Peptide and small molecule microarray for high throughput cell adhesion and functional assays

Bioconjugate Chemistry

Volumn 12, Issue 3, 2001, Pages 346-353

  Falsey, James R ^a   Renil, M ^a   Park, Steven ^a   Li, Shijun ^a   Lam, Kit S ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

(3 AMINOPROPYL)TRIETHOXYSILANE; CARBOXY TERMINAL SEQUENCE; CELL ADHESION; CHEMICAL MODIFICATION; COVALENT BOND; CULTURE VESSEL; DNA MICROARRAY; ENZYME SPECIFICITY; GLYOXYLIC ACID DERIVATIVE; LIGAND; MICROSCOPY; PROTEIN KINASE;

AMINO ACIDS; BIOCHEMISTRY; CELL ADHESION; CELL CULTURE; CELL SIGNALING; CELLS; CHEMICAL DETECTION; FLUORESCENCE; LIGANDS; MICROPROCESSOR CHIPS; MOLECULES;

CELL-ADHESION ASSAYS; COVALENT ATTACHMENT; DEPROTECTION; FUNCTIONAL ASSAYS; GLASS MICROSCOPE SLIDES; HIGH-THROUGHPUT; MOLECULE LIGANDS; SITE-SPECIFIC; SMALL MOLECULE MICROARRAYS; SMALL MOLECULES;

PEPTIDES;

EID: 0035017737     PISSN: 10431802     EISSN: None     Source Type: Journal    
DOI: 10.1021/bc000141q     Document Type: Article

References (42)

