Downregulation of the ERK 1 and 2 mitogen activated protein kinases using antisense oligonucleotides inhibits proliferation of porcine vascular smooth muscle cells

Atherosclerosis

Volumn 156, Issue 2, 2001, Pages 289-295

  Fisher, M ^a   Liu, B ^a   Glennon, P E ^b   Southgate, K M ^c   Sale, E M ^d   Sale, G J ^d   Lewis, M J ^a   Groves, P H ^a  

^a CARDIFF UNIVERSITY   (United Kingdom)

^b ADDENBROOKE S HOSPITAL   (United Kingdom)

^c UNIVERSITY OF BRISTOL   (United Kingdom)

^d UNIVERSITY OF SOUTHAMPTON   (United Kingdom)

Author keywords

Antisense oligonucleotides; Cell proliferation; Protein kinases; Second messengers; Signal transduction; Smooth muscle; Vasculature

Indexed keywords

ANTISENSE OLIGODEOXYNUCLEOTIDE; MITOGEN ACTIVATED PROTEIN KINASE;

ANIMAL CELL; ARTERY INJURY; ARTICLE; CELL PROLIFERATION; CELL VIABILITY; CONTROLLED STUDY; GENETIC TRANSFECTION; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN CONTENT; SMOOTH MUSCLE FIBER; SWINE; VASCULAR SMOOTH MUSCLE;

ANALYSIS OF VARIANCE; ANIMALS; BLOTTING, WESTERN; CELL DIVISION; CELLS, CULTURED; DOWN-REGULATION; MICROSCOPY, FLUORESCENCE; MITOGEN-ACTIVATED PROTEIN KINASE 1; MITOGEN-ACTIVATED PROTEIN KINASE 3; MITOGEN-ACTIVATED PROTEIN KINASES; MUSCLE, SMOOTH, VASCULAR; OLIGONUCLEOTIDES, ANTISENSE; PROBABILITY; SENSITIVITY AND SPECIFICITY; SWINE;

EID: 0035003548     PISSN: 00219150     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0021-9150(00)00656-0     Document Type: Article

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