Cross-talk between the signals hypoxia and glucose at the glucose response element of the L-type pyruvate kinase gene

Endocrinology

Volumn 142, Issue 6, 2001, Pages 2707-2718

  Krones, Anja ^a   Jungermann, Kurt ^a   Kietzmann, Thomas ^a,b  

^a UNIVERSITY OF GÖTTINGEN   (Germany)

^b Inst fur Biochem und Molek Z   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

GENE PRODUCT; GLUCOSE DERIVATIVE; GLUCOSE RESPONSE ELEMENT; HYPOXIA INDUCIBLE FACTOR 1; LUCIFERASE; MESSENGER RNA; OXYGEN; PYRUVATE KINASE; UNCLASSIFIED DRUG; UPSTREAM STIMULATING FACTOR;

ANGIOGENESIS; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CARCINOGENESIS; CELL CULTURE; CONTROLLED STUDY; EMBRYO DEVELOPMENT; ENZYME REGULATION; GENE EXPRESSION; HYPOXIA; LIVER; LIVER CELL; MALE; METABOLISM; NONHUMAN; NUCLEOTIDE SEQUENCE; OXYGEN TENSION; PATHOPHYSIOLOGY; PRIORITY JOURNAL; RAT; SIGNAL TRANSDUCTION;

EID: 0035009567     PISSN: 00137227     EISSN: None     Source Type: Journal    
DOI: 10.1210/endo.142.6.8200     Document Type: Article

References (59)

