Demonstration of an in vitro direct vascular relaxant effect of diuretics in the presence of plasma

Journal of Hypertension

Volumn 14, Issue 3, 1996, Pages 381-388

  Abrahams, Zuheir ^a   Tan, Lisa L Y ^a   Pang, Monica Y M ^a   Abrahams, Bethina ^a   Tan, Melissa M ^a   Wright, James M ^a  

^a UNIVERSITY OF BRITISH COLUMBIA   (Canada)

Author keywords

Chlorthalidone; Furosemide; Hydrochlorothiazide; Indapamide; Plasma; Rat vascular smooth muscle

Indexed keywords

CHLORTALIDONE; DIURETIC AGENT; FUROSEMIDE; HYDROCHLOROTHIAZIDE; INDAPAMIDE; LOOP DIURETIC AGENT; THIAZIDE DIURETIC AGENT;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIHYPERTENSIVE ACTIVITY; ARTICLE; MALE; NONHUMAN; PORTAL VEIN; PRIORITY JOURNAL; PULMONARY ARTERY; RAT; SMOOTH MUSCLE RELAXATION; VASCULAR ENDOTHELIUM; VASCULAR SMOOTH MUSCLE;

EID: 0029871424     PISSN: 02636352     EISSN: None     Source Type: Journal    
DOI: 10.1097/00004872-199603000-00016     Document Type: Article

References (51)

