Ageing of the heart

British Journal of Biomedical Science

Volumn 55, Issue 2, 1998, Pages 136-148

  Roffe, Christine ^a  

^a UNIVERSITY HOSPITAL OF NORTH STAFFORDSHIRE   (United Kingdom)

Author keywords

Ageing; Heart; Myocardial diseases

Indexed keywords

CALCIUM; LIPOFUSCIN;

AGING; CALCIUM TRANSPORT; CAPILLARY DENSITY; EPICARDIUM; HEART; HEART MUSCLE FIBROSIS; HUMAN; HYPERTENSION; ISCHEMIC HEART DISEASE; LIPID STORAGE; PREVALENCE; PRIORITY JOURNAL; REVIEW;

ADULT; AGED; AGED, 80 AND OVER; AGING; DIASTOLE; HEART; HUMANS; MIDDLE AGED; MYOCARDIUM;

EID: 0031848412     PISSN: 09674845     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Review

References (29)

1. Rodeheffer RJ, Gerstenblith G, Becker IC, Fleg JL, Weisfeldt ML, Lakatta LG. Exercise cardiac output is maintained with advancing age in healthy human subjects: Cardiac dilatation and increased stroke volume compensate for diminished heart rate. Circulation 1984: 69:203-13.
2. Roberts WC. Morphological features of the elderly heart. In: Tresh DD, Aronow WS, eds. Cardiovascular disease in the elderly patient. New York: Marcel Dekker, 1993.
3. Anversa P, Palackal T, Sonnenblick EH, Olivetti G, Meggs LG. Myocyte cell loss and myocyte cellular hyperplasia in the hypertrophied ageing rat heart. Circ Res 1990; 67:871-85.
4. Hossack KF, Bruce RA. Maximal cardiac function in sedentary normal men and women. Comparison of age-related changes. J Appl Physiol 1982; 53:799-804.
5. Higginbottam MB, Morris KG, Williams RS, Coleman RE, Cobb FR. Physiologic basis for the age-related decline in aerobic work capacity. Am J Cardiol 1986; 57:1374-9.
6. Weisfeldt ML, Loeven WA, Shock NW. Resting and active mechanical properties of trabeculae caraenae from aged male rats. Am J Physiol 1971; 220:921-1927.
7. Lakatta EG, Gerstenblith G, Agnell CS, Shock NW, Weisfeldt ML. Prolonged contraction duration in aged myocardium. J Clin Invest 1975; 55:61-8.
8. Xiao RP, Lakatta E. Mechanisms of altered beta-adrenergic modulation of the cardiovascular system with aging. Rev Biol Gerontol 1991; 1:309-22.
9. Sohal RS, Agarwal S, Sohal BH. Oxidative stress and aging in the Mongolian gerbil (Meriones unguiculatus). Mech Ageing Dev 1995; 81:15-25.
10. Ji LL, Dillon D, Wu E. Myocardial aging: antioxidant enzyme systems and related biochemical properties. Am J Physiol 1991; 30:R386-92.
11. Hazelton GA, Lang CA. Glutathione contents of tissues in the aging mouse. Biochem J 1980; 188:25-30.
12. Ji LL. Antioxidant response to exercise and ageing. Med Sci Sports Exercise 1993; 25:225-31.
13. Martin GM. Biological mechanisms of ageing. In: Evans GJ, Williams JF, eds. Oxford textbook of geriatric medicine. Oxford: Oxford Medical Publications, 1992.
14. Sakata N, Meng J, Jimi S, Segawa M, Takebayashi S. Aging of the aorta and atherosclerosis. Role of non-enzymatic glycation of collagen. Jap J Geriatr 1995; 32:336-43.
15. Xiao RP, Lakatta E. Mechanisms of altered bcta-adrenergic modulation of the cardiovascular system with aging. Rev Biol Gerontol 1991; 1:309-22.
16. Guarnieri T, Filburn CR, Zitnik G, Roth GS, Lakatta EG. Contractile and biochemical correlates of beta-adrenergic stimulation of the aged heart. Am J Physiol 1980; 239:H501-8.
17. Cerbai E, Guerra L, Varani K, Barbieri M, Borea PA, Mugelli A. Beta-adrenoceptor subtypes in young and old rat ventricular myocytes: a combined patch-clamp and binding study. Br J Pharmacol 1995; 116:1835-42.
18. Scarpace PJ, Baresi LA. Increased beta-adrenergic agonist receptors in the light-density membrane fraction in lungs from senescent rat. J Gerontol 1988; 43:B163-7.
19. Brodde OE, Zerkowski HR, Schranz D et al. Age-dependent changes in the beta-adrenoceptor-G-protein(s)-adenyl cyclase system in human right atrium. J Cardiovasc Pharmacol 1995; 26:20-6.
20. Boehm M, Dorner H, Htun P, Lensche H, Platt D, Erdmann E. Effects of exercise on myocardial adenylate cyclase and Gialpha expression in senescence. Am J Physiol 1993; 264:H805-14.
21. Tobise K, Ishikawa Y, Holmer SR et al. Changes in type VI adenyl cyclase isoform expression correlate with a decreased capacity for cAMP generation in the aging ventricle. Circ Res 1994; 74:596-603.
22. Fleg JL, Tzankoff SP, Lakatta EG. Age-related augmentation of plasma catecholamines during dynamic exercise in healthy males. J Appl Physiol 1985; 59:1033-9.
23. Esler M, Skews H, Leonard P, Jackman G, Bobik A, Korner P. Age dependence of noradrenaline kinetics in relation to age and blood pressure in man. Clin Sci 1981; 60:217-19.
24. Gardin JM, Siscovick D, Anton-Culver H et al. Sex, age and disease affect echocardiographic left ventricular mass and systolic function in the free-living elderly. Circulation 1995; 91:1739-48.
25. Kannel WB. Left ventricular hypertrophy as a risk factor: the Framingham experience. J Hypertens 1991; 9(suppl.2):S3-9.
26. Weber KT, Brilla CG, Janicki JS. Myocardial fibrosis: functional significance and regulatory factors. Cardiorasc Res 1993; 27:341-8.
27. Anversa P, Capasso JM, Ricci R, Sonnenblick EH, Olivetti G. Morphometric analysis of coronary capillaries during physiologic myocardial growth and induced cardiac hypertrophy: a review. Int J Microcirc Clin Exp 1989; 8:353-63.
28. Fairweather DS. Aging of the heart and the cardiovascular system. Rev Clin Geront 1992; 2:83-103.
29. Brocklehurst JC, Tallis RC, Fillit AM, eds. Textbook of geriatric medicine and gerontology. London: Churchill Livingstone, 1992.