Preparation and antirheumatic activity of optically active 2-acetylthiomethyl-4-(4-methylphenyl)-4-oxobutanoic acid (KE-298)

Chemical and Pharmaceutical Bulletin

Volumn 44, Issue 3, 1996, Pages 602-604

  Kameo, Kazuya ^a   Takeshita, Kimiyo ^a   Yasuda, Yoshiko ^a   Matsumoto, Keita ^a   Tomisawa, Kazuyuki ^a  

^a TAISHO PHARMACEUTICAL CO LTD   (Japan)

Author keywords

2 acetylthiomethyl 4 (4 methylphenyl) 4 oxobutanonic acid; Absolute stereochemistry; Antirheumatic activity; Optical resolution

Indexed keywords

ESONARIMOD;

ADJUVANT DISEASE; ANIMAL EXPERIMENT; ARTICLE; DRUG EFFECT; DRUG STRUCTURE; NONHUMAN; POLARIMETRY; RAT; RHEUMATIC DISEASE; STEREOCHEMISTRY;

ANIMALS; ANTIRHEUMATIC AGENTS; ARTHRITIS, EXPERIMENTAL; CRYSTALLOGRAPHY, X-RAY; EDEMA; FEMALE; INTERLEUKIN-1; LIPOPOLYSACCHARIDES; LYMPHOCYTE ACTIVATION; MICE; MICE, INBRED C3H; OPTICAL ROTATION; PHENYLPROPIONATES; RATS; RECEPTORS, INTERLEUKIN-1; SPECTROPHOTOMETRY, INFRARED; STEREOISOMERISM; T-LYMPHOCYTES;

EID: 0029884963     PISSN: 00092363     EISSN: None     Source Type: Journal    
DOI: 10.1248/cpb.44.602     Document Type: Article

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