Synthesis, pharmacological characterization and QSAR studies on 2-substituted indole melatonin receptor ligands

Bioorganic and Medicinal Chemistry

Volumn 9, Issue 4, 2001, Pages 1045-1057

  Mor, Marco ^a   Spadoni, Gilberto ^b   Di Giacomo, Barbara ^b   Diamantini, Giuseppe ^b   Bedini, Annalida ^b   Tarzia, Giorgio ^b   Plazzi, Pier Vincenzo ^a   Rivara, Silvia ^a   Nonno, Romolo ^c   Lucini, Valeria ^c   Pannacci, Marilou ^c   Fraschini, Franco ^c   Stankov, Bojidar Michaylov ^c  

^a UNIVERSITY OF PARMA   (Italy)

^b UNIVERSITY OF URBINO   (Italy)

^c UNIVERSITY OF MILAN   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

INDOLE DERIVATIVE; MELATONIN DERIVATIVE; MELATONIN RECEPTOR; RECEPTOR SUBTYPE;

ARTICLE; BINDING AFFINITY; CELL STRAIN 3T3; CHEMICAL MODIFICATION; CHROMATOGRAPHY; DRUG CONFORMATION; DRUG RECEPTOR BINDING; DRUG STRUCTURE; DRUG SYNTHESIS; HUMAN; HUMAN CELL; LIPOPHILICITY; MULTIPLE REGRESSION; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; QUANTITATIVE STRUCTURE ACTIVITY RELATION;

3T3 CELLS; ALGORITHMS; ANIMALS; GUANOSINE 5'-O-(3-THIOTRIPHOSPHATE); HUMANS; INDOLES; LEAST-SQUARES ANALYSIS; LIGANDS; MELATONIN; MICE; MODELS, MOLECULAR; PROTEIN CONFORMATION; QUANTITATIVE STRUCTURE-ACTIVITY RELATIONSHIP; RECEPTORS, CELL SURFACE; RECEPTORS, CYTOPLASMIC AND NUCLEAR; RECEPTORS, MELATONIN; REGRESSION ANALYSIS;

EID: 0035023370     PISSN: 09680896     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0968-0896(00)00322-9     Document Type: Article

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