
43. The serotonin hypothesis of major depression
44. The neurobiology of suicide
45. Dexamethasone suppresssion test status and severity of depression
46. Elevated basal trough levels of corticosterone suppress hippocampal 5-hydroxytryptamine(1A) receptor expression in adrenally intact rats: Implication for the pathogenesis of depression
47. Corticosterone and serotonergic neurotransmission in the hipocampus: Functional implications of central corticosteroid receptor diversity
48. Effect of pindolol pretreatment on MK212-induced plasma cortisol and prolactin responses in normal men
49. Basic principles of ROC analysis
50. Hormonal responses to fenfluramine in depressed and control subjects
51. Dexamethasone suppression test (DST) in relation to depressive somatic and suicidal manifestations
52. Multihormonal responses to apomorphine in mental illness
53. HPA dysfunction in depression: Correlation with monoamine system abnormalities
54. DST studies in psychotic depression: A meta-analysis
55. The dexamethasone suppression test and completed suicide
56. Prolactin and cortisol responses to d-fenfluramine in major depression: Evidence for diminished responsivity of central serotoninergic function
57. Evidence for 5-hydroxytryptamine 1A receptor involvment in the control of prolactin secretion in man
58. Effect of pindolol on the prolactin response to d-fenfluramine
59. 5-HT neuroendocrine function in major depression: Prolactin and cortisol responses to d-fenfluramine
60. Suicidal behavior and hypothalamic-pituitary-adrenocortical axis in child psychiatric inpatients
61. The dexamethasone suppression test in violent suicide attempters with major depression
62. Hypothalamic-pituitary-adrenal axis function and platelet serotonin concentrations in depressed patients
63. Efects of antiglucocorticoid treatment on 5-HT1A function in depressed patients and healthy subjects
64. Oral d-fenfluramine test in treatment-refractory depression. Plasma prolactin response compared in patients with and without suicide attempts and in a healthy reference group
65. Depressive symptoms and suicidal behavior in adolescents
66. Hypothalamic-pituitary-adrenal axis function and suicidal behavior in depression
67. The dexamethasone suppression test and suicide attempts
68. 5-Hydroxytryptamine in the hind-brain of depressive suicides
69. Neuroendocrine markers of serotonin responsivity in depression
70. Tritiated imipramine binding sites are decreased in the frontal cortex of suicides
71. The dexamethasone supression test in suicidal patients with unipolar depression
72. Cortisol synthesis inhibition: A new treatment strategy for the clinical and endocrine manifestations of depression
73. Pharmacological studies on the serotonergic and nonserotonin-mediated stimulation of prolactin and corticosterone secretion by fenfluramine. Effects of pretreatment with fluoxetine, indalpine, PCPA, and L-tryptophan
74. Cortisol response to a combined dexamethasoe-human corticotrophin-releasing hormone chalenge in patients with depression
75. Lack of effect of hydrocortisone treatment on d-fenfluramine-mediated prolactin release
76. Increased evening activation of the hypothalamic-pituitary-adrenal axis in depressed patients