PKC-mediated stimulation of amphibian CFTR depends on a single phosphorylation consensus site. Insertion of this site confers PKC sensitivity to human CFTR

Journal of General Physiology

Volumn 117, Issue 5, 2001, Pages 457-467

  Button, Brian ^a   Reuss, Luis ^a   Altenberg, Guillermo A ^a  

^a UNIVERSITY OF TEXAS MEDICAL BRANCH   (United States)

Author keywords

ABC proteins; Chloride channel; PKA; R domain

Indexed keywords

CHLORIDE; CHLORIDE CHANNEL; CYCLIC AMP DEPENDENT PROTEIN KINASE; PROTEIN KINASE; TRANSMEMBRANE CONDUCTANCE REGULATOR;

ARTICLE; CYSTIC FIBROSIS; GENE INSERTION; GENE MUTATION; MUTAGENESIS; NECTURUS; NONHUMAN; PHOSPHORYLATION; PROTEIN DOMAIN; XENOPUS LAEVIS;

AMINO ACID SEQUENCE; ANIMALS; BINDING SITES; CONSENSUS SEQUENCE; CYCLIC AMP; CYCLIC AMP-DEPENDENT PROTEIN KINASES; CYSTIC FIBROSIS TRANSMEMBRANE CONDUCTANCE REGULATOR; HUMANS; ION CHANNEL GATING; MOLECULAR SEQUENCE DATA; MUTAGENESIS, SITE-DIRECTED; NECTURUS MACULOSUS; OOCYTES; PATCH-CLAMP TECHNIQUES; PHOSPHORYLATION; PROTEIN KINASE C; PROTEIN STRUCTURE, TERTIARY; SPECIES SPECIFICITY; THREONINE; XENOPUS LAEVIS;

EID: 0035034208     PISSN: 00221295     EISSN: None     Source Type: Journal    
DOI: 10.1085/jgp.117.5.457     Document Type: Article

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