The new antirheumatic drug KE-298 suppresses monocyte chemoattractant protein (MCP)-1 and RANTES production in rats with adjuvant-induced arthritis and in IL-1β-stimulated synoviocytes of patients with rheumatoid arthritis

Rheumatology International

Volumn 20, Issue 4, 2001, Pages 149-153

  Inoue, Tomoyuki ^a,b   Yamashita, Miyuki ^a   Higaki, Megumu ^a  

^a ST MARIANNA UNIVERSITY SCHOOL OF MEDICINE   (Japan)

^b TAISHO PHARMACEUTICAL CO LTD   (Japan)

Author keywords

Adjuvant induced arthritis; MCP 1; RA synovtocytes; RANTES; Transcription factors

Indexed keywords

ANTIRHEUMATIC AGENT; ESONARIMOD; INTERLEUKIN 1; MONOCYTE CHEMOTACTIC PROTEIN 1; RANTES; TRANSCRIPTION FACTOR;

ADJUVANT ARTHRITIS; ADULT; AGED; ARTICLE; CLINICAL ARTICLE; CONTROLLED STUDY; DRUG EFFECT; DRUG EFFICACY; FEMALE; HUMAN; HUMAN TISSUE; MALE; NONHUMAN; PRIORITY JOURNAL; PROTEIN SECRETION; RAT; RHEUMATOID ARTHRITIS; SYNOVIOCYTE; T LYMPHOCYTE;

AGED; ANIMALS; ANTIRHEUMATIC AGENTS; ARTHRITIS, RHEUMATOID; BASE SEQUENCE; CELLS, CULTURED; CHEMOKINE CCL2; DISEASE MODELS, ANIMAL; ELECTROPHORESIS; FEMALE; HUMANS; INTERLEUKIN-1; MALE; MIDDLE AGED; MOLECULAR SEQUENCE DATA; PHENYLPROPIONATES; RANTES; RATS; RATS, SPRAGUE-DAWLEY; SENSITIVITY AND SPECIFICITY; SYNOVIAL MEMBRANE;

EID: 0035033284     PISSN: 01728172     EISSN: None     Source Type: Journal    
DOI: 10.1007/s002960100104     Document Type: Article

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