Clinical implications of physiological changes in the aging heart

Drugs and Aging

Volumn 18, Issue 4, 2001, Pages 263-276

  Pugh, K Gregory ^a,b,c   Wei, Jeanne Y ^a,b  

^a BETH ISRAEL DEACONESS MEDICAL CENTER   (United States)

^b HARVARD MEDICAL SCHOOL   (United States)

^c Naval School of Health Sciences   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ADENOSINE TRIPHOSPHATASE (CALCIUM); BETA ADRENERGIC RECEPTOR BLOCKING AGENT; CALCIUM CHANNEL BLOCKING AGENT; CATECHOLAMINE DERIVATIVE; DIGITALIS; DIGOXIN; DIPEPTIDYL CARBOXYPEPTIDASE INHIBITOR; DIURETIC AGENT;

AGING; ARTERY COMPLIANCE; ATHEROSCLEROSIS; CALCIFICATION; CARDIOVASCULAR FUNCTION; HEART ARRHYTHMIA; HEART CONDUCTION; HEART LEFT VENTRICLE HYPERTROPHY; HEART MUSCLE FIBROSIS; HEART OUTPUT; HEART RATE; LIFESTYLE; ORTHOSTATIC HYPOTENSION; PRESSORECEPTOR REFLEX; PRIORITY JOURNAL; REVIEW; SYSTOLIC HYPERTENSION;

EID: 0035038988     PISSN: 1170229X     EISSN: None     Source Type: Journal    
DOI: 10.2165/00002512-200118040-00004     Document Type: Review

References (76)

1. Demographics and cardiology, 1950-2050
2. Research Recommendations for cardiovascular aging research. NIA Cardiovacular Aging Advisory Panel
3. The challenges of health care delivery to the elderly patient with cardiovascular disease: Demographic, epidemiologic, fiscal, and health policy implications
4. In defense of a department of geriatrics
5. Cardiovascular aging research: The next horizons
6. Exercise-induced silent myocardial ischemia in master athletes
7. Cardiomyopathy of the aging human heart: Myocyte loss and reactive cellular hypertrophy
8. Age and the cardiovascular system
9. Recent advances in cardiac hypertrophy
10. The role of gender, the menopause and hormone replacement on cardiovascular function
11. The sigmoid septum: Variation in the contour of the left ventricular outlet
12. An echocardiographic study of localized subaortic hypertrophy
13. Age-associated changes in left ventricular outflow tract geometry in normal subjects
14. Stress-induced left ventricular outflow tract obstruction: A potential cause of dyspnea in the elderly
15. The clinical impact of dynamic intraventricular obstruction during dobutamine stress echocardiography
16. Age and the cardiovascular system
17. Pathology of the senescent heart: Anatomic observations on 237 autopsy studies of patients 90 to 105 years old
18. Ageing of the heart
19. Cardiovascular regulatory mechanisms in advanced age
20. Comparison of cardiac findings at necropsy in octogenarians, nonagenerains, centenarians
21. Cardiovascular consequences of the aging process
22. Systolic blood pressure revisited
23. Pulse pressure not mean pressure determines cardiovascular risk in older hypertensive patients
24. Arterial stiffness
25. Hormonal therapy increases arterial compliance in postmenopausal women
26. Disparate effects of antihypertensive drugs on large artery distensibility and compliance in hypertension
27. Improved arterial distensibility in normotensive subjects on a low salt diet
28. Dehydration: Evaluation and management in older adults. Council on scientific affairs, american medical association
29. Aging of the vascular-wall and atherosclerosis
30. Age-related changes in vascular responses: A review
31. Age-related endothelial dysfunction with respect to nitric oxide, endothelium-derived hyperpolarizing factor and cyclooxygenase products
32. Lipoprotein modification and atherosclerosis in aging
33. Markers of inflammation as predictors in cardiovascular disease
34. Predictors of congestive heart failure in the elderly: The Cardiovascular Health Study
35. Neutrophilia and congestive heart failure after acute myocardial infarction
36. Resting and active mechanical properties of trabeculae carnae from aged male rats
37. 2+-ATPases in the cardiovascular system during growth and proliferation
38. Interaction of hypoxia and aging in the heart: Analysis of high energy phosphate content
39. Diastolic heart failure
40. Differences in cardiovascular responses to isoproterenol in relation to age and exercise training in healthy men
41. Effects of age and gender on cardiovascular responses to isoproterenol
42. Age-dependent changes in cardiac muscarinic receptor function in healthy volunteers
43. Orthostatic hypotension in the elderly
44. Postural dysregulation in systolic blood pressure in associated with worsened scoring on neurobehavioral function tests and leukoariosis in the older elderly living in a community
45. Postprandial hypotension: Epidemiology, pathophysiology, and clinical management
46. Endothelial function in health and disease: New insights into the genesis of cardiovascular disease
47. Aging is associated with endothelial dysfunction in the human forearm vasculature
48. Endothelial dysfunction: A reversible clinical measure of atherogenic susceptibility and cardiovascular inefficiency
49. Vitamin C improves age-related endothelial dysfunction in humans
50. Vitamin E ingestion does not improve arterial endothelial dysfunction in older adults
51. Autoimmunity and atherosclerosis
52. Role of reactive oxygen species in cardiovascular aging
53. Vitamin E and heart disease: Basic science to clinical intervention trials
54. Seminars in medicine of the Beth Israel Deaconess Medical Center: Caloric intake and aging
55. Heart failure and the aging myocardium: Possible role of cardiac mitochondria
56. Biomolecular changes in the aging myocardium: The effect of enalapril
57. AGEs and their interaction with AGE-receptors in vascular disease and diabetes mellitus. I. The AGE concept
58. Aminoguanidine prevents age-related arterial stiffening and cardiac hypertrophy
59. Death by design: Programmed cell death in cardiovascular biology and disease
60. Apoptotic cell death in heart failure
61. 2+-ATPase
62. Masters athletes: Factors affecting performance
63. Exercise and older patients: Guidelines for the clinician
64. Continium of cardiovascular performance across a broad range of fitness levels in healthy older men
65. Enhanced left ventricular diastolic filling associated with long-term endurance training
66. Chronic exercise training protects aged cardiac muscle against hypoxia
67. Vascular compliance as a measure of biological age
68. Increased pulse pressure and risk of heart failure in the elderly
69. Effects of age and aerobic capacity on arterial stiffness in healthy adults
70. Exercise training increases total systemic arterial compliance in humans
71. Diuretic-induced hyponatremia
72. Left ventricular remodelling and dysfunction: Can the process be prevented?
73. Aldosterone and the heart: Towards a physiological function?
74. The effect of spironolactone on morbidity and mortality in patients with severe heart failure. Randomized Aldactone Evaluation Study investigators
75. NO and cardiac diastolic function