Cardiac cellular actions of hydrochlorothiazide

Fundamental and Clinical Pharmacology

Volumn 15, Issue 1, 2001, Pages 9-17

  Galán, Loipa ^a   Ferrer, Tania ^a   Artiles, Adriana ^a   Talavera, Karel ^a   Salinas, Eduardo ^b   Orta, Gerardo ^b   García Barreto, David ^a   Alvarez, Julio L ^a  

^a INSTITUTO DE CARDIOLOGÍA Y CIRUGÍA CARDIOVASCULAR   (Cuba)

^b BENEMÉRITA UNIVERSIDAD AUTÓNOMA DE PUEBLA   (Mexico)

Author keywords

Calcium channels; Diuretics; Heart; Hydrochlorothiazide; Patch clamp; Potassium channels

Indexed keywords

CALCIUM ION; CYCLIC AMP; HYDROCHLOROTHIAZIDE; ISOPRENALINE; POTASSIUM CHLORIDE; SODIUM ION;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; BLOOD PRESSURE REGULATION; CALCIUM TRANSPORT; CONTROLLED STUDY; DIURESIS; DRUG MECHANISM; HEART DEPOLARIZATION; HEART MUSCLE CELL; HEART MUSCLE POTENTIAL; INOTROPISM; INTRACELLULAR TRANSPORT; MOUSE; NONHUMAN; PRIORITY JOURNAL; VASCULAR RESISTANCE;

ACTION POTENTIALS; ANIMALS; CALCIUM; DIURETICS; DOSE-RESPONSE RELATIONSHIP, DRUG; ELECTROPHYSIOLOGY; HEART; HEART CONDUCTION SYSTEM; HEART VENTRICLES; HYDROCHLOROTHIAZIDE; MEMBRANE POTENTIALS; MUSCLE, SMOOTH; MYOCARDIAL CONTRACTION; MYOCARDIUM; PATCH-CLAMP TECHNIQUES; POTASSIUM CHANNELS; RATS; SODIUM; SODIUM CHLORIDE SYMPORTER INHIBITORS; STIMULATION, CHEMICAL;

EID: 0035028754     PISSN: 07673981     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1472-8206.2001.00009.x     Document Type: Article

References (30)

1. Diuretics
2. The mechanism of action of chlorothiazide
3. Diuretic complications
4. Hemodynamic changes during long term thiazide treatment of essential hypertension in responders and non-responders
5. Mechanism of antihypertensive action of prolonged administration of hydrochlorothiazide in rabbit and dog
6. Mironneau Ch Compared effects of indapamide, hydrochlorothiazide and chlorthalidone on electrical and mechanical activities in vascular smooth muscle
7. Direct vascular actions of hydrochlorothiazide and indapamide in isolated small vessels
8. Ion channel involvement in the acute vascular effects of thiazide diuretics and related compounds
9. Vasorelaxant actions of 5-OH-indapamide, a major metabolite of indapamide: Comparison with indapamide, hydrochlorothiazide and cicletanine
10. Potassium channel opening properties of thiazide diuretics in isolated mesenteric arteries
11. i by hydrochlorothiazide in guinea-pig isolated mesenteric arteries
12. Hydrochlorothiazide exerts no direct vasoactivity in the human forearm
13. Inhibition of carbonic anhydrase accounts for the direct vascular effects of hydrochlorothiazide
14. Thiazide-induced vasodilation in humans is mediated by potassium channel activation
15. Demonstration of a in vitro direct vascular relaxant effect of diuretics in the presence of plasma
16. What is the plasma cofactor required for direct vascular relaxant effect in vitro?
17. Action of indapamide on excitation contraction coupling in vascular smooth muscle
18. Indapamide-induced inhibition of calcium movement in smooth muscles
19. Distinct calcium channel isoforms mediate parathyroid hormone and chlorothiazide-stimulated calcium entry in transporting epithelial cells
20. Cellular calcium transport in renal epithelia: Measurement, mechanisms and regulation
21. Mechanism of calcium transport stimulated by chlorothiazide in mouse distal convoluted tubule cells
22. Block of Iks, the slow component of the delayed rectifier K current, by the diuretic indapamide in guinea pig myocytes
23. Effects of the diuretic agent indapamide on Na, transient outward and delayed rectifier currents in canine atrial myocytes
24. The efficacy and safety of diuretics in treating hypertension
25. Hypokalemia, hypomagnesemia and ventricular arrhythmia during diuretic treatment of arterial hypertension
26. Changes in electrical and mechanical activities of rabbit papillary muscle during hypoxic perfusion
27. 2+-channel blockade by oxodipine and elgodipine in rat cardiomyocytes
28. Improved patch-clamp techniques for high-resolution current recording from cells and cell-free membrane patches
29. Comparative bioavailability and pharmacokinetics of hydrochlorothiazide from oral tablet dosage forms determined by plasma level and urinary excretion methods
30. Arrhythmia control by prolonging repolarization: The concept and its potential therapeutic impact