Effects of MDL 73005 on water-maze performances and locomotor activity in scopolamine-treated rats

Pharmacology Biochemistry and Behavior

Volumn 68, Issue 4, 2001, Pages 647-660

  Bertrand, Fabrice ^a   Lehmann, Olivia ^a   Galani, Rodrigue ^a   Lazarus, Christine ^a   Jeltsch, Hélène ^a   Cassel, Jean Christophe ^a  

^a CNRS   (France)

Author keywords

5 HT1A; Cholinergic; D2; Muscarinic; para Chlorophenylalanine; Rat; Serotonergic; Spatial reference memory; Spatial working memory

Indexed keywords

8 [2 [(2,3 DIHYDRO 1,4 BENZODIOXIN 2 YL)METHYLAMINO]ETHYL] 8 AZASPIRO[4.5]DECANE 7,9 DIONE; FENCLONINE; MUSCARINIC RECEPTOR; SCOPOLAMINE;

AMNESIA; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CONTROLLED STUDY; DRUG ACTIVITY; HYPERACTIVITY; LOCOMOTION; MALE; MAZE TEST; NONHUMAN; PRIORITY JOURNAL; RAT; RECEPTOR BLOCKING; SPATIAL MEMORY; WORKING MEMORY;

ANIMALS; BIOGENIC MONOAMINES; BRAIN; DIOXINS; FENCLONINE; MALE; MAZE LEARNING; MEMORY; MOTOR ACTIVITY; MUSCARINIC ANTAGONISTS; RATS; RATS, LONG-EVANS; RECEPTORS, SEROTONIN; SCOPOLAMINE; SEROTONIN AGONISTS; SEROTONIN ANTAGONISTS; SPIRO COMPOUNDS;

EID: 0035021743     PISSN: 00913057     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0091-3057(01)00448-8     Document Type: Article

References (53)

1. Review of central 5-HT receptors and their function
2. The effect of nonspatial water maze pretraining in rats subjected to serotonin depletion and muscarinic receptor antagonism: A detailed behavioural assessment of spatial performance
3. Intraseptal infusion of 8-OH-DPAT induces memory impairment in the rat: Effect on memory or anxiety?
4. Serotonin receptors in cognitive behaviors
5. Comparative behavioral and neurochemical activities of cholinergic antagonists in rats
6. 1A receptors
7. 1A receptors in the dorsal hippocampus impairs acquisition and performance of a spatial task in a water maze
8. 1A receptors in the hippocampus
9. 1A receptor antagonist, prevents the impairment of spatial learning caused by intrahippocampal scopolamine
10. 1A receptor antagonist, prevents the impairment of spatial learning caused by intrahippocampal administration of scopolamine or 7-chloro-kynurenic acid
11. 1A receptors in the dorsal raphe reverses the impairment of spatial learning caused by intrahippocampal scopolamine in rats
12. 1A receptor antagonist, prevents the impairment of spatial learning caused by blockade of hippocampal NMDA receptors
13. Serotonergic modulation of cholinergic function in the central nervous system: Cognitive implications
14. 1A binding in rat brain - A combined in situ hybridisation/in vitro receptor autoradiographic study
15. Dissociation of hippocampal and striatal contributions to spatial navigation in the water maze
16. Effects of central cholinergic blockade on striatal dopamine release measured with positron emission tomography in normal human subjects
17. The effect of para-chlorophenylalanine on spontaneous locomotor activity in the rat
18. 1A receptor function in the rat in vivo
19. 1A receptor agonists and antagonists: A comparison to adrenergic and dopaminergic neurons in rats
20. Combined pCPA and muscarinic antagonist treatment produces a deficit in rat water maze acquisition
21. WAY 100635 reverses 8-OH-DPAT-induced performance impairment in the radial maze
22. 1A receptor agonist, 8-OH-DPAT, preferentially activates cell body 5-HT autoreceptors in rat brain in vivo
23. Hippocampal 5-HT synthesis and release in vivo is decreased by infusion of 8-OHDPAT into the nucleus raphe dorsalis
24. 1A receptors mediate inhibition of tyrosine hydroxylation in rat striatum
25. 1A receptor agonists buspirone, ipsapirone and gepirone are inhibitors of tyrosine hydroxylation in rat striatum
26. Effects of the serotonin receptor agonists 8-OH-DPAT and TFMPP on learning as assessed using a novel water maze
27. Effects of the serotonin agonists 8-OH-DPAT, buspirone, and DOI on water maze performance
28. 1A autoreceptors of the dorsal and median raphe nuclei
29. Concomitant characterization of behavioral and striatal neurotransmitter response to amphetamine using in vivo microdialysis
30. Dissociable long-term cognitive deficits after frontal versus sensorimotor cortical contusions
31. Simultaneous determination of cholecystokinin-like immunoreactivity and dopamine release after treatment with veratrine, NMDA, scopolamine and SCH23390 in rat medial frontal cortex: A brain microdialysis study
32. Parallel information processing in the water maze: Evidence for independent memory systems involving dorsal striatum and hippocampus
33. Effect of scopolamine on the efflux of dopamine and its metabolites after clozapine, haloperidol or thioridazine
34. Acute scopolamine treatment decreases dopamine metabolism in rat hippocampus and frontal cortex
35. 5-HT system and cognition
36. 1A receptor-mediated activity in the rat: A pharmacological characterization of the actions of novel agonists and antagonists
37. 1A selective ligand and its effects in animal models of anxiety: Comparison with buspirone, 8-OH-DPAT and diazepam
38. The influence of serotoninergic drugs on dopaminergic neurotransmission in rat substantia nigra, striatum and limbic forebrain in vivo
39. Quantitative autoradiographic mapping of serotonin receptors in the rat brain: I. Serotonin-1 receptors
40. Muscarinic antagonists attenuate neurotensin-stimulated accumbens and striatal dopamine metabolism
41. Influence of serotoninergic drugs on in vivo dopamine extracellular output in rat striatum
42. Involvement of the posteroventral caudate-putamen in memory consolidation in the Morris water maze
43. 2 dopamine receptor blockade immediately post-training enhances retention in hidden and visible platform versions of the water maze
44. Dose-response curves and time-course effects of selected anticholinergics on locomotor activity in rats
45. 1A receptor ligand
46. Microinjections of d-amphetamine into the nucleus accumbens and caudate-putamen differentially affect stereotypy and locomotion in the rat
47. The use of microwave heating to inactivate cholinesterase in the rat brain prior to analysis for acetylcholine
48. The role of serotonergic-cholinergic interactions in the mediation of cognitive behaviour
49. 1A ligand MDL 73005EF in the rat hippocampal slice
50. Impairments in the acquisition, retention and selection of spatial navigation strategies after medial caudate-putamen lesions in rats
51. 1A receptor activation increases hippocampal acetylcholine efflux and motor activity in the guinea pig: Agonist efficacy influences functional activity in vivo
52. 1A receptors in memory