Identification of primitive hematopoietic progenitor cells in the rhesus macaque

Journal of Medical Primatology

Volumn 30, Issue 1, 2001, Pages 36-45

  Rosenzweig, Michael ^a,b   Marks, Douglas F ^a,b   DeMaria, Mary Ann ^a,b   Connole, Michelle ^a,b   Johnson, R Paul ^a,b  

^a HARVARD MEDICAL SCHOOL   (United States)

^b MASSACHUSETTS GENERAL HOSPITAL   (United States)

Author keywords

Bone marrow cells; Hematopoietic progenitors; Rhesus macaque

Indexed keywords

CD34 ANTIGEN; CD38 ANTIGEN; CD59 ANTIGEN; CELL MARKER; HLA DR ANTIGEN; THY 1 ANTIGEN;

ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; BONE MARROW TRANSPLANTATION; CELL CULTURE; CELL FRACTIONATION; CELL LINEAGE; CELL SUBPOPULATION; CONTROLLED STUDY; DILUTION; FLOW CYTOMETRY; GENE THERAPY; HEMATOPOIETIC STEM CELL; HUMAN; NONHUMAN; PARAMETER; PHYLOGENY; PRIORITY JOURNAL; RHESUS MONKEY;

ANIMALS; ANTIBODIES, MONOCLONAL; ANTIGENS, CD34; BONE MARROW; DISEASE MODELS, ANIMAL; FLOW CYTOMETRY; HEMATOPOIETIC STEM CELLS; HUMANS; MACACA MULATTA; THYMUS GLAND;

EID: 0035029171     PISSN: 00472565     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1600-0684.2001.300105.x     Document Type: Article

References (50)

1. In vivo synergy between recombinant human stem cell factor and recombinant human granulocyte colony-stimulating factor in baboons enhanced circulation of progenitor cells
2. Phenotypic and functional analysis of T-cell precursors in the human fetal liver and thymus: CD7 expression in the early stages of T- and myeloid-cell development
3. Isolation of a candidate human hematopoietic stem-cell population
4. + bone marrow cells
5. Gene therapy and immune restoration for HIV disease
6. + cells
7. Species specificity of human interleukin-3 demonstrated by cloning and expression of the homologous rhesus monkey (Macaca mulatta) gene
8. Expression of Thy-1 on human hematopoietic progenitor cells
9. Human fetal bone marrow early progenitors for T, B, and myeloid cells are found exclusively in the population expressing high levels of CD34
10. Demonstration of burst-promoting activity of recombinant human GM-CSF on circulating erythroid progenitors using an assay involving the delayed addition of erythropoietin
11. + cells in Thy-1 expression and cell cycle status in nonhuman primates mobilized or not mobilized with granulocyte colony-stimulating factor and/or stem cell factor
12. Stimulation of haematopoiesis in primates by continuous infusion of recombinant human GM-CSF
13. The evaluation of limiting dilution assays
14. The composition of CD34 subpopulations differs between bone marrow, blood and cord blood
15. + progenitor cells [published erratum appears in Exp Hematol 26:1272, 1998]
16. Isolation and functional properties of murine hematopoietic stem cells that are replicating in vivo
17. Dye efflux studies suggest the existence of CD34-negative/low hematopoietic stem cells in multiple species
18. lo marrow cells
19. Extended long-term culture reveals a highly quiescent and primitive human hematopoietic progenitor population
20. - cells in cord blood and bone marrow
21. + bone marrow cells highly enriched for pluripotent stem cells
22. - hematopoietic stem cells
23. Characterization of a monoclonal antibody (6G12) recognizing the cynomolgus monkey CD3 antigen
24. + human marrow cells that express low levels of Kit protein and enriched for long-term marrow-engrafting cells
25. Gene transfer into marrow repopulating cells: Comparison between amphotropic and gibbon ape leukemia virus pseudotyped retroviral vectors in a competitive repopulation assay in baboons
26. dim) and lymphoid subsets, and possible predictors of engraftment disease
27. Limiting dilution analysis of cells of the immune system
28. Thy-1 expression is linked to functional properties of primitive hematopoietic progenitor cells from human umbilical cord blood
29. - subpopulation from mobilized peripheral blood
30. -/lo fetal and adult bone marrow cells
31. Self-renewal of primitive human hematopoietic cells (long-term culture-initiating cells) in vitro and their expansion in defined medium
32. Use of human leukocyte-specific monoclonal antibodies for clinically immunophenotyping lymphocytes of rhesus monkeys
33. Efficient and durable gene marking of hematopoietic progenitor cells in nonhuman primates after nonablative conditioning
34. + hematopoietic progenitor cells with a hairpin ribozyme protects T cells and macrophages from simian immunodeficiency virus infection
35. + progenitor cells
36. + bone marrow cells
37. Purification and characterization of mouse hematopoietic stem cells
38. Long-term culture of human myeloid cells
39. - stem cells in fetal sheep
40. Characterization and partial purification of human marrow cells capable of initiating long-term hematopoiesis in vitro
41. Functional characterization of individual human hematopoietic stem cells cultured at limiting dilution on supportive marrow stromal layers
42. Assessment of hematopoietic cell differentiation by multi-dimensional flow cytometry
43. - progenitor cells
44. Flow cytometric assessment of human T-cell differentiation in thymus and bone marrow
45. Ex vivo expansion of genetically marked rhesus peripheral blood progenitor cells results in diminished long-term repopulating ability
46. + human hematopoietic progenitor cells
47. Gene transfer into hematopoietic stem cells of nonhuman primates
48. + lymphocyte depletion and viral replication in primary SIV infection
49. The "common stem cell" hypothesis reevaluated: Human fetal bone marrow contains separate populations of hematopoietic and stromal progenitors
50. The use of SIV-infected rhesus monkeys for the preclinical evaluation of AIDS drugs and vaccines