Cyclosporin A eyedrops: Manufacturing, kinetics and indications in 2000;Collyre à la cyclosporine A: Fabrication, toxicité, pharmacocinétique et indications en l'an 2000

Journal Francais d'Ophtalmologie

Volumn 24, Issue 5, 2001, Pages 527-535

  Robert, P Y ^a   Leconte, V ^a   Olive C ^a   Ratsimbazafy, V ^b   Javerliat, M ^b   Adenis, J P ^b  

^a Service d'Ophtalmologie   (France)

^b DUPUYTREN UNIVERSITY HOSPITAL   (France)

Author keywords

Cornea; Cyclosporin; Dry eye; Eyedrops; Keratoplasty; Ocular surface

Indexed keywords

ALPHA CYCLODEXTRIN; COLLAGEN; CYCLOSPORIN A; EXCIPIENT; EYE DROPS; LIPOSOME; NANOCAPSULE; POLYESTER; SOLVENT; STEROID;

DRUG BIOAVAILABILITY; DRUG INDICATION; DRUG MANUFACTURE; DRUG STABILITY; DRUG STERILITY; DRY EYE; ENDOTHELIUM CELL; EPITHELIUM CELL; EYE DISEASE; EYE TOXICITY; FILTERING OPERATION; HERPES SIMPLEX KERATITIS; HUMAN; IMMUNOMODULATION; IMMUNOREGULATION; KERATITIS; KERATOCONJUNCTIVITIS SICCA; LIPOPHILICITY; PH; PUNCTATE KERATITIS; REVIEW; VERNAL CONJUNCTIVITIS;

BIOLOGICAL AVAILABILITY; CHEMISTRY, PHARMACEUTICAL; CORNEAL TRANSPLANTATION; CORNEAL ULCER; CYCLOSPORINE; DRUG CARRIERS; HUMANS; IMMUNOSUPPRESSIVE AGENTS; KERATITIS; LIPOSOMES; OPHTHALMIC SOLUTIONS; PATIENT SELECTION; TISSUE DISTRIBUTION;

EID: 0035005262     PISSN: 01815512     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Review

References (83)