1. Merrifield, R. B. (1963) Solid-phase peptide synthesis I The synthesis of a tetrapeptide. J. Am. Chem. Soc. 85, 2149-2154
2. Lam, K. S. (1997) Application of combinatorial library methods in cancer research and drug discovery. Anti-Cancer Drug Design 12, 145-167.
3. Renil, M., Ferreras, M., Delaisse, J. M., Foged, N. T., and Meldal, M. (1998) PEGA supports for combinatorial peptide synthesis and solid-phase enzymatic library assays. J. Pept. Sci. 4, 195-210.
4. Dolle, R. E., and Nelson, N., Jr. (1999) Comprehensive survey of combinatorial library synthesis: 1998. J. Comb. Chem. 1 (4), 235-282.
5. St. Hilaire, P. M., and Meldal, M. (2000) Glycopeptide and oligosaccharide libraries. Angew. Chem., Int. Ed. 39, 1162-1179.
6. Lam, K. S., Salmon, S. E., Hersh, E. M., Hruby, V. J., Kazmierski, W. M., and Knapp, R. J. (1991) One-bead, One-peptide: A new type of synthetic peptide library for identifying ligand-binding activity. Nature 354, 82-83.
7. Lam, K. S., Krchnak, V., and Lebl, M. (1997) The "one-bead one-compound" combinatorial library method. Chem. Rev. 97, 411-448.
8. Furka, A., Sebestyen, F., Asgedom, M., and Dibo, G. (1991) General method for rapid synthesis of multicomponent peptide mixtures. Int. J. Pept. Protein Res. 37, 487-493.
9. Houghten, R. A., Pinilla, C., Blondelle, S. E., Appel, J. R., Dooley, C. T., and Cuervo, J. H. (1991) Generation and use of synthetic peptide combinatorial libraries for basic research and drug discovery. Nature 354, 84-86.
10. Lam, K. S., Hruby, V. J., Lebl, M., Kazmierski, W. M., Hersh, E. M., and Salmon, S. E. (1993) The chemical synthesis of large random peptide libraries and their use for the discovery of ligands for macromolecular acceptors. Bioorg. Med. Chem. Lett. 3, 419-424.
11. Lam, K. S., Lebl, M., Krchnak, V., Wade, S., Abdul-Latif, F., Ferguson, R., Cuzzocrea, C., and Wertman, K. (1993) Discovery of D-amino acid containing ligands with Selectide technology. Gene 137, 13-16.
12. Lam, K. S., and Lebl, M. (1992) Streptavidin and avidin recognize peptide ligands with different motifs. Immuno-Methods 1, 11-15.
13. Lam, K. S., and Lebl, M. (1994) Selectide technology - bead binding screening. Methods: A Companion to Methods in Enzymology 6, 372-380.
14. Lam, K. S., Zhao, Z. G., Wade, S., Krchnak, V., and Lebl, M. (1994) Identification of small peptides that interact specifically with a small organic dye. Drug Dev. Res. 33, 157-160.
15. Wu, J., Ma, Q. N., and Lam, K. S. (1994) Identifying substrate motifs of protein kinases by a random library approach. Biochemistry 33, 14825-14833.
16. Lam, K. S., Wu, J. S., and Lou, Q. (1995) Identification and characterization of a novel peptide substrate specific for src-family tyrosine kinase. Int. J. Protein Pept. Res. 45, 587-592.
17. c-src protein tyrosine kinase. Bioorg. Med. Chem. 4, 677-682.
18. Pennington, M. E., Lam, K. S., and Cress, A. E. (1996) Mol. Divers. 2, 19-28.
19. Schena, M., Shalon, D., Heller, R., Chai, A., Brown, P. O., and Davis, R. W. (1996) Parallel human genome analysis: Microarray-based expression monitoring of 1000 genes. Proc. Natl. Acad. Sci. 93, 10614-10619.
20. Niemeyer, C. M., and Blohm, D. (1999) DNA microarrays. Angew. Chem. Int. Ed. 39, 2865-2869.
21. Falsey, J., Li, S., and Lam, K. S. (2000) Development of a chemical microarray technology. In Peptides: Chemistry, Structure and Biology (Proceeding of the 16th American Peptide Symposium, June 26-July 1, 1999), pp 736-737.
22. MacBeath, G., Hoehler, A. N., and Schreiber, S. L. (1999) Printing small molecules as microarrays an detecting protein-ligand interactions en Masse. J. Am. Chem. Soc. 121, 7967-7968.
23. MacBeath, G., and Schreiber, S. L. (2000) Printing proteins as microarrays for high-throughput function determination. Science 289, 1760-1763.
24. Frank, R. (1992) Spot-Synthesis: An easy technique for the positionally addressable, parallel chemical synthesis on a membrane support. Tetrahedron 48, 9217-9232.
25. Fodor, S., Read, J. L, Pirrung, M. C., Stryer, L., Tsai Lu, A., and Solas, D. (1991) Light-directed, spatially addressable parallel chemical synthesis. Science 251, 767-773.
26. (a) Pellois, J. P., Wang, W., and Gao, X. (2000) Peptide synthesis based on t-Boc chemistry and solution photogenerated acids. J. Comb. Chem. 2 (4), 355-60.
27. (b) LeProust, E., Pellois, J. P., Yu, P., Zhang, H., Gao, X., Srivannavit O., Gulari, E., and Zhou, X. (2000) Digital light-directed synthesis. A microarray platform that permits rapid reaction optimization on a combinatorial basis. J. Comb. Chem. 2 (4), 349-354.
28. Arenkove, P., Kukhtin, A., Gemmell, A., Voloshchuk, S., Chupeeva, V., and Mirzabekov, A. (2000) Protein microchips: use for immunoassay and enzymatic reactions Anal. Biochem. 278, 123-131.
29. Mendoza, L. G., McQuarry, P., Mongan, A., Gangadharan, R., Brignac, S., and Eggers, M. (1999) High-throughput microarray-based enzyme-linked immunosorbent assay (ELISA) BioTechniques 27, 778-788.
30. Zammatteo, N., Jeanmart, L., Hamels, S., Courtois, S., Louette, P., Hevesi, L., and Remacel, J. (2000) Comparison between different strategies of covalent attachment of DNA to glass surfaces to build DNA microarrays Anal. Biochem. 280, 143-150.
31. Joos, B., Kuster, H., and Cone, R. (1997) Covalent attachment of hybridizable oligonucleotides to glass supports. Anal. Biochem. 247, 96-101.
32. Liu, C. F., Rao, C., and Tam, J. P. (1996) Orthogonal ligation of unprotected peptide segments through pseudoproline formation for the synthesis of HIV-1 protease analogues. J. Am. Chem. Soc. 118, 307-312.
33. Shao J., and Tam J. P. (1995) Unprotected peptides as building blocks for the synthesis of peptide dendrimers with oxime, hydrazone, and thiazolidine linkages. J. Am. Chem. Soc. 117, 3893-3899.
34. Wahl F., and Mutter M. (1996) Analogues of oxytocin with an oxime bridge using chemoselectively addressable building blocks. Tetrahedron Lett. 37, 6861.
35. Tam, J. P., Yu, W., and Miao, Z. (1999) Orthogonal ligation strategies for peptides and proteins. Biopolymers (Pept. Sci.) 51, 311-332.
36. Zhao, Z.-G., and Lam, K. S. (1995) A novel approach for iodolabeling synthetic peptides. J. Chem. Soc., Chem. Commun. 1739-1740.
37. Zhao, Z.-G., Im, J. S., Lam, K. S., and Lake, D. (1999) Site specific modification of a single chain antibody using a novel glyoxylyl-based labeling reagent. Bioconjugate Chem. 10, 424-430.
38. Lam, K. S., Lake, D., Salmon, S. E., et al. (1996) A one-bead one-peptide combinatorial library method for B-cell epitope mapping. Methods: a Companion to Methods in Enzymology 9, 482-493.
39. Songyang, Z., Carrway, K. L., III, Eck, M. J., et al. (1995) Catalytic specificity of protein tyrosine kinases is critical for selective signaling. Nature 373, 536.
40. Al-Obeidi, F. A., Wu, J. J., and Lam, K. S. (1998) Protein tyrosine kinases: Structure, substrate, specificity, and drug discovery. Biopolymers (Pept. Sci.) 47, 197-203.
41. Lam, K. S. et al. (1995) Idiotype specific peptides bind to the surface immunoglobulins of two murine B-cell lymphoma lines, inducing signal transduction. Biomed. Pept., Proteins Nucleic Acids 1, 205-210.
42. Lam, K. S., and Zhao, Z.-G. (1997) Targeted therapy for lymphoma with peptides. Hematology/Oncology Clinic of North America 11, 1007-1019.