메뉴 건너뛰기




Volumn 23, Issue 4, 2001, Pages 532-565

Mecamylamine: New therapeutic uses and toxicity/risk profile

Author keywords

Mecamylamine; Neuropsychiatric; Nicotinic acetylcholine receptor antagonist; Review

Indexed keywords

MECAMYLAMINE; N METHYL DEXTRO ASPARTIC ACID; NICOTINIC RECEPTOR; NICOTINIC RECEPTOR BLOCKING AGENT;

EID: 0035019499     PISSN: 01492918     EISSN: 1879114X     Source Type: Journal    
DOI: 10.1016/S0149-2918(01)80059-X     Document Type: Article
Times cited : (83)

References (134)
  • 6
    • 0030980834 scopus 로고    scopus 로고
    • The molecular biology of neuronal nicotinic acetylcholine receptors
    • (1997) Crit Rev Toxicol , vol.27 , pp. 299-318
    • Boyd, R.T.1
  • 7
    • 0025934097 scopus 로고
    • Both alpha- and beta-subunits contribute to the agonist sensitivity of neuronal nicotinic acetylcholine receptors
    • (1991) J Neurosci , vol.11 , pp. 837-845
    • Luetje, C.W.1    Patrick, J.2
  • 16
    • 0004961237 scopus 로고
    • Actions of mecamylamine, dimecamine, pempidine and their two quaternary metho-salts at the neuromuscular junction
    • (1964) Br J Pharmacol , vol.22 , pp. 56-65
    • Blackman, J.G.1    Ray, C.2
  • 25
    • 0015017157 scopus 로고
    • Effects of mecamylamine on responses of carotid body chemoreceptors in vivo to physiological and pharmacological stimuli
    • (1971) J Physiol (Lond) , vol.212 , pp. 655-666
    • Sampson, S.R.1
  • 30
  • 37
    • 0013882777 scopus 로고
    • The mechanism of gastric hyperacidity produced by pylorus ligation in the rat
    • (1966) Am J Dig Dis , vol.11 , pp. 231-241
    • Brodie, D.A.1
  • 51
    • 0017280469 scopus 로고
    • Nicotine-like behavioral effect after small dose of mecamylamine in Roman high-avoidance rats
    • (1976) Psychopharmacologia , vol.46 , pp. 119-121
    • Driscoll, P.1
  • 52
    • 0018578096 scopus 로고
    • Effects of nicotine, mecamylamine, and hexamethonium on shock-induced fighting, pain reactivity, and locomotor behaviour in rats
    • (1979) Psychopharmacology (Berl) , vol.66 , pp. 93-98
    • Rodgers, R.J.1
  • 59
    • 0029028455 scopus 로고
    • Excitatory amino acids and drugs of abuse: A role for N-methyl-D-aspartate receptors in drug tolerance, sensitization and physical dependence
    • (1995) Drug Alcohol Depend , vol.38 , pp. 139-154
    • Trujillo, K.A.1    Akil, H.2
  • 60
    • 0034004755 scopus 로고    scopus 로고
    • In search of a new pharmacological treatment for drug and alcohol addiction: N-methyl-D-aspartate (NMDA) antagonists
    • (2000) Drug Alcohol Depend , vol.59 , pp. 1-15
    • Bisaga, A.1    Popik, P.2
  • 62
    • 0024601253 scopus 로고
    • Effects of nicotinic agonists and antagonists on N-methyl-D-aspartate-induced 3H-norepinephrine release and 3H-(1-[1-(2-thienyl) cyclohexyl]-piperidine) binding in rat hippocampus
    • (1989) Synapse , vol.3 , pp. 129-135
    • Snell, L.D.1    Johnson, K.M.2
  • 65
    • 0023815466 scopus 로고
    • Mecamylamine is a selective non-competitive antagonist of N-methyl-D-aspartate- and aspartate-induced currents in horizontal cells dissociated from the catfish retina
    • (1988) Neurosci Lett , vol.94 , pp. 93-98
    • O'Dell, T.J.1    Christensen, B.N.2
  • 66
    • 0016138565 scopus 로고
    • Ketamine catalepsy and anesthesia in dogs pretreated with antiserotonergic or antidopaminergic neuroleptics or with anticholinergic agents
    • (1974) Pharmacol Res Commun , vol.6 , pp. 289-299
    • Hatch, R.C.1
  • 67
    • 0016441071 scopus 로고
    • The influence of adrenergic, dopaminergic, cholinergic and serotoninergic drugs on plasma prolactin levels in ovariectomized, estrogen-treated rats
    • (1975) Endocrinology , vol.96 , pp. 313-318
    • Lawson, D.M.1    Gala, R.R.2
  • 68
    • 0004931490 scopus 로고
    • Effect of ganglionic blocking agents on glucose metabolism in the fasting rat
    • Abstract
    • (1971) Diabetes , vol.20 , Issue.SUPPL. 1 , pp. 381
    • Turinsky, J.1
  • 69
    • 0015962475 scopus 로고
    • Effect of ganglionic blocking agents chlorisondamine and mecamylamine on glucose metabolism and serum insulin in the rat
    • (1974) Proc Soc Exp Biol Med , vol.145 , pp. 25-31
    • Turinsky, J.1
  • 70
    • 0020564506 scopus 로고
    • Effects of cholinergic and dopaminergic agents on pain and morphine analgesia measured by three pain tests
    • (1983) Exp Neurol , vol.81 , pp. 167-176
    • Dennis, S.G.1    Melzack, R.2
  • 74
    • 0004955372 scopus 로고
    • Pharmacological properties of pempidine (1:2:2:6:6-pentamethylpiperidine), a new ganglion-blocking compound
    • (1958) Br J Pharmacol , vol.13 , pp. 339-349
    • Corne, S.J.1    Edge, N.D.2
  • 81
    • 0030175612 scopus 로고    scopus 로고
    • Nicotinic receptors in the development and modulation of CNS synapses
    • (1996) Neuron , vol.16 , pp. 1077-1085
    • Role, L.W.1    Berg, D.K.2
  • 105
    • 0028148801 scopus 로고
    • Overview: Biological processes relevant to drugs of dependence
    • (1994) Addiction , vol.89 , pp. 1443-1446
    • Grunberg, N.E.1
  • 112
    • 0033983916 scopus 로고    scopus 로고
    • Tourette syndrome, associated conditions and the complexities of treatment
    • (2000) Brain , vol.123 , pp. 425-462
    • Robertson, M.M.1
  • 116
  • 119
  • 122
  • 129
    • 0032934644 scopus 로고    scopus 로고
    • Noncompetitive functional inhibition at diverse, human nicotinic acetylcholine receptor subtypes by bupropion, phencyclidine, and ibogaine
    • (1999) J Pharmacol Exp Ther , vol.288 , pp. 88-92
    • Fryer, J.D.1    Lukas, R.L.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.