1. 1. Yamada K, Noguchi T 1999 Nutrient and hormonal regulation of pyruvate kinase gene expression. Biochem J 337:1-11
2. 2. Noguchi T, Iritani N, Tanaka T 1992 Molecular mechanism of induction of key enzymes related to lipogenesis. Proc Soc Exp Biol Med 200:206-209
3. 3. Bunn HF, Poyton RO 1996 Oxygen sensing and molecular adaptation to hypoxia. Physiol Rev 76:839-885
4. 2. Biochem J 321:17-20
5. 5. Carmeliet P, Dor Y, Herbert JM, Fukumura D, Brusselmans K, Dewerchin M, Neeman M, Bono F, Abramovitch R, Maxwell P, Koch CJ, Ratcliffe P, Moons L, Jain RK, Collen D, Keshet E 1998 Role of HIF-1α in hypoxia-mediated apoptosis, cell proliferation and tumour angiogenesis. Nature 394:485-490
6. 6. Ryan HE, Lo J, Johnson RS 1998 HIF-1 alpha is required for solid tumor formation and embryo nic vascularization. EMBO J 17:3005-3015
7. 7. Dang CV, Lewis BC, Dolde C, Dang G, Shim H 1997 Oncogenes in tumor metabolism, tumorigenesis, and apoptosis. J Bioenerg Biomembr 29:345-354
8. 8. Sasse D, Spornitz UM, Maly IP 1992 Liver architecture. Enzyme 46:8-32
9. 9. Jungermann K, Katz N 1989 Functional specialization of different hepatocyte populations. Physiol Rev 69:708-764
10. 10. Häussinger D, Lamers WH, Moorman AF 1992 Hepatocyte heterogeneity in the metabolism of amino acids and ammonia. Enzyme 46:72-93
11. 11. Gebhardt R, Gaunitz F, Mecke D 1994 Heterogeneous (positional) expression of hepatic glutamine synthetase: features, regulation and implications for hepatocarcinogenesis. Adv Enzyme Regul 34:27-56
12. 12. Jungermann K 1995 Zonation of metabolism and gene expression in liver. Histochem Cell Biol 103:81-91
13. 13. Jungermann K, Kietzmann T 1996 Zonation of parenchymal and nonparenchymal metabolism in liver. Annu Rev Nutr 16:179-203
14. 14. Jungermann K, Kietzmann T 2000 Oxygen Modulator of metabolic zonation and disease of the liver. Hepatology 31:255-260
15. 15. Zierz S, Katz N, Jungermann K 1983 Distribution of pyruvate kinase type L and M2 in microdissected periportal and perivenous rat liver tissue with different dietary states. Hoppe Seylers Z Physiol Chem 364:1447-1453
16. 16. Vaulont S, Puzenat N, Levrat F, Cognet M, Kahn A, Raymondjean M 1989 Proteins binding to the liver-specific pyruvate kinase gene promoter. A unique combination of known factors. J Mol Biol 209:1205-219
17. 17. Bergot MO, Diaz GM, Puzenat N, Raymondjean M, Kahn A 1992 Cis-regulation of the L-type pyruvate kinase gene promoter by glucose, insulin and cyclic AMP. Nucleic Acids Res 20:1871-1877
18. 18. Kahn A 1997 Transcriptional regulation by glucose in the liver. Biochimie (Paris) 79:113-118
19. 19. Nauck M, Wolfle D, Katz N, Jungermann K 1981 Modulation of the glucagon-dependent induction of phosphoenolpyruvate carboxykinase and tyrosine aminotransferase by arterial and venous oxygen concentrations in hepatocyte cultures. Eur J Biochem 119:657-661
20. 20. Hellkamp J, Christ B, Bastian H, Jungermann K 1991 Modulation by oxygen of the glucagon-dependent activation of the phosphoenolpyruvate carboxykinase gene in rat hepatocyte cultures. Eur J Biochem 198:635-639
21. 21. Lone YC, Simon MP, Kahn A, Marie J 1986 Complete nucleotide and deduced amino acid sequences of rat L-type pyruvate kinase. FEBS Lett 195:97-100
22. 22. Cognet M, Bergot MO, Kahn A 1991 Cis-acting DNA elements regulating expression of the liver pyruvate kinase gene in hepatocytes and hepatoma cells. Evidence for tissue-specific activators and extinguisher. J Biol Chem 266:7368-7375
23. 23. Semenza GL, Wang GL 1992 A nuclear factor induced by hypoxia via de novo protein synthesis binds to the human erythropoietin gene enhancer at a site required for transcriptional activation. Mol Cell Biol 12:5447-5454
24. 24. Kietzmann T, Roth U, Jungermann K 1999 Induction of the plasminogen activator inhibitor-1 gene expression by mild hypoxia via a hypoxia response element binding the hypoxia-inducible factor-1 in rat hepatocytes. Blood 94:4177-4185
25. 25. Reisz PS, Probst MR, Fukunaga BN, Hankinson O 1994 Identification of functional domains of the aryl hydrocarbon receptor nuclear translocator protein (ARNT). Mol Cell Biol 14:6075-6086
26. 26. Immenschuh S, Hinke V, Ohlmann A, Gifhorn-Katz S, Katz N, Jungermann K, Kietzmann T 1998 Transcriptional activation of the heme oxygenase-1 gene by cGMP via a cAMP response element/activator protein-1 element in primary cultures of rat hepatocytes. Biochem J 334:141-146
27. 27. Wiesener MS, Turley H, Allen WE, Willam C, Eckardt KU, Talks KL, Wood SM, Gatter KC, Harris AL, Pugh CW, Ratcliffe PJ, Maxwell PH 1998 Induction of endothelial PAS domain protein-1 by hypoxia: characterization and comparison with hypoxia-inducible factor-1α. Blood 92:2260-2268
28. 28. Laemmli UK, Beguin F, Gujer KG 1970 A factor preventing the major head protein of bacteriophage T4 from random aggregation. J Mol Biol 47:69-85
29. 29. Domingo M, Einig C, Eigenbrodt E, Reinacher M 1992 Immunohistological demonstration of pyruvate kinase isoenzyme type L in rat with monoclonal antibodies. J Histochem Cytochem 40:665-673
30. 30. Dignam JD, Lebovitz RM, Roeder RG 1983 Accurate transcription initiation by RNA polymerase II in a soluble extract from isolated mammalian nuclei. Nucleic Acids Res 11:1475-1489
31. 31. Moorman AF, De BP, Charles R, Lamers WH 1991 Pericentral expression pattern of glucokinase mRNA in the rat liver lobulus. FEBS Lett 287:47-52
32. 32. Gebhardt R, Ebert A, Bauer G 1988 Heterogeneous expression of glutamine synthetase mRNA in rat liver parenchyma revealed by in situ hybridization and Northern blot analysis of RNA from periportal and perivenous hepatocytes. FEBS Lett 241:89-93
