Factors that predict preexisting colonization with antibiotic-resistant gram-negative bacilli in patients admitted to a pediatric intensive care unit

Pediatrics

Volumn 103, Issue 4 I, 1999, Pages 719-723

  Toltzis, Philip ^a,b   Hoyen, Claudia ^a   Spinner Block, Sara ^a   Salvator, Ann E ^a   Rice, Louis B ^a  

^a CASE WESTERN RESERVE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b CASE WESTERN RESERVE UNIVERSITY   (United States)

Author keywords

Antibiotic resistance; Disease transmission; Gram negative aerobic bacteria; Nosocomial infections; Pediatric intensive care unit; Pulsed field gel electrophoresis

Indexed keywords

ANTIBIOTIC AGENT; CEFTAZIDIME; TOBRAMYCIN;

ANTIBIOTIC RESISTANCE; ARTICLE; BACTERIAL COLONIZATION; CONTROLLED STUDY; DRUG EXPOSURE; GRAM NEGATIVE BACTERIUM; HOSPITAL ADMISSION; HOUSEHOLD; HUMAN; INTENSIVE CARE UNIT; INTRAVENOUS DRUG ADMINISTRATION; LONG TERM CARE; MAJOR CLINICAL STUDY; ORAL DRUG ADMINISTRATION; PEDIATRICS; PRIORITY JOURNAL;

EID: 0033030907     PISSN: 00314005     EISSN: None     Source Type: Journal    
DOI: 10.1542/peds.103.4.719     Document Type: Article

References (23)

1. Burwen DR, Banerjee SN, Gaynes RP. Ceftazidime resistance among selected nosocomial gram-negative bacilli in the United States. J Infect Dis. 1994;170:1622-1625
2. Sirot DL, Goldstein RW, Soussy CJ, et al. Resistance to cefotaxime and seven other β-lactams in member of the family Enterobacteriaceae: a 3-year survey in France. Antimicrob Agents Chemother. 1992;36:1677-1681
3. Itokazu GS, Quinn JP, Bell-Dixon C, Kahan FM, Weinstein RA. Antimicrobial resistance rates among aerobic gram-negative bacilli recovered from patients in intensive care units: evaluation of a national postmarketing surveillance program. Clin Infect Dis. 1996;23:779-784
4. Archibald L, Phillip L, Monnet D, McGowan JE, Tenover F, Gaynes R. Antimicrobial resistance in isolates from inpatients and outpatients in the United States: increasing importance of the intensive care unit. Clin Infect Dis. 1997;24:211-215
5. Olson B, Weinstein RA, Nathan C, Chamberlain W, Kabins SA. Epidemiology of endemic Pseudomonas aeruginosa: why infection control efforts have failed. J Infect Dis. 1984;150:808-816
6. Flynn DM, Weinstein RA, Nathan C, Gaston MA, Kabins SA. Patients' endogenous flora as a source of ""nosocomial" Enterobacter in cardiac surgery. J Infect Dis. 1987;156:363-368
7. Bingen E, Denamur E, Lambert-Zechovsky N, Brahimi N, El Lakany M, Elion J. Rapid genotyping shows the absence of cross-contamination in Enterobacter cloacae nosocomial infections. J Hosp Infect. 1992;21:95-101
8. Weinstein RA. Epidemiology and control of nosocomial infections in adult intensive care units. Am J Med. 1991;91(suppl 13B):179S-184S
9. Orsi GB, Mansi A, Tomao P, Chiarini F, Visca P. Lack of association between clinical and environmental isolates of Pseudomonas aeruginosa in hospital wards. J Hosp Infect. 1994;27:49-60
10. Chetchotisakd P, Phelps CL, Harstein AI. Assessment of bacterial cross-contamination as a cause of infections in patients in intensive care units. Clin Infect Dis. 1994;18:929-937
11. Rice LB, Toltzis P. Antibiotic use and resistance in the intensive care unit. Curr Opin Crit Care. 1997;3:348-354
12. Shlaes DM, Gerding DN, John JF, et al. Society for Healthcare Epidemiology of American and Infectious Diseases Society of America Joint Committee on the Prevention of Antimicrobial Resistance: guidelines for the prevention of antimicrobial resistance in hospitals. Clin Infect Dis. 1997;25:584-599
13. Toltzis P, Yamashita T, Vilt R, Blumer JL. Colonization with antibiotic-resistant gram-negative organisms in a pediatric intensive care unit. Crit Care Med. 1997;25:538-544
14. Toltzis P, Yamashita T, Vilt L, et al. Antibiotic restriction does not alter endemic colonization with resistant gram negative rods in a pediatric intensive care unit. Crit Care Med. 1998;26:1893-1899
15. Tenover FC, Arbeit RD, Goering RV, et al. Interpreting chromosomal DNA restriction pattern produced by pulse-field gel electrophoresis: criteria for bacterial strain typing. J Clin Microbiol. 1995;33:2233-2239
16. Johanson WG, Pierce AK, Sanford JP. Changing pharyngeal bacterial flora of hospitalized patients: emergence of gram negative bacteria. N Engl J Med. 1969;281:1137-1140
17. Schwartz SN, Dowling JN, Benkovic C, DeQuittner-Buchanan M, Prostko T, Yee RB. Sources of gram-negative bacilli colonizing the trachea of intubated patients. J Infect Dis. 1978;138:227-231
18. Gaynes RP, Weinstein RA, Chamberlin W, Kabins SA. Antibiotic-resistant flora in nursing home patients admitted to the hospital. Arch Intern Med. 1985;145:1804-1807
19. John Jr JE, Ribner BS. Antibiotic resistance in long-term care facilities. Infect Control Hosp Epidemiol. 1991;12:245-250
20. Thurn JR, Crossley K, Gerdts A. Bacterial colonization of nursing home residents on admission to an acute care hospital. J Hosp Infect. 1996;32: 127-133
21. Terpenning MS, Bradley SF, Wan JY, Chenoweth CE, Jorgensen KA, Kauffman CA. Colonization and infection with antibiotic-resistant bacteria in a long-term care facility. J Am Geriatr Soc. 1994;42:1062-1069
22. Leistevuo T, Leistevuo J, Osterblad M, et al. Antimicrobial resistance of fecal aerobic gram-negative bacilli in different age groups in a community. Antimicrob Agents Chemother. 1996;40:1931-1934
23. Levy SB, Marshall B, Schluederberg S, Rowse D, Davis J. High frequency of antimicrobial resistance in human fecal flora. Antimicrob Agents Chemother. 1988;32:1801-1806