1. Biological effects of cyclosporin A: A new antilymphocytic agent
2. Rabbit corneal allograft survival following topical administration of cyclosporin A
3. Prophylactic topical cyclosporine in experimental herpetic stromal keratitis
4. Lokale behandlung des homhauttransplantates beim menschen mit cyclosporin A
5. Local treatment of necrotizing scleritis with cyclosporin A
6. Treatment of severe vernal keratoconjunctivitis with cyclosporine A eyedrops
7. Usage de la cyclosporine A collyre dans la prévention du rejet de greffe de cornée chez l'homme. I. Évolution préopératoire de 4 yeux atteints de kératite métaherpétique
8. Cyclosporine A collyre dans la prévention du rejet de greffe de cornée à haut risque II. Résultats cliniques post-opératoires
9. Stability of cyclosporine 1% in artificial tears
10. The effect of topical cyclosporin A on rabbit cornea: A clinical and electron microscope study
11. Topical use of cyclosporine in the treatment of vernal keratoconjunctivitis
12. Pilot trial of cyclosporine 1% ophthalmic ointment in the treatment of keratoconjunctivitis sicca
13. Therapeutic options in ocular allergic disease
14. Untersuchungen zur toxizität von cyclosporin A für hornhautendothel in de gewebekultur
15. Pharmacokinetics of topical cyclosporin A in the rabbit eye
16. Repetitive instillations of cyclosporin A eyedrop induce pupillary constriction and anterior chamber inflammation-like reactions in rabbits
17. Cyclosporin-A and its metabolites in the anterior chamber after topical and systemic application as determined with high-performance liquid chromatography-electrospray mass spectrometry
18. Penetration of topical cyclosporine into the rabbit cornea, aqueous humor and serum
19. Distribution of cyclosporin A in ocular tissues after topical administration to albino rabbits and beagle dogs
20. Topical cyclosporine A in the management of postkeratoplasty glaucoma and corticosteroid-induced ocular hypertension (CIOH) and the penetration of topical 0.5% cyclospotine A into the cornea and anterior chamber
21. Corneal concentration and systemic absorption of cyclosporin-A following its topical application in the rabbit eye
22. Influence of topically applied cyclosporine A in olive oil on corneal epithelium permeability
23. Influence of topical cyclosporine A and dissolvent on corneal epithelium permeability of fluorescein
24. Penetration of cyclosporin A into the rabbit cornea and aqueous humor after topical drop and collagen shield administration
25. The effect on the cornea of alpha cyclodextrin vehicle for cyclosporin eye drops
26. The collagen shield. A new vehicle for delivery of cyclosporin A to the eye
27. Collagen as a delivery system for hydropholic drugs studies with cyclosporine
28. Cyclosporine in collagen particles: Corneal penetration and suppression of allograft rejection
29. Ocular absorption of cyclosporine A from liposomes incorporated into collagen shields
30. Polyester nanocapsules as new topical ocular delivery systems for cyclosporin A
31. Effect of cyclosporine A formulations on bovine corneal absorption: Ex-vivo study
32. Absorption intra-oculaire du collyre cyclosporine A
33. Penetration of topical cyclosporine into the rabbit cornea, aqueous humor and serum
34. Local cyclosporine therapy for experimental autoimmune uveitis in rats
35. Prolonged survival of allogeneic grafts in rabbits treated with topically applied cyclosporin A: Systemic absorption and local immunosuppressive effect
36. Corneal concentration and systemic absorption of cyclosporin A following its topical application in the rabbit eye
37. Topical cyclosporine in high-risk corneal transplants
38. Use of topical cyclosporin A in a primary Sjogren's syndrome mouse model
39. Effect of topical cyclosporin A on conjunctival T cells in patients with secondary Sjogren's syndrome
40. Effect of cyclosporin A eyedrops on tear secretion in rabbit
41. Characteristics of a canine model of KCS: Effective treatment with topical cyclosporine
42. Topical administration of cyclosporine for treatment of keratoconjunctivitis sicca in dogs
43. Clinical evolution of 1% cyclosporine for topical treatment of keratoconjunctivitis sicca in dogs
44. Cellular immunity in dogs with keratoconjunctivitis sicca before and after treatment with topical 2% cyclosporine
45. Effect of topical cyclosporin A on conjunctival T cells in patients with secondary Sjögren's syndrome
46. Topical cyclosporin treatment of keratoconjunctivitis sicca in secondary Sjögren's syndrome
47. Cyclosporine improves dry eye symptoms, studies say
48. Topical cyclosporine inhibits mast cell- mediated conjunctivitis
49. Topical cyclosporin in vernal keratoconjunctivitis
50. An immunohistochemical study of topical cyclosporine in vernal keratocunjunctivitis
51. Topical cyclosporine and glaucoma drainage implant surgery in rabbits
52. Topical cyclosporine as a possible new antimetabolite in trabeculectomy
53. Topical cyclosporin A in the treatment of anterior segment inflammatory disease
54. Ultrastructural and immunohistochemical study on the effect of topical cyclosporin A in the rabbit eye
55. Experimental study on cyclosporin A (CsA) acting on rejection of heterolamellar corneal transplantation
56. Mixed lymphocyte culture responses in rabbits undergoing corneal grafting and topical cyclosporine treatment
57. Prolongation of corneal allograft survival with liposome-encapsulated cyclosporine in the rat eye
58. Experimental corneal allo-rejection in rabbits using cyclosporin-collagen schields
59. Topical steroid, cyclosporin A, and the outcome of rat corneal allografts
60. Colono de cyclosporine al 2% y 4% en el rechazo agudo del transplante corneal
61. The inhibition of keratoplasty rejection with topical cyclosporin A
62. Therapeutic use of topical cyclosporine
63. Local therapy of corneal allograft rejection with cyclosporine
64. Local use of cyclosporin in non bacterial corneal ulceration
65. Survival of rabbit limbal stem cell allografts after administration of cyclosporin A
66. Topical cyclosporin as an adjunct to topical acyclovir treatment in herpetic stromal keratitis
67. Treatment of HSV-1 stromal keratitis with topical cyclosporin A: A pilot study
68. Immunological analysis and treatment of Mooren's ulcer with cyclosporin A applied topically
69. Topical treatment of severe corneal ulcers with cyclosporine A
70. Topical cyclosporine therapy for ulcerative keratitis associated with rheumatoid arthritis
71. Paracentral rheumatoid corneal ulceration
72. Topical cyclosporin A in Thygeson's superficial punctate keratitis
73. Effect of topical cyclosporin A on Thygeson's superficial punctate keratitis
74. Immunologic and clinical evaluation of postsurgical necrotizing sclerocorneal ulceration
75. Effects of synthetic inhibitor of metalloproteinase and cyclosporin A on corneal haze after excimer laser photorefractive keratectomy in rabbits
76. Local cyclosporin A therapy of nummuli after epidemic keratoconjunctivitis. Case report
77. Corneal neovascularization induced by xenografts or chemical cautery. Inhibition by cyclosporin A
78. Topical application of cyclosporin ophthalmic solution containing alpha-cyclodextrin in experimental uveitis
79. Local cyclosporine therapy for experimental autoimmune uveitis in rats