33. 33. Doiron B, Cuif MH, Kahn A 1996 Glucose catabolism induces the L-type pyruvate kinase gene (125a). Biochem Soc Trans 24:250S
34. 34. Kvietikova I, Wenger RH, Marti HH, Gassmann M 1997 The hypoxia-inducible factor-1 DNA recognition site is cAMP-responsive. Kidney Int 51:564-566
35. 35. Diaz GM, Bergot MO, Martinez A, Cuif MH, Kahn A, Raymondjean M 1993 Functional characterization of the L-type pyruvate kinase gene glucose response complex. Mol Cell Biol 13:7725-7733
36. 36. Kietzmann T, Jungermann K 1997 Modulation by oxygen of zonal gene expression in liver studied in primary rat hepatocyte cultures. Cell Biol Toxicol 13:243-255
37. 37. Kietzmann T, Freimann S, Bratke J, Jungermann K 1996 Regulation of the gluconeogenic phosphoenolpyruvate carboxykinase and glycolytic aldolase A gene expression by O2 in rat hepatocyte cultures. Involvement of hydrogen peroxide as mediator in the response to O2. FEBS Lett 388:228-232
38. 38. Towle HC 1995 Metabolic regulation of gene transcription in mammals. J Biol Chem 270:23235-23238
39. 39. Krones A, Kietzmann T, Jungermann K 1998 Periportal localization of glucagon receptor mRNA in rat liver and regulation of its expression by glucose and oxygen in hepatocyte cultures. FEBS Lett 421:136-140
40. 40. Girard J, Ferre P, Foufelle F 1997 Mechanisms by which carbohydrates regulate expression of genes for glycolytic and lipogenic enzymes. Annu Rev Nutr 17:325-352
41. 41. Casado M, Vallet VS, Kahn A, Vaulont S 1999 Essential role in vivo of upstream stimulatory factors for a normal dietary response of the fatty acid synthase gene in the liver. J Biol Chem 274:2009-2013
42. 42. Sul HS, Wang D 1998 Nutritional and hormonal regulation of enzymes in fat synthesis: studies of fatty acid synthase and mitochondrial glycerol-3-phosphate acyltransferase gene transcription. Annu Rev Nutr 18:331-351
43. 43. Prip-Buus C, Perdereau D, Foufelle F, Maury J, Ferre P, Girard J 1995 Induction of fatty-acid-synthase gene expression by glucose in primary culture of rat hepatocytes. Dependency upon glucokinase activity. Eur J Biochem 231:309-315
44. 44. Foufelle F, Gouhot B, Pegorier JP, Perdereau D, Girard J, Ferre P 1992 Glucose stimulation of lipogenic enzyme gene expression in cultured white adipose tissue. A role for glucose 6-phosphate. J Biol Chem 267:20543-20546
45. 45. Kietzmann T, Jungermann K 1997 Metabolic zonation of liver parenchyma and its short-term and long-term regulation. In: Vidal-Vanaclocha F (ed) Functional Heterogeneity of liver tissue. R.G. Landes Company, Texas, pp 1-42
46. 46. Lou DQ, Tannour M, Selig L, Thomas D, Kahn A, Vasseur CM 1999 Chicken ovalbumin upstream promoter-transcription factor II, a new partner of the glucose response element of the L-type pyruvate kinase gene, acts as an inhibitor of the glucose response. J Biol Chem 274:28385-28394
47. 47. Shih HM, Towle HC 1992 Definition of the carbohydrate response element of the rat S14 gene. Evidence for a common factor required for carbohydrate regulation of hepatic genes. J Biol Chem 267:13222-13228
48. 48. Shih H, Towle HC 1994 Definition of the carbohydrate response element of the rat S14 gene. Context of the CACGTG motif determines the specificity of carbohydrate regulation. J Biol Chem 269:9380-9387
49. 49. Lefrancois MA, Martinez A, Antoine B, Raymondjean M, Kahn A 1995 Upstream stimulatory factor proteins are major components of the glucose response complex of the L-type pyruvate kinase gene promoter. J Biol Chem 270:2640-2643
50. 50. Vallet VS, Henrion AA, Bucchini D, Casado M, Raymondjean M, Kahn A, Vaulont S 1997 Glucose-dependent liver gene expression in upstream stimulatory factor 2 [minus[/-mice. J Biol Chem 272:21944-21949
51. 51. Hasegawa J, Osatomi K, Wu RF, Uyeda K 1999 A novel factor binding to the glucose response elements of liver pyruvate kinase and fatty acid synthase genes. J Biol Chem 274:1100-1107
52. 52. Gregor PD, Sawadogo M, Roeder RG 1990 The adenovirus major late transcription factor USF is a member of the helix-loop-helix group of regulatory proteins and binds to DNA as a dimer. Genes Dev 4:1730-1740
53. 53. Wang GL, Jiang BH, Rue EA, Semenza GL 1995 Hypoxia-inducible factor 1 is a basic-helix-loop-helix-PAS heterodimer regulated by cellular O2 tension. Proc Natl Acad Sci USA 92:5510-5514
54. 54. Ebert BL, Gleadle JM, O'Rourke JF, Bartlett SM, Poulton J, Ratcliffe PJ 1996 Isoenzyme-specific regulation of genes involved in energy metabolism by hypoxia: similarities with the regulation of erythropoietin. Biochem J 313:809-814
55. 55. Firth JD, Ebert BL, Pugh CW, Ratcliffe PJ 1994 Oxygen-regulated control elements in the phosphoglycerate kinase 1 and lactate dehydrogenase A genes: similarities with the erythropoietin 3′ enhancer. Proc Natl Acad Sci USA 91:6496-6500
56. 56. Semenza GL, Jiang BH, Leung SW, Passantino R, Concordet JP, Maire P, Giallongo A 1996 Hypoxia response elements in the aldolase A, enolase 1, and lactate dehydrogenase A gene promoters contain essential binding sites for hypoxia-inducible factor 1. J Biol Chem 271:32529-32537
57. 57. Sogawa K, Nakano R, Kobayashi A, Kikuchi Y, Ohe N, Matsushita N, Fujii KY 1995 Possible function of Ah receptor nuclear translocator (Arnt) homodimer in transcriptional regulation. Proc Natl Acad Sci USA 92:1936-1940
58. 58. Swanson HI, Chan WK, Bradfield CA 1995 DNA binding specificities and pairing rules of the Ah receptor, ARNT, and SIM proteins. J Biol Chem 270:26292-26302
59. 59. Kvietikova I, Wenger RH, Marti HH, Gassmann M 1995 The transcription factors ATF-1 and CREB-1 bind constitutively to the hypoxia-inducible factor-1 (HIF-1) DNA recognition site. Nucleic Acids Res 23:4542-4550