1. Collins R, Peto R, Macmahon S, Hebert P, Fiebach NH, Eberlein KA, et al.: Blood pressure, stroke, and coronary heart disease. 2. Short-term reductions in blood pressure: overview of randomised drug trials in their epidemiological context. Lancet 1990, 335:827-838.
2. MRC Working Party: Medical Research Council trial of treatment of hypertension in older adults: principal results. Br Med J 1992, 304:405-412.
3. Gerber JG, Nies AS: Antihypertensive agents and the drug therapy of hypertension. In: The Pharmacological Basis of Therapeutics. Edited by Gilman AG, Rall TW, Nies AS, Taylor P. Toronto: Pergamon Press; 1990:784-807.
4. Freis ED: How do diuretics lower blood pressure. Am Heart J 1983, 106:185-187.
5. Greger R: Chloride transport in thick ascending limb, distal convolution and collecting duct. Ann Rev Physiol 1988, 50:111-122.
6. Hayslett JP, Boulpaep EL, Giebisch GH: Factors influencing transepithelial potential difference in mammalian distal tubule. Am J Physiol 1978, 234:F182-F191.
7. Velazquez H, Wright FS, Good DW: Luminal influences on potassium secretion: chloride replacement with sulphate. Am J Physiol 1982, 242:F46-F54.
8. Conway J, Lauwers P: The hemodynamic and hypotensive effects of long-term therapy with chlorothiazide. Circulation 1959, 20:1028.
9. Van Brummelen P, Man In't Veld AJ, Schalekamp MADH: Hemodynamic changes during long-term thiazide treatment of essential hypertension in responders and nonresponders. Clin Pharmacol Ther 1980, 27:328-336.
10. Winer BM: The antihypertensive actions of benzothiadiazines. Circulation 1961, 23:211-218.
11. Winer BM: The antihypertensive mechanisms of salt depletion induced by hydrochlorothiazide. Circulation 1961, 24:788-796.
12. Tarazi RC, Dustan HP, Frohlich ED: Long-term thiazide therapy in essential hypertension. Circulation 1970, 41:709-717.
13. Bennett WM, McDonald WJ, Kuehnel E, Hartnett MN, Porter GA: Do diuretics have antihypertensive properties independent of natriuresis? Clin Pharmacol Ther 1977, 22:499-504.
14. Shah S, Khatri I, Freis ED: Mechanism of antihypertensive effect of thiazide diuretics. Am Heart J 1978, 95:611-618.
15. Hollander W, Chobanian AV, Wilkens RW: Studies on the antihypertensive action of chlorothiazide. Clin Res 1958, 6:21-22
16. Conway J, Palermo H: The vascular effect of the thiazide diuretics. Arch Intern Med 1963, 111:203-207.
17. Freis ED, Wanko A, Wilson IM, Parish AE: Chlorothiazide in hypertensive and normotensive patients. Ann NY Acad Med 1958, 71:450.
18. Dustan HP, Cumming GR, Corcoran AC, Page IH: A mechanism of chlorothiazide-enhanced effectiveness of antihypertensive ganglioplegic drugs. Circulation 1959, 19:360.
19. Calder JA, Schachter M, Sever P: Vascular wall prostanoid synthesis and the mode of action of novel vasodilator drugs. J Hypertens 1991, 9:S427-S428.
20. Calder JA, Schachter M, Sever P: Vasorelaxant actions of thiazides and related drugs. Br J Pharmacol 1992, 105:307P.
21. Calder JA, Schachter M, Sever P: Direct vascular actions of hydrochlorothiazide and indapamide in isolated small vessels. Eur J Pharmacol 1992, 220:19-26.
22. Kreye VAW, Bauer PK, Villhauer I: Evidence for furosemide-sensitive active chloride transport in vascular smooth muscle. Eur J Pharmacol 1981, 73:91-95.
23. Deth RC, Payne RA, Peecher DM: Influence of furosemide on Rubidium-86 uptake and alpha-adrenergic response of arterial smooth muscle. Blood Vessels 1987, 24:321-333.
24. Greenberg S, McGowan C, Xie J, Summer WR: Selective pulmonary and venous smooth muscle relaxation by furosemide: a comparison with morphine. J Pharmacol Exp Ther 1994, 270:1077-1085.
25. Ljung B: Nervous and myogenic mechanisms in the control of a vascular neuroeffector system. Acta Physiol Scand 1970, 349 (suppl) :33-68.
26. Rhodes HJ, Sutter MC: The action of diazoxide on isolated vascular smooth muscle electrophysiology and contraction. Can J Physiol Pharmacol 1971, 49:276-287.
27. Sutter MC: The mesenteric-portal vein in research. Pharmacol Rev 1990, 42:288-325.
28. Pillai G, Sutter MC: Effect of plasma from hypertensive patients on contractile response of vascular smooth muscle from normotensive rat. Can J Physiol Pharmacol 1989, 67:1272-1277.
29. Morledge JH: Clinical efficacy and safety of indapamide in essential hypertension. Am Heart J 1983, 106:229-232.
30. Hatt PY, Leblond JB : A comparative study of the activity of a new agent, indapamide, in essential arterial hypertension. Curr Med Res Opin 1975, 3:138-144.
31. Witchitz S, Kamoun A, Chiche P: A double-blind study in hypertensive patients of an original new compound, indapamide. Curr Med Res Opin 1975, 3:1-8.
32. Barbhaiya RH, Patel RB, Corrick-West HP, Joslin RS, Welling PG: Comparative bioavailability and pharmacokinetics of hydrochlorothiazide from oral tablet dosage forms determined by plasma level and urinary excretion methods. Biopharm Drug Dispos 1982, 3:329-336.
33. Mirroneau J, Mirroneau C: Indapamide and vascular smooth muscle cells. A review. JAMA 1988, 4:31-33.
34. Furchgott RF: The role of the endothelium in the responses of vascular smooth muscle to drugs. Annu Rev Pharmacol Toxicol 1984, 24:175-197.
35. Tian R, Aalkjaer C, Andreasen F: Mechanisms behind the relaxing effect of furosemide on the isolated rabbit ear artery. Pharmacol Toxicol 1991, 68:406-410.
36. Tobian L: Why do thiazide diuretics lower blood pressure in essential hypertension? Ann Rev Pharmacol 1967, 7:399-408.
37. Campbell DB, Boutin B: Vascular properties of indapamide and their relevance for the treatment of hypertension. Drugs Today 1989, 25(11):11.
38. Campbell DB, Brackman F: Cardiovascular protective properties of indapamide. Am J Cardiol 1990, 65:11H-27H.
39. Acchiardo SR, Skoutakis VA: Clinical efficacy safety and pharmacokinetics of indapamide in renal impairment. Am Heart J 1983, 106(1 pt 2):237-244.
40. Finch L, Hicks PE, Moore RA: Changes in vascular reactivity in experimental hypertensive animals following treatment with indapamide. J Pharm Pharmacol 1977, 29:739-743.
41. Finch L, Hicks PE, Moore RA: The effects of indapamide on vascular reactivity in experimental hypertension. Curr Med Res Opin 1977, 5 (suppl 1):44-54.
42. Borkowski KR, Hicks PE, Moore RA: The effects of indapamide on the responses to electrical stimulation of in vitro preparations from the rat Br J Pharmacol 1981, 72:172P-173P.
43. Moore RA, Seki T, Ohsumi S, Oheim K, Kynel J, Desnoyers P: Antihypertensive action of indapamide and review of pharmacology and toxicology. Curr Med Res Opin 1977, 5 (suppl 1):25-32.
44. Lebel M, Gbeassor FM, Grose JH: Role of prostanoids in the antihypertensive action of indapamide. Drugs Today 1989, 25:53.
45. Calder JA, Schachter M, Sever PS: Ion channel involvement in the acute vascular effects of thiazide diuretics and related compounds. J Pharmacol Exp Ther 1993, 265:1175-1180.
46. Liard JF: Influence of sodium withdrawal by a diuretic agent or peritoneal dialysis on arterial pressure in one-kidney Goldblatt hypertension in the rat. Pflugers Arch 1973, 344:109-115.
47. Mukherjee SK, Katz MA, Michael UF, Ogden DA: Mechanisms of hemodynamic actions of furosemide: differentiation of vascular and renal effects on blood pressure in functionally anephric hypertensive patients. Am Heart J 1981, 101:313-318.
48. Sechi LA, Palomba D, Bertoli E: Acute effects of furosemide on blood pressure in functionally anephric volume-expanded rats. Am J Nephrol 1993, 13:94-99.
49. Gerstheimer FP, Muhleisen M, Nehring D, Kreye VA: A chloride-bicarbonate exchanging anion carrier in vascular smooth muscle of the rabbit. Eur J Physiol 1987, 409:60-66.
50. Andreasen F, Christensen JH: The effect of furosemide on vascular smooth muscle is influenced by plasma protein. Pharm Toxicol 1988, 63:324-326.
51. Blair-West JR, McKinley MJ, McKenzie JS: Effect of furosemide on the reactivity of rat portal vein. J Pharm Pharmacol 1972, 24:442-446.